OpenAI Shifts ChatGPT to Autonomous Computer-Use Agents via Astra

Greg Brockman on Astra and the Future of OpenAI — TBPN

TBPN

OpenAI is moving beyond prompt-and-response chatbots toward unified, multimodal agents that operate standard software interfaces visually like humans to automate complex workflows without brittle API connectors.

AI-assisted summary of Greg Brockman on Astra and the Future of OpenAI — original source. Check the original for full context.

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## Background Published on YouTube by TBPN on September 8, 2026, this interview features OpenAI Co-Founder and President Greg Brockman. The page description highlights discussions on OpenAI's solution to the Navier-Stokes Millennium Prize problem, Astra and the future of computer use, the shift from chatbots to autonomous agents, ChatGPT's role in healthcare, and operational lessons from Operator.

## TL;DR Greg Brockman discusses OpenAI's milestone proof and counterexample for the Navier-Stokes Millennium Prize problem, framing it as a breakthrough signaling AI's capacity to produce genuinely novel scientific knowledge. He details how Astra represents a new threshold in agentic computer use by letting models operate complex software like Blender visually and functionally like humans to solve practical real-world problems. Brockman also outlines OpenAI's three-pillar strategy in healthcare—connecting consumer queries, clinician tooling, and enterprise EHR systems like Epic—while emphasizing how long-term memory can overcome fragmented medical silos. Finally, he reflects on the iterative lessons learned from Operator and OpenAI's cultural pivot back to high-conviction startup execution to deliver unified multimodal workflows.

## Atmosphere & style The conversation carries an energetic, pragmatic, and technically ambitious tone, seamlessly shifting between high-level theoretical milestones and granular, practical user workflows. The dynamic between the TBPN hosts and Brockman is fluid and focused, striking a balance between industry analysis and deeply personal reflections, notably when Brockman recounts his wife's multi-year struggle across siloed medical specialists. Listening feels like an intimate, behind-the-scenes product debrief with a builder who is visibly energized by grassroots user creations and the relentless drive to push experimental AI past utility thresholds.

## Key takeaways - [00:00](https://www.youtube.com/watch?v=qNxuxwb9ksA&t=0s) OpenAI's model solved the Navier-Stokes existence and smoothness Millennium Prize problem with a counterexample and singularity proof, marking a transition from retrieving known data to generating novel scientific knowledge. - [00:00](https://www.youtube.com/watch?v=qNxuxwb9ksA&t=0s) Autonomous mathematical reasoning serves as a foundational stepping stone toward practical superintelligence, accelerating downstream discoveries in fluid dynamics, aerodynamics, and drug design. - [03:19](https://www.youtube.com/watch?v=qNxuxwb9ksA&t=199s) Astra represents a major capability threshold in computer use, allowing AI to directly control complex software like Blender for 3D modeling, architecture, and physical manufacturing. - [05:50](https://www.youtube.com/watch?v=qNxuxwb9ksA&t=350s) AI interaction is rapidly shifting from reactive, turn-based chatbots to proactive autonomous agents running extended workflows in the background. - [05:50](https://www.youtube.com/watch?v=qNxuxwb9ksA&t=350s) OpenAI aims to unify fragmented developer and power-user tools, abstracting away model selection and technical parameters so users can focus on setting high-level objectives. - [08:14](https://www.youtube.com/watch?v=qNxuxwb9ksA&t=494s) OpenAI faces a 'discovery problem' where early adopters still view ChatGPT through a basic chatbot mental model despite massive agentic upgrades across its 1+ billion weekly active users. - [11:14](https://www.youtube.com/watch?v=qNxuxwb9ksA&t=674s) Product demonstrations are shifting toward concrete, tangible workflows—such as turning rough sketches into physically manufactured goods—to spark real-world user adoption. - [14:50](https://www.youtube.com/watch?v=qNxuxwb9ksA&t=890s) Crossing key quality and controllability thresholds in image generation unlocks integrated multimodal creation workflows, including automated slide decks and complete website generation. - [16:36](https://www.youtube.com/watch?v=qNxuxwb9ksA&t=996s) OpenAI's healthcare ecosystem is built on three pillars: consumer health (over 300 million weekly users), clinician-focused literature tools, and enterprise electronic health record (EHR) integrations with systems like Epic. - [16:36](https://www.youtube.com/watch?v=qNxuxwb9ksA&t=996s) Persistent long-term memory across chat threads allows AI to detect subtle cross-symptom patterns over time, overcoming the diagnostic blind spots inherent in siloed medical specialties. - [20:51](https://www.youtube.com/watch?v=qNxuxwb9ksA&t=1251s) Astra replaces brittle, hardcoded API connectors with generalized human-like visual interaction across any software interface, building directly on empirical learnings from Operator. - [20:51](https://www.youtube.com/watch?v=qNxuxwb9ksA&t=1251s) OpenAI restructured its organizational execution away from diffuse, hyperscaler-style experimentation and back into a focused 'startup mode' to accelerate product delivery.

## Detailed walkthrough ### [00:00](https://www.youtube.com/watch?v=qNxuxwb9ksA&t=0s) Solving the Navier-Stokes Millennium Prize Problem

OpenAI Co-Founder and President Greg Brockman opens the conversation by discussing the announcement that OpenAI's model solved the Navier-Stokes existence and smoothness problem, one of the seven Millennium Prize Problems in mathematics. The model produced an elegant proof and counterexample demonstrating that these theoretical equations can form singularities or break down under certain conditions. While Navier-Stokes equations have foundational real-world applications in fluid dynamics—ranging from modeling ocean currents and atmospheric weather to understanding aircraft aerodynamics and turbulence—Brockman emphasizes that the most profound takeaway is what the milestone signals about the state of AI: models have reached the capability to generate genuinely new human knowledge and solve problems previously considered out of reach.

When asked whether such esoteric mathematical breakthroughs will touch everyday life, cure cancer, or merely serve as a recruiting beacon for elite researchers, Brockman explains that the underlying methods represent a stepping stone toward practical superintelligence. The capacity of models to autonomously reason through deep, long-standing scientific barriers directly accelerates the timeline for high-impact applications, making ambitions like designing new therapeutics, curing complex diseases, and accelerating scientific discovery tangible realities.

- **Milestone:** Finding a counterexample/singularity proof for the long-standing Navier-Stokes Millennium Prize problem. - **Direct Domain Impact:** Enhanced modeling of fluid dynamics, air turbulence, and ocean currents. - **Broader Trajectory:** Transitioning AI from retrieving known information to generating novel scientific discoveries.

---

[03:19](https://www.youtube.com/watch?v=qNxuxwb9ksA&t=199s) Astra Launch and Reaching a New Threshold in Computer Use

Turning to consumer and developer excitement, the hosts bring up the viral weekend launch of Astra, where users flooded social media with complex 3D projects built in Blender. Brockman expresses his excitement and humility at the community's reaction, noting that Astra represents a distinct new threshold in computer use where AI directly interacts with complex software applications. Users have moved beyond simple text generation to map physical locations into 3D models, iterate on architectural remodels, and engineer custom physical components—including a user who modeled a specialized physical hair catcher for a shower drain to manufacture at home.

```mermaid flowchart TD accTitle: Evolution of AI Interaction Paradigms accDescription: Flowchart illustrating the transition from traditional chat prompting to direct agentic computer use and physical manufacturing.

subgraph Traditional["1. Conversational Chat"] A["User Text Prompt"] --> B["Low-Level LLM Text Output"] end

subgraph Agentic["2. Agentic Computer Use (Astra)"] C["High-Level Goal & Intent"] --> D["Agent Operates Software Tools\n(e.g., Blender, Code Execution)"] D --> E["Complex 3D Digital Assets & CAD Models"] end

subgraph Physical["3. Real-World Execution"] E --> F["Rapid Physical Prototyping & Manufacturing"] end

Traditional -.-> Agentic Agentic --> Physical ```

Brockman highlights that while grand mathematical challenges grab headlines, empowering individuals to solve mundane, practical problems in their daily lives represents the true promise of AI. Rather than requiring users to master complex, specialized software interfaces, models like Astra act as personal multipliers, turning everyday people into capable creators and designers.

---

[05:50](https://www.youtube.com/watch?v=qNxuxwb9ksA&t=350s) The Evolution from Chatbots to Proactive Autonomous Agents

Addressing the fragmentation of modern AI setups—where power users juggle local GPUs, Codex threads, cloud sandboxes, and desktop clients—Brockman outlines OpenAI's roadmap toward unification. The ultimate goal is to abstract away low-level technical parameters, context window management, and model selection. Humans should remain accountable for setting high-level objectives and oversight while the AI operates as an amplifier—a "rocket ship for the mind"—that takes care of underlying software execution seamlessly.

OpenAI is observing a dual-engine dynamic in usage. While traditional chat remains massive and growing, deep productivity and agentic workflows have experienced a near-vertical wall of adoption following the release of ChatGPT Work. Brockman explains that these separate interaction modes will converge into persistent, proactive assistants capable of autonomously delegating and executing complex tasks over extended periods.

- **ChatGPT Weekly Active Users:** Well over 1 billion weekly active users across global education, health, and consumer use cases. - **Workflow Shift:** Rapid transition from short prompt-and-response turns to proactive, background agentic execution. - **Interface Goal:** Unifying separate interfaces so underlying tool use (such as Blender or code execution) fades into the background.

---

[08:14](https://www.youtube.com/watch?v=qNxuxwb9ksA&t=494s) The Discovery Problem and First-Mover Dynamics in AI

The conversation shifts to the unique strategic friction facing market leaders: the "first-mover disadvantage" where billions of early adopters formed their mental model of ChatGPT based on early conversational iterations and remain unaware of rapid advances in agentic capabilities. While some advanced users already maintain persistent background agents—such as automated bots tracking SpaceX launches and countdown delays—the vast majority of casual users still see a simple text prompt box and do not know what tasks they can delegate.

Brockman frames this as the fundamental "discovery problem" of AI. Because an LLM interface is fundamentally open-ended, users struggle to discern the difference between a standard query box and an advanced agentic environment. OpenAI is addressing this by building self-knowledge into the model itself, enabling ChatGPT to analyze a user's intent and proactively suggest integrations, authentication steps, or alternative prompting strategies to execute multi-step workflows.

- **Scale of User Base:** Over 1 billion weekly active users, with another 1 to 1.5 billion people who have tried the tool in the past and can be re-engaged. - **ChatGPT for Health:** 300 million people use ChatGPT every week for health-related queries. - **Onboarding Evolution:** Transitioning from passive text boxes to self-guiding, proactive assistants that teach users how to leverage new capabilities.

---

[11:14](https://www.youtube.com/watch?v=qNxuxwb9ksA&t=674s) Concrete Product Marketing and Real-World Design Workflows

The hosts and Brockman discuss how AI companies must evolve their product communication, drawing a comparison to Apple's classic marketing strategy. Rather than relying solely on abstract brand campaigns or esoteric demonstrations that general audiences cannot relate to, marketing needs to spotlight tangible, granular features—like showcasing the exact mechanics of designing a real-world object.

Brockman reflects on the launch of ChatGPT Images 2.5 as a prime example of this philosophy in action. In the launch demonstration, a simple sketch of a candle holder was visualized, varied, and subsequently turned into a physical manufactured product. When users see a concrete bridge from an initial conceptual prompt to a tangible, finished physical item, the utility immediately resonates, sparking their own exploration into practical use cases.

---

[13:30](https://www.youtube.com/watch?v=qNxuxwb9ksA&t=810s) Asking the AI What It Can Do and the Future of Image Generation

The section concludes with a discussion on user behavior and prompt discovery. The hosts note a common pattern among professionals—such as real estate developers evaluating complex deal memos or users deciding whether to execute a Blender script locally via Codex or in the cloud—who still overlook the simplest strategy: directly asking the AI how it can help structure and solve their task.

Turning to the evolution of generative visual media, the host shares an experience of spending hours on a weekend iterating through hundreds of prompts to design custom furniture, raising the question of where image models go once basic generation feels "solved." Brockman prepares to delve into how image generation is transitioning from standalone static rendering to deeply integrated, functional design tools.

[14:50](https://www.youtube.com/watch?v=qNxuxwb9ksA&t=890s) Image Generation Thresholds and Multimodal Creation

The discussion turns to the downstream impact of advanced image models. The host observes that when users can snap a photo of a physical space and visualize countless variations, it prompts real-world action because people can finally see an idea clearly and decide to make it a reality. Greg Brockman agrees, emphasizing that crossing key capability thresholds unlocks fundamentally new applications that are hard to predict in advance. Within knowledge work, professional workflows, and marketing, being below a certain quality threshold turns generative AI into merely a "cool concept" that produces unusable final material. Once a model achieves precise edit control, rapid iteration, creative diversity, and responsive human interplay, entirely new use cases emerge.

```mermaid flowchart TD accTitle: Multimodal Capability Convergence subgraph Core["Unified Multimodal Package"] IMG["Image Generation & Editing"] VCE["Voice Interaction"] COD["Code Execution & Logic"] end

subgraph Outcomes["Downstream Creation"] SLD["Automated Slide Creation"] WEB["End-to-End Website Building"] WRK["Knowledge & Professional Artifacts"] end

Core --> Outcomes ```

Brockman highlights that native image generation embedded directly into the workflow provides a distinct competitive advantage for OpenAI when creating artifacts like polished presentation slides and dynamic websites. Rather than viewing text, voice, coding, and image generation as isolated silos, OpenAI treats them as a single, unified package designed to empower users to "create anything that you imagine."

- **Quality Threshold Rule:** Models below the threshold remain conceptual demos; crossing the bar transforms them into enterprise-ready tools for marketing and knowledge work. - **Workflow Synergy:** Integrated image generation directly powers downstream creation tools like slide decks and website generation.

---

[16:36](https://www.youtube.com/watch?v=qNxuxwb9ksA&t=996s) ChatGPT Health: The Three Pillars and Long-Term Memory

Turning to healthcare, the host notes that while users already synthesize lab results or sleep scores with ChatGPT, OpenAI’s ambitions go much deeper. Brockman outlines OpenAI's healthcare strategy across three distinct pillars: consumer health, clinician tooling, and enterprise healthcare infrastructure. Over 300 million people already bring health-related queries to ChatGPT each week. For clinicians, OpenAI is developing specialized models tuned with direct citations to authoritative medical literature. On the enterprise side, OpenAI sells directly to healthcare systems and hospitals, including native integrations with EHR systems like Epic. While each pillar is built to deliver independent value, combining them on a unified platform eliminates the friction of patients having to manually transport medical records between siloed specialists. Furthermore, such platform integration could solve clinical trial enrollment bottlenecks by identifying eligible patients who would benefit from specific drug therapies.

```mermaid flowchart LR accTitle: OpenAI Three-Pillar Healthcare Strategy subgraph Pillars["OpenAI Healthcare Ecosystem"] direction TB C["1. Consumer Platform<br/>(300M weekly health queries)"] CL["2. Clinician Tools<br/>(Literature citations, bottom-up)"] E["3. Enterprise & Hospitals<br/>(Direct sales, Epic EHR integration)"] end

subgraph Synergies["Downstream Systemic Benefits"] REC["Unified Medical Record Portability"] TRI["Automated Clinical Trial Matching"] PAT["Cross-Symptom Pattern Recognition"] end

Pillars --> Synergies ```

The conversation explores how long-term memory will fundamentally reshape AI diagnostics. Because ChatGPT can recall context from weeks prior across disparate threads, it can detect subtle cross-symptom patterns that human clinicians might miss over years. Brockman shares a poignant personal example regarding his wife's healthcare journey: she spent five years visiting various specialists who each examined only "one part of the elephant" in functional isolation. It was ultimately her allergist who recognized that her diverse symptoms stemmed from a single underlying genetic condition affecting multiple subsystems. Brockman reflects on how many people suffer without answers simply because medicine is fragmented, underscoring AI's potential to combine broad holistic memory with deep domain expertise.

- **Scale:** Over 300 million weekly active users engage with health-related queries. - **EHR Integration:** Direct workflow integration with enterprise electronic health record platforms, specifically Epic. - **Clinical Impact:** Real-world anecdotes where ChatGPT's cross-checking enabled patients to identify critical diagnoses and save lives.

---

[20:51](https://www.youtube.com/watch?v=qNxuxwb9ksA&t=1251s) From Operator to Astra: Computer Use and Startup Velocity

When asked whether OpenAI's earlier project, Operator, was a failed detour or a stepping stone toward modern computer use, Brockman contextualizes it as a classic example of iterative deployment. Operator was a cloud-based system that attempted autonomous computer operation, but it remained "below threshold"—slow, inaccurate, and frustrating to use. Rather than abandoning the initiative, the team committed to the long-term grind, systematically burning down technical blockers over the course of the year to achieve a breakthrough milestone with Astra.

Brockman explains that past agentic workflows relied heavily on brittle, painstakingly coded API connectors. Astra, by contrast, interacts with computers visually and functionally the exact same way humans do, unlocking universal interaction across any software designed for people. The host notes that OpenAI's operational style underwent a visible shift: while the prior year felt like a sprawling hyperscaler running experiments with low hit-rate expectations, the company restructured itself back into high-conviction "startup mode." Brockman affirms that rallying the entire company around unified focus and execution has been instrumental in delivering cohesive, multimodal agentic products aligned with OpenAI's core mission.

- **Interface Shift:** Replaced fragile, custom API connectors with generalized human-like computer vision and interaction. - **Evolution:** Operator provided the empirical deployment data needed to refine the underlying models that power Astra. - **Cultural Pivot:** Transitioned organizational execution from diffuse big-tech experimentation back to high-intensity startup alignment and singular focus.

## Notable quotes > [00:00](https://www.youtube.com/watch?v=qNxuxwb9ksA&t=0s) models have reached the capability to generate genuinely new human knowledge and solve problems previously considered out of reach. — Greg Brockman

> [03:19](https://www.youtube.com/watch?v=qNxuxwb9ksA&t=199s) Astra represents a distinct new threshold in computer use where AI directly interacts with complex software applications. — Greg Brockman

> [05:50](https://www.youtube.com/watch?v=qNxuxwb9ksA&t=350s) rocket ship for the mind — Greg Brockman

> [08:14](https://www.youtube.com/watch?v=qNxuxwb9ksA&t=494s) discovery problem — Greg Brockman

> [14:50](https://www.youtube.com/watch?v=qNxuxwb9ksA&t=890s) crossing key capability thresholds unlocks fundamentally new applications that are hard to predict in advance. — Greg Brockman

> [14:50](https://www.youtube.com/watch?v=qNxuxwb9ksA&t=890s) create anything that you imagine — Greg Brockman

> [16:36](https://www.youtube.com/watch?v=qNxuxwb9ksA&t=996s) one part of the elephant — Greg Brockman

> [20:51](https://www.youtube.com/watch?v=qNxuxwb9ksA&t=1251s) below threshold — Greg Brockman

> [20:51](https://www.youtube.com/watch?v=qNxuxwb9ksA&t=1251s) Astra, by contrast, interacts with computers visually and functionally the exact same way humans do, unlocking universal interaction across any software designed for people. — Greg Brockman

## Mentioned Greg Brockman, OpenAI, TBPN, Astra, ChatGPT, ChatGPT Work, ChatGPT Images 2.5, Operator, Codex, Blender, Navier-Stokes, Millennium Prize Problems, Epic, Apple, SpaceX, Ramp, Public, Cisco, Console, CrowdStrike, Figma, MongoDB, NYSE, Railway, Shopify

## Video description This is our full interview with OpenAI Co-Founder and President Greg Brockman.

We discuss how OpenAI solved the Navier-Stokes Millennium Prize problem, what Astra reveals about the future of computer use, why AI is shifting from chatbots to agents that can actually do work for you, how ChatGPT could transform healthcare, why image generation is unlocking entirely new applications, what OpenAI learned from Operator, and where AI goes from here.

TBPN is made possible by: Ramp - https://ramp.com Public - https://public.com Cisco - https://www.cisco.com Console - https://www.console.com CrowdStrike - https://www.crowdstrike.com Figma - https://www.figma.com MongoDB - https://www.mongodb.com NYSE - https://www.nyse.com Railway - https://railway.com Shopify - https://www.shopify.com/ Codex - http://openAI.com/codex

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[Source](https://www.youtube.com/watch?v=qNxuxwb9ksA)

中文简报

OpenAI通过Astra将ChatGPT转向自主计算机使用智能体 OpenAI正超越提示-响应式聊天机器人,迈向统一的多模态智能体;这类智能体能像人类一样通过视觉操作标准软件界面,无需脆弱的API连接器即可自动化复杂工作流。 Greg Brockman讨论了OpenAI针对Navier-Stokes千禧年大奖难题提出的里程碑式证明与反例,并将其视为标志着AI有能力产生真正全新科学知识的突破。他详细阐述了Astra如何代表智能体计算机使用的新门槛——通过让模型在视觉和功能上像人类一样操作Blender等复杂软件来解决现实世界的实际问题。Brockman还概述了OpenAI在医疗领域的“三大支柱”战略,即连接消费者咨询、临床医生工具以及Epic等企业级EHR系统,同时强调了长期记忆如何打破碎片化的医疗数据孤岛。最后,他反思了从Operator中汲取的迭代经验,以及OpenAI在文化上重新转向坚定信念的初创公司式执行力,以交付统一的多模态工作流。 OpenAI的模型通过反例和奇点证明解决了Navier-Stokes存在性与光滑性千禧年大奖难题,标志着从检索已知数据向生成全新科学知识的转变。 (0:00) 自主数学推理是通向实用超级智能的基础跳板,能够加速流体动力学、空气动力学和药物设计等下游领域的探索发现。 (0:00) Astra代表了计算机使用方面的重大能力跨越,允许AI直接控制Blender等复杂软件进行3D建模、建筑设计和实体制造。 (3:19) AI交互正迅速从被动的轮流对话式聊天机器人,转向在后台运行扩展工作流的主动自主智能体。 (5:50) OpenAI旨在整合碎片化的开发者与高级用户工具,屏蔽模型选择和技术参数的复杂性,让用户能够专注于设定高层目标。 (5:50)

Reading summary

OpenAI President Greg Brockman argues that artificial intelligence is transitioning from passive text generation to proactive scientific reasoning and direct computer interaction, requiring unified multimodal platforms that turn high-level user intent into practical real-world execution. Autonomous Reasoning and Scientific Knowledge Generation (0:00) Brockman highlights OpenAI's model identifying a singularity counterexample for the Navier-Stokes existence and smoothness problem—one of mathematics' Millennium Prize Problems—as evidence that AI can now generate genuinely novel human knowledge rather than merely retrieving known information. While Navier-Stokes equations directly govern fluid dynamics modeling in weather, ocean currents, and aeronautics, Brockman views the mathematical milestone primarily as validation of the model's underlying reasoning depth. Brockman claims that the ability to autonomously reason through long-standing scientific barriers serves as a critical stepping stone toward practical superintelligence. In his view, these reasoning breakthroughs will compress scientific research timelines, making real-world ambitions like targeted therapeutics and the curing of complex diseases technologically viable. Transitioning from Chatbots to Agentic Computer Use (3:19) The launch of Astra represents what Brockman describes as a new threshold in computer use: AI interacting directly with complex software interfaces through vision, just as human users do, rather than through fragile API connectors. Brockman contrasts Astra with its predecessor, Operator—a cloud-based tool that OpenAI acknowledged remained below the usability threshold due to latency and errors. Following an organizational pivot back to focused startup execution, the team refined these agentic capabilities, enabling users to direct models to design complex 3D assets in Blender and produce physical objects like customized shower drain hair catchers. OpenAI observes this shift as part of a dual-engine dynamic: while conversational chat remains broad, deep productivity workflows are accelerating via ChatGPT Work. Brockman outlines a roadmap to abstract away technical parameters, local and cloud sandboxes, and context window management, aiming to unify separate workflows into proactive background agents for the platform's more than 1 billion weekly active users. Overcoming Interface Discovery Through Concrete Workflows (8:14) Despite reaching over 1 billion weekly active users and an additional 1 to 1.5 billion past users eligible for re-engagement, OpenAI faces a distinct discovery challenge. Brockman explains that early adopters still view ChatGPT through the mental model of a simple text prompt box, often unaware of multi-step agentic capabilities or the basic option to ask the AI how to structure a task. To counter this first-mover friction, OpenAI is designing models with self-knowledge to analyze intent and proactively guide users toward relevant integrations and workflows. Brockman emphasizes that AI product communication must mirror Apple's strategy of spotlighting concrete, granular features over abstract marketing. Pointing to ChatGPT Images 2.5—where a simple sketch of a candle holder was modified and manufactured into a physical product—he argues that crossing critical fidelity and control thresholds allows tightly integrated multimodal tools (combining image generation, voice, and code) to power practical downstream tasks like dynamic website generation and slide design. Reforming Healthcare Through Long-Term Memory Integration (16:36) Healthcare has become a major operational focus for OpenAI, with Brockman reporting that over 300 million users submit health-related questions weekly. The company's healthcare strategy rests on three interconnected pillars: consumer self-navigation, clinician-facing tools grounded in authoritative medical literature citations, and enterprise hospital infrastructure integrated directly into electronic health record platforms such as Epic. Brockman asserts that combining these layers can eliminate systemic frictions, including medical record transfer across disparate providers and patient recruitment bottlenecks in clinical trials. A central component of this strategy is cross-thread, long-term memory. Drawing on a personal account of his wife's five-year medical journey across isolated specialists before an allergist diagnosed an underlying genetic condition, Brockman argues that persistent AI memory can detect subtle cross-symptom patterns over weeks or years that human physicians, operating within specialized silos, frequently miss. While Brockman outlines a comprehensive vision where unified reasoning models autonomously operate software, conduct scientific discovery, and assist medical decisions, OpenAI faces the immediate practical hurdle of educating more than a billion users to move beyond basic conversational prompts into complex, agentic delegation.

精炼阅读摘要

OpenAI 联合创始人兼总裁 Greg Brockman 表示,人工智能正跨越关键能力阈值,从被动检索已有信息的文本框进化为能够推导未知科学前沿、自主操作复杂软件并协助系统性医疗的通用智能体。 前沿数学突破与生成新知识的能力跃迁 (0:00) Brockman 指出,OpenAI 的模型成功证明并给出了纳维-斯托克斯(Navier-Stokes)存在性与光滑性问题的反例,表明该方程在特定条件下会产生奇点或失效。作为数学界的七大千禧年难题之一,纳维-斯托克斯方程是模拟大气气象、洋流以及飞机空气动力学与湍流的基础。Brockman 强调,这一里程碑的核心意义不在于学术荣誉本身,而在于证实了 AI 模型已具备生成人类全新科学知识的能力,跨越了以往仅能总结既有经验的局限。 针对此类深奥数学突破是否脱离现实生活的质疑,Brockman 解释称,这些底层推理机制是迈向实用型超级智能的垫脚石。当模型拥有自主攻克长期科研壁垒的逻辑推理能力后,将直接缩短高价值实际应用的研发周期,使新型药物设计、攻克复杂疾病以及加速材料科学发现成为切实的可能。 从 Operator 到 Astra:计算机使用范式的代际跨越 (3:19) 在谈及近期发布并引发社区热潮的 Astra 时,Brockman 指出该系统标志着计算机使用进入了全新阶段。早期项目 Operator 作为云端自主操作系统的尝试,因速度慢、精度差且使用体验不佳而处于可用阈值之下。然而,团队将 Operator 作为获取真实部署数据的试验场,花费一年时间系统性攻克技术瓶颈,最终推动了 Astra 的诞生。不同于以往依赖定制且极其脆弱的底层 API 接口,Astra 能够像人类一样通过屏幕视觉与交互逻辑直接操控复杂软件。 在实际应用中,用户已使用 Astra 在 3D 建模软件 Blender 中构建复杂模型、进行建筑重构迭代,甚至完成定制物理部件的工程设计——例如有用户成功设计并制造了淋浴地漏毛发收集器。Brockman 认为,AI 的核心价值不仅在于解决宏大科学问题,更在于消除复杂专业界面的学习门槛,让普通人能够直接借助高层意图将创意转化为实体资产。同时,OpenAI 在组织层面也完成了从宽泛实验到聚焦高执行力“初创模式”的回归。 平台发现难题与向后台常驻智能体演进 (8:14) 目前 ChatGPT 已拥有超过 10 亿周活跃用户,同时还有 10 亿至 15 亿曾使用过的历史用户。然而,庞大的规模也带来了“先发劣势”:绝大多数早期用户对 ChatGPT 的认知仍停留在简单的单轮文本问答,无法意识到其在复杂任务执行方面的飞跃。部分高级用户已经能够部署后台常驻智能体(例如自动化追踪 SpaceX 火箭发射与倒计时延误),但普通用户由于面对完全开放式的空白输入框,往往不知道可以向 AI 委派哪些工作。 OpenAI 正在将自我引导能力内置到模型中,使系统能够主动理解用户意图并建议多步骤集成工作流。自 ChatGPT Work 推出以来,深度生产力与智能体工作流呈现出几乎垂直的爆发式增长。Brockman 表示,未来的终极目标是抹平底层模型选择、上下文窗口管理和算力沙盒等碎片化技术细节,使模型在后台自主执行复杂软件任务,而人类仅负责设定高层目标与监督。 多模态能力阈值与端到端创作集成 (14:50) Brockman 提出了“能力阈值法则”:在知识工作与专业设计领域,低于特定质量阈值的生成式 AI 只能充当博人眼球的概念演示,无法产出真正可用的成果;一旦跨越该阈值,精准编辑控制、快速迭代与多样化表达将催生出全新的工作模式。例如在 ChatGPT Images 2.5 的发布演示中,模型不仅能根据草图生成烛台方案,还能无缝衔接至实体制造流程,这种直接连接虚拟设计与物理产品的体验彻底激活了现实生产力。 OpenAI 并不将文本、语音、代码和图像视作孤立功能,而是将其打包为原生的统一多模态系统。将原生图像生成深度嵌入整体工作流,不仅能直接辅助自动化生成精美幻灯片和动态网站,还构成了端到端交付复杂工作成果的核心竞争优势,帮助用户直接把构想转化为成品。 医疗健康三大支柱与长期记忆的整合诊断价值 (16:36) 在医疗健康领域,Brockman 概述了 OpenAI 的三大支柱布局:第一是每周服务超过 3 亿用户的消费者健康咨询;第二是面向临床医生、具备权威医学文献精准引用能力的专业工具;第三是面向医疗系统与医院的企事业级基础设施,包括与 Epic 电子健康记录(EHR)系统的原生集成。打通这一平台能够消除患者在各独立专科之间手动流转病历的痛点,并有助于精准匹配符合条件的候选患者,化解临床试验招募瓶颈。 此外,跨线程的长期记忆功能将从根本上重塑医疗诊断方式。现代医疗高度细分,专科医生往往各自为政、难以看清全局,而 AI 能够跨越数周乃至数月记录并分析分散的细微症状。Brockman 结合其妻子历时五年辗转多位专科医生、最终由过敏专科医生综合确诊为单一底层遗传疾病的经历指出,具备长期记忆与综合专业知识的 AI,能够有效识别跨系统的异常模式,为长期困于碎片化医疗体系中的患者提供关键诊断线索。 Brockman 的论述勾勒出 OpenAI 从单一会话工具转向系统级智能体基础设施的战略全貌。然而,如何促使习惯于传统对话界面的十亿级用户理解并掌握主动型智能体,以及如何确保深度融入医疗等高风险实体领域时的准确性与合规性,仍是其将前沿技术落地为普惠生产力所必须直面的考验。

Detailed notes — zh

## Background 该视频由频道 TBPN 于 2026 年 9 月 8 日发布在 YouTube 平台。视频简介表明,这是对 OpenAI 联合创始人兼总裁 Greg Brockman 的完整专访,深入探讨了 OpenAI 攻克纳维-斯托克斯千禧年大奖难题、全新模型 Astra 在计算机使用方面的突破、AI 从聊天机器人向主动型智能体的范式演进,以及 ChatGPT 对医疗健康的重塑与公司的未来发展方向。 ## TL;DR Greg Brockman 详细解读了 OpenAI 近期的核心里程碑与战略布局。在基础科学领域,模型攻克纳维-斯托克斯方程标志着 AI 从重组检索信息跃迁至为人类自主创造全新知识;在产品与工程层面,Astra 实现了对人类图形界面的原生计算机操作,彻底告别脆弱的传统 API 连接器,并在 3D 建模及工业设计等日常场景中释放出强大生产力。此外,OpenAI 正全力推进涵盖消费端、临床端与医院系统的 ChatGPT Health 三支柱战略,利用跨线程长期记忆打破传统医疗的专科壁垒。Brockman 强调,OpenAI 已摆脱大公司的冗杂与试错心态,重回极致专注的初创冲刺模式,致力于打造无缝接管复杂细节的主动型数字伙伴。 ## Atmosphere & style 对谈整体洋溢着极客式的技术兴奋与宏大愿景落地后的务实笃定。主持人提问风趣敏锐、直切技术痛点与普通大众的现实关切;Brockman 的回应则沉稳真诚且富有感染力,不仅能从底层的数学证明与系统架构娓娓道来,更深情分享了妻子求医经历等触动人心的真实故事。整场交流在深奥的科学突破与极具烟火气的日常应用之间自如穿梭,听众能够真切感受到一家经历多线探索后的顶尖 AI 机构重新找回如激光般聚焦的初创活力与冲刺脉动。 ## Bulletin - [00:00](https://www.youtube.com/watch?v=qNxuxwb9ksA&t=0s) OpenAI 宣布其模型成功攻克千禧年大奖难题之一的纳维-斯托克斯方程,通过严格反例证明其在特定临界条件下存在奇点,标志着 AI 已具备独立发现人类未知新知识的通用科研能力。 - [05:50](https://www.youtube.com/watch?v=qNxuxwb9ksA&t=350s) ChatGPT 全球周活跃用户数已大幅突破 10 亿大关,其中每周有 3 亿独立用户使用该工具进行医疗健康咨询,成为平台极具影响力的落地场景之一。 - [02:50](https://www.youtube.com/watch?v=qNxuxwb9ksA&t=170s) OpenAI 推出全新模型 Astra 并实现 Computer Use 能力跃迁,摒弃脆弱的定制化 API 连接器,直接跨越桌面图形界面操作 Blender 等复杂专业软件。 - [16:36](https://www.youtube.com/watch?v=qNxuxwb9ksA&t=996s) ChatGPT Health 确立“消费端自诊、临床医生端文献辅助、医院企业端集成 Epic”的三支柱闭环矩阵,全面推动跨专科诊疗与临床试验招募变革。 ## Key takeaways - [00:00](https://www.youtube.com/watch?v=qNxuxwb9ksA&t=0s) 攻克纳维-斯托克斯方程证明 AI 不仅能重组现有数据,更具备自主推导并生成人类全新知识的能力,将直接赋能气流建模、药物设计与深奥科学探索。 - [02:50](https://www.youtube.com/watch?v=qNxuxwb9ksA&t=170s) Astra 标志着 AI 在 Computer Use 维度跨过实用门槛,能够像专业人类一样跨应用直接操作复杂的专业桌面软件(如 3D 建模工具 Blender)。 - [02:50](https://www.youtube.com/watch?v=qNxuxwb9ksA&t=170s) 普通用户未来无需学习复杂的专业工具,统一的智能体将在底层静默调用和调度各项专业软件,端到端交付物理制造或设计成果。 - [05:50](https://www.youtube.com/watch?v=qNxuxwb9ksA&t=350s) AI 交互正经历从繁琐底层微操到主动型智能体的转变,消除手动配置上下文窗口和思考参数的负担,让人类专注于顶层目标制定与把关。 - [05:50](https://www.youtube.com/watch?v=qNxuxwb9ksA&t=350s) ChatGPT Work 在深度知识工作场景引发了智能体采用率的垂直级陡升,推动 AI 彻底从问答式对话转向长流程任务执行。 - [09:10](https://www.youtube.com/watch?v=qNxuxwb9ksA&t=550s) 针对全球庞大的存量尝鲜用户,AI 面临严峻的“功能发现问题”,系统需从被动等待文本输入进化为主动引导连接器配置与任务执行。 - [11:13](https://www.youtube.com/watch?v=qNxuxwb9ksA&t=673s) AI 营销应借鉴苹果公司精准展示具体功能特性的策略,摒弃宏大抽象叙事,转而通过接地气的落地场景激发用户共鸣与自发探索。 - [14:12](https://www.youtube.com/watch?v=qNxuxwb9ksA&t=852s) 图像生成跨越质量阈值后正脱离玩具属性,依靠精准局部控制与多模态同构,重构现实物理设计与商业工作流。 - [16:36](https://www.youtube.com/watch?v=qNxuxwb9ksA&t=996s) ChatGPT Health 布局由大众消费端、医生临床文献辅助端与 Epic 医院系统集成端构成的三支柱体系,构建协同闭环以重塑医疗生态。 - [17:48](https://www.youtube.com/watch?v=qNxuxwb9ksA&t=1068s) 统一的健康数据平台能够打破各专科间的孤岛壁垒,既减轻患者重复同步病历的负担,又可精准匹配临床试验以加速新药研发。 - [19:16](https://www.youtube.com/watch?v=qNxuxwb9ksA&t=1156s) 大模型的跨线程长期记忆与通识全科知识储备,能敏锐识别分散于多个子系统的隐性病理关联,攻克传统专科“盲人摸象”式的误诊与延误痛点。 - [20:51](https://www.youtube.com/watch?v=qNxuxwb9ksA&t=1251s) 早期代理产品 Operator 虽然体验欠佳,但为团队沉淀了关键部署数据,推动代理交互从脆弱的手工 API 连接彻底转向原生的 GUI 屏幕直接操作。 - [22:55](https://www.youtube.com/watch?v=qNxuxwb9ksA&t=1375s) OpenAI 摆脱了大企业式的多头试错模式,重新找回初创团队的敏捷与极度聚焦,促成了 Astra 等多项底层核心技术的快速收敛与爆发。 ## Detailed walkthrough ### [00:00](https://www.youtube.com/watch?v=qNxuxwb9ksA&t=0s) 攻克纳维-斯托克斯方程:AI 产生人类新知识的里程碑 节目开场,主持人热情迎来了 OpenAI 联合创始人兼总裁 Greg Brockman。访谈直接切入当天在科技界引发轰动的重磅消息:OpenAI 宣布其模型成功攻克了数学界著名的纳维-斯托克斯方程(Navier-Stokes equations)。面对主持人的提问——这究竟意味着什么、为何在整个时间线上引发如此热烈的讨论,Brockman 直言这是“现代科学进步与人工智能领域极其重大的一天”。纳维-斯托克斯存在性与光滑性问题是著名的七大“千禧年大奖难题”(Millennium Prize Problems)之一,困扰了人类数个世纪。OpenAI 的模型成功找到了一个反例,严格证明了这些理论方程在特定条件下确实会出现奇点(singularity)甚至走向崩溃。 Brockman 强调,这一证明不仅本身极其优雅精妙,更代表着人类知识边界的实质性拓展。纳维-斯托克斯方程在流体力学中有着广泛的实际映射,涵盖从洋流运动、大气流动到飞机机翼周围的气流与湍流模拟。然而,对他而言,最震撼的不仅是这一具体数学谜题的破解,而是这标志着模型能力进入了全新阶段:AI 已经不再仅仅是检索或重组现有数据,而是能够“创造人类全新的知识”(generate new knowledge),帮助人类解决那些原本遥不可及或需耗费数十年乃至数百年才能解答的深奥难题。 主持人抛出了现实视角的疑问:这项突破究竟会如何影响普通人?它能帮普通人订机票、治愈癌症,还是仅仅沦为 OpenAI 吸引顶尖科研人才的招聘利器?毕竟在大众后院的烧烤聚会上,普通亲友很难对抽象的流体力学方程产生共鸣。Brockman 回应指出,除了直接指导气流与洋流建模等具体工程物理问题外,该突破的真正价值在于底层方法论的迁移与外溢。当 AI 拥有了攻破顶级科学难题的自主推理能力,攻克复杂疾病、设计全新药物等宏大挑战便不再是空中楼阁。这让科学界有底气拥有更广阔的雄心,去挑战以往根本不敢设想的未知领域。 - **核心数学突破**:AI 模型证明了纳维-斯托克斯方程在特定临界条件下存在奇点(singularity),为这一千禧年大奖难题提供了决定性的理论反例与优雅证明。 - **现实映射与科研加速**:直接推动对湍流、大气环流和飞机空气动力学的精细模拟,更重要的是证明了模型具备生成人类未知新知识(new knowledge)并协助顶级科学发现的通用能力。 --- ### [02:50](https://www.youtube.com/watch?v=qNxuxwb9ksA&t=170s) Astra 带来的“计算机使用”跃迁:从 3D 建模到解决日常生活微小痛点 尽管纳维-斯托克斯方程在普通人看来有些遥远,但刚刚过去的周末里,OpenAI 全新模型 Astra 的上线引发了全民狂欢,社交网络上几乎人人都在讨论 Astra 与 3D 创作软件 Blender 的结合。谈及 Astra 的发布反馈,Brockman 感慨万千,表示社区的创造力让他感到既震撼又谦卑。他指出,Astra 的问世标志着 AI 在“计算机使用”(computer use)能力上跨过了一个至关重要的技术门槛——模型如今能够像专业人类一样自如地操作各类复杂的桌面应用程序,并展现出此前从未见过的跨软件协同与构建能力。 在社区涌现的大量应用场景中,用户借助 Astra 将物理空间快速扫描重建成高精度的 3D 模型,甚至直接用它进行实体工业零部件的设计与制造。主持人风趣地提到,周末有人用 Astra 和 Blender 设计了一个装在淋浴地漏上防止头发堵塞的物理过滤结构,并直接将其送去 3D 打印制造,戏称这简直是“淋浴毛发超级智能”(shower hair super intelligence)。Brockman 对此深表赞同,认为这个例子看似琐碎日常,却切中了技术的本质内核:除了仰望星空去解决宏大的宏观挑战,AI 同样应该深入日常生活,赋予普通人以前所未有的“超能力”,让他们能够轻而易举地解决身边真实存在的各类实际问题。 随着极客和重度玩家开始用 Astra 在 Blender 中完整重构房屋并规划装修改造,主持人探讨了技术从硬核极客走向大众消费者的演进路径。许多极客如今购置了配备顶尖显卡的电竞主机或 Mac Mini 来折腾各种工具链的串联,但普通大众甚至根本不知道 Blender 是什么。未来的技术走向显然不是让每个人都去学习复杂的专业软件,而是将这一切能力无缝收拢到一个最简单的输入框中,让强大的工具在底层静默运转。 ```mermaid flowchart TD accTitle: AI 交互与工具调用演进路径 accDescr: 展示从早期低门槛指导到未来端到端统一主动智能体的演进架构 subgraph User["用户意图层 (User Intent)"] A["高维目标输入<br/>(例如:重新规划住宅空间 / 设计排水过滤零件)"] end subgraph Agent["统一智能体层 (Unified Proactive Agent)"] B["ChatGPT 统一界面 / 桌面智能体"] C["长期记忆与持续工作流<br/>(Persistent & Proactive Context)"] B --- C end subgraph Execution["底层工具抽象层 (Invisible Tool Execution)"] D["Blender 自动化脚本 / 3D 建模"] E["Codex 代码生成与执行"] F["复杂桌面应用交互 (Computer Use API)"] end subgraph Output["交付成果 (Real-World Outcomes)"] G["可制造零部件 (3D 打印文件) / 空间渲染方案"] end A --> B B --> D B --> E B --> F D --> G E --> G F --> G ``` --- ### [05:50](https://www.youtube.com/watch?v=qNxuxwb9ksA&t=350s) 从对话框到主动智能体:AI 交互范式的统一与万亿周活时代 Brockman 深入阐述了 OpenAI 对产品形态演进的底层思考。他指出,技术的终极方向是让用户彻底告别繁琐的底层微操,让人类真正“翱翔”起来:用户只需设定顶层目标与战略方向,模型则充当“思维的火箭飞船”或“超强弹簧床”(trampoline / rocket ship for the mind)。人类保留监督权并对最终结果负责,而繁重、重复的执行细节全部交由智能体承载。 在谈到当前的产品格局时,Brockman 梳理了纯聊天(chat)与智能体工作流(agentic workflows)的分野与融合。他透露,ChatGPT 目前每周活跃用户数已“远超 10 亿人”(well over a billion users every week),并且随着团队在医疗健康、教育等基础领域的持续深耕,ChatGPT 的市场份额正在重新强劲攀升。与此同时,自推出 ChatGPT Work 以来,深度知识工作领域的智能体采用率呈现出“近乎垂直的陡峭增长墙”(almost vertical wall of agentic adoption)。Brockman 指出,当前聊天模式与任务型智能体看似并存为两种不同模式,但这只是技术过渡期的产物,OpenAI 正在全力将其整合为一种全新的统一交互范式。 Brockman 总结道,回顾五到十年前人们对 AI 的憧憬,大家期待的从来不是一个需要用户精打细算上下文窗口(context windows)、手动调节思考强度(thinking strength)或纠结该选择哪个具体模型的底层大语言模型。真正的 AI 承诺,应当是一个具备主动性(proactive)、持久性(persistent)、能够真正为你分担工作并“将时间交还给你”的数字伙伴。诸如调用 Blender 这样的底层复杂操作,未来都会彻底隐入系统幕后。 在访谈本段的尾声,主持人提出了著名的“先发者劣势”问题:全球已有数十亿人尝试过早期的 ChatGPT,很多人心中对 AI 的能力认知还停留在当年的初代产品上;而极客们已经在后台让智能体全天候不间断运行,自动监控追踪 SpaceX 火箭发射与延期。面对模型能力的超速迭代,如何不断打破大众的固有认知、向市场证明智能体已经发生质的跃迁,构成了当前先发者面临的新挑战。 - **超大规模用户体量**:ChatGPT 全球周活跃用户已大幅突破 10 亿大关,市场占有率因健康与教育场景的拓展再度提速上扬。 - **智能体工作流爆发**:企业级深度知识工作产品 ChatGPT Work 带来智能体采用率的垂直级陡升,标志着 AI 正式从“问答式对话”向“执行性代理”蜕变。 - **消除底层微操的未来愿景**:未来的交互将彻底摒弃手动配置上下文长度或调节思维链参数等机械操作,由主动型智能体在后台静默协调多种专业软件,端到端交付用户设定的最终成果。 ### [09:10](https://www.youtube.com/watch?v=qNxuxwb9ksA&t=550s) AI 的“功能发现”困境与主动型助手 当前 AI 领域面临着一个严峻的一级课题——“功能发现问题”(Discovery Problem)。普通用户所接触到的无论是标准版 ChatGPT 还是工作版,表面上都只是一个普通的文本框;面对不断迭代的新旧模型,用户很难搞清“为什么这个新文本框比旧文本框更强大”,或者“为什么某些特定场景下还要用旧文本框”。这种产品设计让普通人倍感困惑,而用户的根本诉求只是解决自身问题并“赢回属于自己的时间”,绝非被动成为模型底层细节的专家。破局的关键在于,大模型具备强大的语义理解能力与用户背景上下文认知,它完全应当主动引导用户:“如果你换一种提问方式,或者接入某个连接器、授权某项凭据,我就能替你搞定另一件复杂任务。” 针对存量与潜在用户的再教育蕴藏着不可估量的机遇。目前每周有超过 10 亿活跃用户在使用 ChatGPT,而曾经尝试过该产品的历史用户规模更是高达 10 亿至 15 亿之多。尽管许多早期用户留下了刻板印象,但庞大的用户池使得 OpenAI 能够重新接触他们,证明现在的系统已经能够以颠覆以往的方式解决痛点。一个极具代表性的例证是医疗健康领域:每周已有高达 3 亿人使用 ChatGPT 咨询健康相关问题,切实改变了无数用户及其家人的生活。 - **周活跃用户基数**:每周超过 10 亿人使用 ChatGPT,另有约 10 亿至 15 亿历史尝鲜用户。 - **健康咨询规模**:每周有 3 亿独立用户在 ChatGPT 上进行健康医疗相关的查询。 - **核心交互转变**:从被动的“文本框输入”进化为具备主动建议、引导配置连接器(Connectors)与权限授权的自主助手。 --- ### [11:13](https://www.youtube.com/watch?v=qNxuxwb9ksA&t=673s) 摆脱宏大叙事:像苹果一样聚焦具体场景的 AI 营销 虽然整个 AI 行业都梦想成为“AI 界的苹果”,但许多人在营销理解上陷入了误区,往往只盯着《1984》或“Mac vs. PC”这类宏大的品牌叙事。事实上,苹果公司最强悍的营销手段是日复一日、极其精准地猛砸具体产品特性——例如新相机的某个参数、拟我表情(Mimoji)或 Safari 浏览器的特定功能。由于 AI 的能力边界和应用表面积比传统消费电子大出整整一个数量级,OpenAI 的市场推广不仅需要令人惊叹的 Astra 概念片,更应该在户外广告牌上铺天盖地展示能够立刻为用户省下时间的“具体用例”。 ```mermaid flowchart LR accTitle: 场景化展示与用户探索飞轮 accDescr: 展现从具体可感的落地用例激发用户共鸣,到亲自上手探索并解锁专属隐藏高阶场景的正向循环。 subgraph Showcase["具体场景呈现"] A["展示极具体、接地气的用例<br/>(例如:烛台手绘草图)"] --> B["AI 丰富具象化与物理实物落地"] end subgraph UserAction["用户行动与渗透"] B --> C["用户产生强烈代入感<br/>('我也想要这个效果')"] C --> D["亲自上手尝试"] D --> E["解锁自身潜在的高阶复杂工作流"] end ``` 这种向具体细节聚焦的转变,源于团队在发布 ChatGPT Images 2.5 过程中的深刻反思。以往宣传偏向展示那些极具极客范儿、令人惊叹却略显晦涩的冷门案例,结果发现围观者很难自动举一反三,将其联想到自己的工作流中。相反,当宣传片展示一名用户先手绘了一个粗糙的烛台草图,让 AI 生成一系列极其逼真的视觉设计变体,最后制作出物理世界中实实在在的烛台成品时,观众瞬间就能理解其中的价值。除了具象化营销,另一个关键是养成用户“随时向 AI 询问自身能力”的习惯。对话中举例提到,有位每天依靠 ChatGPT 处理交易备忘录(Deal Memos)的房地产开发商朋友,经常四处打听 AI 到底能不能胜任某项工作;其实最简单的方式就是把手头的系统环境或需求直接丢给模型,询问它究竟该在本地 Codex 线程运行还是云端运行,模型自会给出精准的技术决策。 --- ### [14:12](https://www.youtube.com/watch?v=qNxuxwb9ksA&t=852s) 图像生成质变:跨越专业门槛与多模态技术大一统 当图像模型跨越特定的质量拐点后,整个品类将从“新奇玩具”蜕变为真正能重构现实生产力的工具。以往许多图像生成尝试之所以停留在玩具阶段,是因为只要成品的细节或精度略低于专业标准,它就无法在实际的商业与知识工作中直接采用。要让专业知识工作者、营销人员以及设计师在日常中真正依赖图像模型,系统必须具备四大支柱:极其精准的局部编辑控制能力(Precise Edit Control)、闪电般的生成速度、天马行空的创意多样性,以及人机之间流畅无缝的交互往复。 图像模型带来的下游现实世界连锁反应是不可估量的。如果用户能够拍下一处现实空间的物理照片,并随意生成各种改造风格的逼真变体,这将直接促成无数物理实体的建造与设计决策。而在日常办公层面,图像能力也正在重塑幻灯片制作与精美网站构建等基础工作流。OpenAI 的长期蓝图并非把图像作为一个孤立的画图工具,而是将其与语音(Voice)、代码生成(Coding)等技术深度打包为一个统一的智能体,让人人都能将脑海中的构想瞬间落地成真。 - **专业采纳的前提**:必须跨过“可用性质量阈值”,单纯的概念生成不足以满足知识工作与营销的交付标准。 - **核心交互要素**:高精度的编辑控制、生成速度、结果多样性,以及连续的人机协作微调。 - **系统级融合**:图像并非孤立存在,它与代码生成、语音处理同构,共同赋予下游产品(如自动化网页制作、PPT 排版)无缝生成图文代码混合资产的能力。 --- ### [16:36](https://www.youtube.com/watch?v=qNxuxwb9ksA&t=996s) 医疗健康的系统性革命:ChatGPT Health 的三支柱体系 在医疗健康领域,大众普遍的认知仍停留在让模型解读体检化验单或综合睡眠监测数据的初级阶段。但 OpenAI 对 ChatGPT Health 的战略构想远比这更深邃、更具系统性。整个医疗战略并非单点突破,而是构建在一个由三大独立发力又彼此高度协同的支柱矩阵之上,试图从个体、医护人员到体制系统全面重构现代医疗健康体验。 ```mermaid flowchart TD accTitle: ChatGPT Health 三支柱战略架构 accDescr: 描述面向消费端、临床医生端以及医院企业端的三大支柱,通过底层协同共同推动医疗体系变革。 subgraph Pillars["ChatGPT Health 三大支柱"] direction LR P1["面向普通大众消费端<br/>(每周 3 亿健康查询需求)"] P2["自底向上切入临床医生端<br/>(深度调优、附带专业文献严谨引用)"] P3["医院与机构企业级接入<br/>(深度集成 Epic 等核心医疗系统)"] end subgraph Flywheel["协同放大效应"] P1 <--> Synergy["多端数据与流程闭环"] P2 <--> Synergy P3 <--> Synergy Synergy --> Transform["全方位重塑美国乃至全球医疗健康体验"] end ``` 第一大支柱是面向广大普通大众的消费端,每周稳定承载着 3 亿用户的日常医疗答疑与健康管理;第二大支柱是自底向上渗透的临床医生端,专为医护工作者深度微调,具备严谨的直接医学文献引证能力,成为医生值得信赖的诊断与研究副手;第三大支柱则是面向医院与医疗机构的企业级销售,目前已实现与医疗行业核心软件巨头 Epic 的底层系统集成。当这三大支柱各自建立起足够坚实的飞轮并产生交叉协同效应时,这种闭环将不仅提升单次就诊效率,更具备全方位革新美国乃至全球医疗健康体系的巨大能量。 - **第一支柱(消费端)**:服务于广泛的大众日常健康诉求,每周解答 3 亿用户的医疗疑问。 - **第二支柱(临床端)**:采用自底向上的推广模式,专为临床医生量身定制,输出内容附带严格的专业医学文献引用。 - **第三支柱(企业级与医院生态)**:直接向大型医疗中心和医院体系提供企业级解决方案,实现与 Epic 等主流电子病历(EHR)系统的原生集成。 - **核心协同愿景**:三大支柱相辅相成,打通患者自诊、医生辅助决策与院端系统的全链路壁垒。 ### [17:48](https://www.youtube.com/watch?v=qNxuxwb9ksA&t=1068s) 重塑医疗平台与临床试验:从分散看诊到 AI 赋能患者 格雷格·布罗克曼(Greg Brockman)深入探讨了医疗体系中患者承受的巨大隐形成本。在当下的医疗环境中,患者在不同专科医生之间辗转时,必须亲自携带和同步自己的病历,一遍又一遍地向新医生陈述病情,往往“无论愿意与否,患者自己反而成了那个必须承担最终决策责任的‘主治医生’”。布罗克曼指出,如果所有医疗数据能在统一的平台上顺畅共享,医疗体验将迎来彻底变革。此外,临床试验患者招募长期以来都是新药研发的最大瓶颈之一,如果患者愿意信任并交付健康数据,平台就能精准匹配符合特定临床试验且能从中受益的患者,这不仅造福个体,也将推动全球医学发展。 布罗克曼将 OpenAI 的医疗愿景总结为“打造全球最好的医疗平台,将医疗健康真正带入 AI 时代”。他坚信这一变革将从根本上提升无数人的生活质量,而且这种积极影响目前已经在真实世界中发生。在关于 ChatGPT 的众多反馈中,他最动容的故事往往来自那些直言“ChatGPT 帮我救了自己或家人的命”的用户——很多患者在面临复杂病症时,通过 ChatGPT 复核医生的诊断和方案,理解了晦涩的医学解释,甚至据此向医生提出质疑并推动重新评估,最终获得了极佳的治疗结果。布罗克曼强调,AI 在健康领域的应用目前才刚刚触及冰山一角,这是 AI 技术最具善意与潜力的落地方向之一。 - **医疗数据孤岛**:传统模式要求患者自行跨专科流转病历并重复解释病情,统一平台将彻底打通这一环节。 - **新药研发提速**:利用集中式数据解决临床试验招募的瓶颈难题,精准匹配潜在受益人群。 - **赋能患者知情权**:用户日常使用 ChatGPT 交叉验证医生建议并深度理解病情,真实救命案例层出不穷。 --- ### [19:16](https://www.youtube.com/watch?v=qNxuxwb9ksA&t=1156s) 记忆功能与跨专科诊断:打破“盲人摸象”的医疗痛点 对话随后转向了大模型“长期记忆(Memory)”能力与医疗健康的交汇点。主持人指出,当 ChatGPT 能够在全新对话中自动关联数周前讨论过的碎片信息时,它可能会发现人类需要花费数年才能察觉的隐秘病理模式,从而提醒用户看似不相干的症状其实同属一个潜在病症。布罗克曼对此深表赞同,并首次公开分享了身边的真实故事:他的妻子曾经历了一场长达五年的漫长求医之路。 在那五年里,他的妻子辗转咨询了无数专科医生,但每位医生都像“盲人摸象”一样只检查和处理自己负责的局部器官或系统。直到最后,一位过敏专科医生打破了专科壁垒,敏锐地指出她所有的分散症状其实彼此关联,最终确诊为一种累及全身所有子系统的罕见遗传性疾病。布罗克曼感慨道,现实中有太多人长期受困于类似复杂的全身性病症,却受制于专科细分而永远无法得到确诊。这也正是 AI 能够发挥巨大价值的所在——它不仅能长期、跨领域地全面了解一个人的日常生活,还能同时扮演精通所有医学专科的资深专家,打破专科壁垒完成跨领域的全景诊断。 ```mermaid flowchart TD accTitle: 医疗诊断模式对比 accDescr: 对比传统专科割裂的盲人摸象模式与AI多专科整合模式 subgraph Traditional["传统专科诊断:盲人摸象"] A["专科 A:仅看局部病症"] B["专科 B:孤立处置用药"] C["专科 C:缺乏横向沟通"] A & B & C --> D["患者承担整合成本 / 诊断延误数年"] end subgraph AIDriven["AI 全科记忆整合模式"] E["跨线程长期记忆跟踪"] F["融通全领域医学专科知识"] E & F --> G["识别多系统隐性关联,精准确诊全身性疾病"] end ``` --- ### [20:51](https://www.youtube.com/watch?v=qNxuxwb9ksA&t=1251s) 从 Operator 的探索到 Astra 的计算机使用突破 主持人就 OpenAI 早期推出的代理产品“Operator”发问,询问它究竟是一次失败的尝试、一条旁支探索,还是后来计算机使用(Computer Use)技术演进的必经之路。布罗克曼坦率回应,一切都关乎“时机选择”与“迭代部署(Iterative Deployment)”的哲学。他承认最初的 Operator 确实处于“能力阈值之下(Below Threshold)”:作为一个基于云端运行的计算机交互系统,它速度缓慢、准确率欠佳,使用过程甚至相当痛苦,虽然部分用户从中获得了价值,但产品整体尚未达到及格线。 然而,OpenAI 最显著的基因就是愿意在真正重要的方向上进行超长期投入,并耐得住性子“啃硬骨头”。团队花费大量精力逐项攻克长期积累的庞大问题清单,最终实现了技术跃迁。布罗克曼将以往的代理方案形容为“通过连接器(Connectors)使用计算机”——依赖极其繁琐的手工编码接口,这与人类使用电脑的方式截然不同。而人类计算机界面(GUI)天生是为人眼和人手设计的,一旦 AI 掌握了直接通过屏幕和界面操作计算机的能力,就能胜任人类在电脑上能做的一切事情。从 OpenAI 创立伊始,打造一个能像人一样操作界面的 AI 就是团队的梦想,而 Astra 终于让这一设想变为现实。 - **Operator 的技术定位**:早期的云端交互实验,虽然速度慢、准确度低、体验痛苦,但为团队提供了不可替代的真实世界部署数据。 - **交互范式转变**:从依赖脆弱易碎的定制化 API 连接器,彻底转变为原生理解人类 GUI 的直接计算机使用(Computer Use)。 - **长期主义兑现**:通过系统性清理庞大 Bug 清单与长线底层研发,在 Astra 上全面兑现了从建厂之初就确立的计算机操作构想。 --- ### [22:55](https://www.youtube.com/watch?v=qNxuxwb9ksA&t=1375s) 从大厂模式重回初创聚焦:Astra 背后的全力冲刺 主持人在对谈尾声总结道,Astra 标志着模型基础能力、原生计算机使用、实时语音等多条长期技术路线在最恰当的时机汇聚融合。他特别提到 OpenAI 在文化形态上的显著反转:如果说前一年的 OpenAI 行事风格有些趋于大型科技公司(Hyperscaler)——分散开多条产品线,抱着“哪怕只有 5%、10% 或 20% 的成功率也无所谓”的心态做实验;那么今年,整个公司似乎全面切换回了极致专注的“真正初创模式(Startup Mode)”,全员心往一处想、劲往一处使,重新找回了不可思议的交付速度与增长动力。 布罗克曼十分认可这一评价。他表示,让一家体量已经相当庞大的公司从大企业官僚化运作重新调头,回归如初创团队般的敏捷与凝聚力,是一项极其艰巨却又令人自豪的壮举。这是整个 OpenAI 团队无数员工共同拼搏的结果。布罗克曼强调,公司当前拥有极高的“激光般聚焦(Laser Focused)”,全团队做出的每一个决定、交付的每一项工程,都在紧密服务于最终的通用人工智能使命。对谈在双方对 Astra 及未来智能体演进的期待中圆满结束。 ## Notable quotes > [00:00](https://www.youtube.com/watch?v=qNxuxwb9ksA&t=0s) 现代科学进步与人工智能领域极其重大的一天 — Greg Brockman > [00:00](https://www.youtube.com/watch?v=qNxuxwb9ksA&t=0s) 创造人类全新的知识 — Greg Brockman > [02:50](https://www.youtube.com/watch?v=qNxuxwb9ksA&t=170s) 淋浴毛发超级智能 — 主持人 > [05:50](https://www.youtube.com/watch?v=qNxuxwb9ksA&t=350s) 思维的火箭飞船 — Greg Brockman > [05:50](https://www.youtube.com/watch?v=qNxuxwb9ksA&t=350s) 超强弹簧床 — Greg Brockman > [05:50](https://www.youtube.com/watch?v=qNxuxwb9ksA&t=350s) 近乎垂直的陡峭增长墙 — Greg Brockman > [05:50](https://www.youtube.com/watch?v=qNxuxwb9ksA&t=350s) 将时间交还给你 — Greg Brockman > [17:48](https://www.youtube.com/watch?v=qNxuxwb9ksA&t=1068s) 无论愿意与否,患者自己反而成了那个必须承担最终决策责任的‘主治医生’ — Greg Brockman > [17:48](https://www.youtube.com/watch?v=qNxuxwb9ksA&t=1068s) 打造全球最好的医疗平台,将医疗健康真正带入 AI 时代 — Greg Brockman > [17:48](https://www.youtube.com/watch?v=qNxuxwb9ksA&t=1068s) ChatGPT 帮我救了自己或家人的命 — Greg Brockman > [20:51](https://www.youtube.com/watch?v=qNxuxwb9ksA&t=1251s) 通过连接器使用计算机 — Greg Brockman > [22:55](https://www.youtube.com/watch?v=qNxuxwb9ksA&t=1375s) 激光般聚焦 — Greg Brockman ## Mentioned Greg Brockman, OpenAI, 纳维-斯托克斯方程 (Navier-Stokes equations), 千禧年大奖难题 (Millennium Prize Problems), Astra, Blender, Mac Mini, ChatGPT, ChatGPT Work, SpaceX, ChatGPT Images 2.5, Codex, ChatGPT Health, Epic, Operator, Apple ## Video description This is our full interview with OpenAI Co-Founder and President Greg Brockman. We discuss how OpenAI solved the Navier-Stokes Millennium Prize problem, what Astra reveals about the future of computer use, why AI is shifting from chatbots to agents that can actually do work for you, how ChatGPT could transform healthcare, why image generation is unlocking entirely new applications, what OpenAI learned from Operator, and where AI goes from here. TBPN is made possible by: Ramp - https://ramp.com Public - https://public.com Cisco - https://www.cisco.com Console - https://www.console.com CrowdStrike - https://www.crowdstrike.com Figma - https://www.figma.com MongoDB - https://www.mongodb.com NYSE - https://www.nyse.com Railway - https://railway.com Shopify - https://www.shopify.com/ Codex - http://openAI.com/codex Sign up for TBPN’s daily newsletter at TBPN.com Follow TBPN: https://TBPN.com https://x.com/tbpn https://open.spotify.com/show/2L6WMqY3GUPCGBD0dX6p00?si=674252d53acf4231 https://podcasts.apple.com/us/podcast/technology-brothers/id1772360235 https://www.youtube.com/@TBPNLive [Source](https://www.youtube.com/watch?v=qNxuxwb9ksA)

Source quotes

[0:00] Greg Brockman: 现代科学进步与人工智能领域极其重大的一天 [0:00] Greg Brockman: 创造人类全新的知识 [2:50] 主持人: 淋浴毛发超级智能 [5:50] Greg Brockman: 思维的火箭飞船 [5:50] Greg Brockman: 超强弹簧床 [5:50] Greg Brockman: 近乎垂直的陡峭增长墙 [5:50] Greg Brockman: 将时间交还给你 [17:48] Greg Brockman: 无论愿意与否,患者自己反而成了那个必须承担最终决策责任的‘主治医生’ [17:48] Greg Brockman: 打造全球最好的医疗平台,将医疗健康真正带入 AI 时代 [17:48] Greg Brockman: ChatGPT 帮我救了自己或家人的命 [20:51] Greg Brockman: 通过连接器使用计算机 [22:55] Greg Brockman: 激光般聚焦

Source quotes

[0:00] Greg Brockman: models have reached the capability to generate genuinely new human knowledge and solve problems previously considered out of reach. [3:19] Greg Brockman: Astra represents a distinct new threshold in computer use where AI directly interacts with complex software applications. [5:50] Greg Brockman: rocket ship for the mind [8:14] Greg Brockman: discovery problem [14:50] Greg Brockman: crossing key capability thresholds unlocks fundamentally new applications that are hard to predict in advance. [14:50] Greg Brockman: create anything that you imagine [16:36] Greg Brockman: one part of the elephant [20:51] Greg Brockman: below threshold [20:51] Greg Brockman: Astra, by contrast, interacts with computers visually and functionally the exact same way humans do, unlocking universal interaction across any software designed for people.

Original transcript

[0:00] We have Greg Brockman, the co-founder [0:02] and president of OpenAI with us. Welcome [0:04] to the show, Greg. How are you doing? [0:06] >> Doing great. Thank you for having me. [0:07] >> Thanks for hopping on. Uh huge day. Can [0:10] we start with the with the math [0:12] advances? What is what what is [0:14] happening? Why is this important? Uh [0:16] there's a lot of back and forth in the [0:18] timeline, but I'd love for you to just [0:19] set the table for us on what actually [0:21] happened with uh Navier Stokes today. [0:24] Well, uh it's always a huge day uh in uh [0:28] AI and modern scientific progress, I [0:30] would say. Yeah. Today we announced that [0:33] our model had solved the Navier Stokes [0:37] uh problem. Uh that we found a a counter [0:41] example or a sort of proof that you can [0:43] actually that these these uh theoretical [0:46] equations do have a singularity or kind [0:48] of break down under certain [0:50] circumstances. And this is a problem [0:51] that has been open for a very long time. [0:53] It's one of the seven millennium [0:54] problems which are kind of some of the [0:56] deepest most important problems in [0:58] mathematics and I I think that the [1:01] problem itself is important right this [1:02] is new knowledge for humanity that the [1:04] proof itself is actually very elegant [1:06] and beautiful and I think that there's a [1:08] lot to learn from it and the the [1:11] equations have lots of application and [1:13] fluid dynamics in other areas but to me [1:15] what's even more important is about what [1:17] this represents about where we are in [1:19] terms of model capabilities and the fact [1:21] that we can actually generate new [1:22] knowledge that we can learn from these [1:24] models to and have them help us solve [1:26] problems that are otherwise outside of [1:28] reach or would take us a very long to [1:29] solve. [1:30] >> Yeah. I mean, where should I actually go [1:32] with this? Is this going to help me book [1:33] a flight? Is this going to help me cure [1:36] cancer? Is this just going to help you [1:38] recruit researchers who are fascinated [1:40] by this stuff? Uh because I think that [1:42] there's this is, you know, taken over [1:44] the technology world. Uh but I imagine [1:47] that this will not be something that [1:48] gets talked about at backyard barbecues [1:51] with friends and family that are three [1:53] clicks removed from outside of [1:54] >> Yeah. Yeah. [1:55] >> Well, look, I think that there's first [1:57] of all the applications of this specific [2:00] result or the equations themselves, [2:02] right, which are things that let us [2:03] better understand phenomena from ocean [2:05] currents to air flow around aircraft. [2:07] Sure. Uh around, you know, turbulence [2:09] and things like that. But it's really [2:10] about the broader insights and methods [2:13] that can help scientists and [2:14] mathematicians further accelerate their [2:16] research. And I think that again [2:18] representative of if we have models that [2:20] can help solve this kind of problem then [2:23] what happens from here like what other [2:26] problems that are immediately [2:28] applicable. And I think that talking [2:30] about curing diseases and new medicines [2:32] we're going to be able to develop, all [2:33] of that starts to become much more real [2:35] when you have models that are at this [2:37] level of assistance and capability. And [2:40] I do think that there are going to be [2:41] real changes to to think about in terms [2:44] of we can have so much more ambition [2:46] with the kinds of of challenges that we [2:49] can hope to tackle now. [2:50] >> Yeah. I I mean I think uh even even if [2:53] this doesn't break through to the [2:56] broader uh the broader world uh the [3:00] weekend definitely will because it [3:02] seemed like everyone was talking about [3:04] Blender, talking about Astra building [3:06] stuff. Uh take us through the launch of [3:09] Astra, what the feedback has been, what [3:11] you've learned. It seemed like there [3:12] were a couple resets, the model scaled [3:14] very well. Uh how was this launch [3:17] different than previous launches? [3:19] Well, first of all, I've just been blown [3:21] away by the community reaction to Astra. [3:23] It's been really amazing and very [3:26] humbling, honestly, to see all the [3:28] creativity and the different ways that [3:30] people have been applying the model. And [3:31] I think that it's very clear that we've [3:33] reached a new threshold of computer use. [3:36] So, this model is able to really work [3:39] with different kinds of applications in [3:41] a way that was not previously possible. [3:43] And people are taking full advantage of [3:45] that fact and really thinking about how [3:47] to create. I lots of people showing off [3:49] 3D creations and [3:51] >> mapping out physical locations and [3:53] turning them into into these 3D models [3:55] and thinking about can you use this for [3:58] >> design of physical parts. Someone talked [4:00] about how they were designing some [4:02] mechanic for catching hair in a shower [4:04] drain and that they were able to [4:07] >> super cool, right? That that they're now [4:08] able to actually manufacture that [4:10] >> shower hair super intelligence. Yeah. [4:12] No, that stuff's so mundane, but it's so [4:14] important. I I feel like uh a lot of [4:16] this stuff gets lost. Right. [4:18] >> Ex. Exactly. And I think there's a core [4:20] there that's very important, which is [4:21] that we are talking about these grand [4:23] challenges sometimes or very esoteric [4:25] applications, but really the everyday [4:28] the number of problems that you have in [4:29] your life that you would love to solve. [4:32] It's now possible, right? That that [4:33] we're really trying to empower the [4:34] individual to make it so that you can be [4:37] you can have superpowers, you can [4:39] accomplish more. And I think that that [4:41] you know, really trying to benefit [4:43] people, empower people, build tools that [4:45] can really help you and help you in your [4:47] your daily life. That's all part of what [4:49] we're we're we're working on. [4:51] >> So, yeah, I mean, it seems like a huge [4:54] number of people in uh in tech uh [4:57] effectively rebuilt their entire house [4:59] in Blender and planned a remodel this [5:02] weekend. Uh thanks to Astra and but I am [5:04] wondering about the merge and how you [5:06] bring together codecs, chatt work, [5:10] chacht on desktop. I have a gaming PC [5:13] now with a Nvidia card in it. I have a [5:15] Mac Mini. Like I have all these things [5:17] and I can imagine that I'm just I'm [5:19] doing that unnecessary or like it's fun [5:21] for me, but uh that early adopter work [5:23] of going and unhobling it a little bit [5:26] here and there, but in the future this [5:28] will all just be tucked in one, you [5:30] know, prompt box and it might build a 3D [5:33] Blender model for to answer my question [5:35] of should I remodel my house or not. Um, [5:38] but how do you see the capabilities that [5:40] we saw on display from sort of light [5:42] power users over the weekend actually [5:44] making their way into uh consumers who [5:47] might not even know what Blender is. [5:50] >> Well, I think you're exactly right that [5:52] we really want to shift these tools from [5:55] requiring kind of low-level [5:58] sort of [6:00] >> access or guidance to really having the [6:03] human be able to fly, right? to really [6:05] be empowered for you to be able to set [6:06] the goals and the objectives and that [6:09] you still should feel like you can get [6:11] into those details and you can [6:13] understand them. you can provide that [6:14] oversight because ultimately you should [6:16] feel accountable for the outcomes but [6:18] you have this this absolute amplifier [6:20] right like a trampoline or like a you [6:22] know rocket ship for the mind like [6:23] however you want to to to analogize it [6:26] and I think what that means at a [6:27] practical level so first of all this [6:29] year we've been really seeing this shift [6:30] from just pure chat use cases to gentic [6:34] use cases but I would also keep in mind [6:35] that chat is alive and well I mean we're [6:37] we're now well over a billion users [6:39] every week that you can see that the [6:41] market share of chatbt is starting to [6:43] climb once again because we've been [6:44] investing so hard in in so many use [6:47] cases that are important for people in [6:49] education and health and a variety of [6:51] other areas and then at the same time [6:53] these productivity deep knowledge work [6:55] use cases those are really taking off [6:56] we've had this like almost vertical wall [6:58] of agentic adoption since we launched [7:00] chat GBT work and I think that the fact [7:02] that these are two distinct modes that [7:04] that is actually a point in time that is [7:06] something that we're continuing to unify [7:08] and merge and that we're starting to see [7:10] that there's a new emerging form factor [7:12] for how people want to consume AI. And I [7:14] think that it's almost like that the [7:16] promise of AI has always been that you [7:19] have something that you can talk to and [7:21] really delegate work to that's proactive [7:23] and persistent. And that I what we were [7:26] promised if you were to rewind five 10 [7:28] years ago was never a low-level language [7:31] model. You have to think about context [7:32] windows and you have to select thinking [7:34] strength and you have to select [7:35] different models. Like none of that none [7:37] of that is is the future. And so I think [7:39] that we're moving towards real [7:41] amplification, real giving you time [7:43] back, real having computers that are [7:46] able to operate according to your goals, [7:48] to your desires. And I think that that [7:51] is a core of it. We're developing this [7:53] safely. That's that's one of the core [7:55] commitments that that we make and how we [7:57] think about this. Um but but we really [7:59] see the power of these tools starting to [8:02] really um really start to increase in [8:05] terms of what people are capable of and [8:06] that under the hood utilizing tools like [8:09] blender so that that is almost a detail [8:11] that fades into the background is [8:12] absolutely the direction of travel. It [8:14] feels like in AI particularly there's [8:16] been a almost like a first mover [8:18] disadvantage in that billions of people [8:22] have tried Chad GBT and and some [8:24] percentage of them tried it for the [8:26] first time and have a certain impression [8:28] of the product and what it can do and [8:30] then you know even in the last few weeks [8:31] there's been new agents and and products [8:33] that come online and people try it and [8:35] their mind is just completely blown and [8:37] I think it's funny because I'm like well [8:39] as somebody who's like you know trying [8:41] to get the absolute max out of ChatG [8:43] GBT. I'm like, well, I've been running [8:44] like, you know, I've had like an agent [8:47] running that, for example, will tell me [8:48] every time a SpaceX launch is going to [8:50] happen and if it gets delayed, right? [8:51] These sort of like persistent agents [8:53] that are running in the background. Um [8:55] and but but strategically I feel like [8:57] it's a it's a new kind of challenge [9:00] because you have this the as capability [9:02] has been been scaling [9:05] first movers need to be almost like [9:07] constantly reminding the the market of [9:10] um all these just like new ways to use [9:13] >> overhang. Yeah, we we think about this a [9:16] lot and I think that there's this [9:17] discovery problem that we as a field [9:21] need to really encounter in a first [9:22] class way and we haven't done it fully [9:24] yet, but I think we have a real shot at [9:27] solving it better than any product [9:29] before because [9:31] >> the the thing that that right now we [9:33] kind of rely on. You think about chat [9:35] GBT chat GBT work. These are both text [9:37] boxes, right? And it's like, well, this [9:39] new text box is way more powerful than [9:40] the old text box. And but oh, oh, there [9:42] are some reasons that you still want to [9:43] use the old text box. It's not, you [9:45] know, it's like far too confusing. [9:47] People just want something that can help [9:49] them solve their problem. The whole [9:50] point is to get your time back, not for [9:51] you to have to go and become an expert [9:53] in all these these internal details. But [9:55] at the same time, we also have a model [9:57] that understands what you're trying to [9:58] accomplish, right? That you're [10:00] explaining to it, here's what I want. It [10:01] has a lot of context on you. And so it [10:03] should also be able to proactively say [10:05] to you, hey actually if you ask me this [10:07] other way or if you add added this [10:09] connector or if you authorize me to do [10:11] this or if you you know hook up your [10:14] credentials in this in this way I can go [10:16] and do this other thing for you and so [10:18] we're thinking a lot about that [10:19] self-nowledge that onboarding process [10:21] and I think that is a huge huge [10:23] opportunity and I think that there is [10:25] both the the disadvantage that you cite [10:27] of people tried it they form an [10:29] impression and it's changed that it's [10:30] something new but there's also an [10:32] advantage I chat chatbt like over a [10:34] billion users every week like that is [10:36] unique no one has that kind of use on on [10:39] these on these models and I think that [10:41] the number of people who have tried [10:42] chatbt before I think it's it's another [10:45] you know billion billion and a half [10:46] something like that and so that's a huge [10:49] opportunity as well for us to go back to [10:50] those users and say hey we can now solve [10:53] the problem for you we can now help you [10:55] in ways that you didn't see before and I [10:57] think that it's it's true it's real you [10:59] look at how many people use chat for [11:00] health 300 million people every single [11:03] week with health queries, right? And [11:04] that that's really making a difference [11:05] in people's lives and that of their [11:07] loved ones. And so we have such [11:08] opportunity. [11:09] >> Can you stay there with with health and [11:10] and and explain where [11:12] >> one note before that? Something that I [11:14] think is really interesting and I think [11:16] something that OpenAI can can do a lot [11:18] better is like when people talk about [11:20] like everyone in AI wants to be like the [11:22] Apple of AI from a marketing standpoint. [11:24] When they when you think like Apple [11:26] marketing, you're thinking like Mac [11:28] versus PC or you're thinking 1984, these [11:30] big branding campaigns. But the actual [11:33] thing that Apple does really really well [11:35] with marketing is they just hammer [11:37] really really specific details about [11:39] their products, right? They're like [11:40] >> they're advertising the new camera. [11:42] They're advertising Mimoji, right? [11:44] They're advertising like [11:46] >> certain features in Safari, right? And [11:48] so it's like with AI, the surface area [11:50] of like things that you need to [11:52] communicate is actually like an order of [11:54] magnitude greater because it can do so [11:56] many different things. And so I think [11:57] there's such an opportunity [11:58] >> um for the company to focus advertising. [12:02] The brand campaigns are awesome and like [12:04] the the launch video for Astro was [12:05] amazing, but it's like there should be [12:07] billboards running of like very specific [12:09] things that Chach BT can do to give you [12:11] back your time. Um [12:13] >> yes, this this has actually been a real [12:15] sort of realization or just like [12:17] something that I have really come to [12:18] over the course of of of this year. And [12:21] if you look at even for example the you [12:23] know we just announced chat GBT images [12:25] 2.5 [12:26] >> and if you look at the launch video [12:27] there the thing that I love about it is [12:29] it shows here's someone creating an [12:32] image and here's like a bunch of [12:34] different variations of it and then [12:36] here's them taking their favorite one [12:38] and having it in the world. like someone [12:40] said, "Here's a cool like little sketch [12:42] of a candle holder." You see an awesome [12:43] visualization of it and then you see the [12:45] physical candle holder and you're just [12:47] like that's what you want, right? It's [12:48] like you it speaks to you immediately. [12:50] And I think that that really showing [12:52] people here's a use case. And the thing [12:54] that was also a little surprising to me [12:55] is that we've sometimes highlighted [12:57] esoteric use cases, something that [12:59] appeals to someone in particular and [13:01] it's amazing for that person, but people [13:03] don't then say, "Oh, because it's this [13:05] powerful, I can also do this other [13:07] powerful thing I've been waiting on." [13:08] like that connection is is is is [13:10] something that is less sort of easy to [13:12] make than I than I'd realize and it [13:14] makes sense. What you want is to for [13:16] there to be use cases where people say I [13:17] actually want that particular thing now [13:19] let me go try it myself and then from [13:21] there you start exploring and you start [13:22] to find I actually do have this powerful [13:24] use case that I didn't even realize was [13:26] tip at the time. [13:27] >> Yeah. Studio is probably like the best [13:29] example of that working really really [13:30] well. [13:30] >> The other thing is is reminding people [13:33] to ask the AI what it's capable of. [13:35] Yeah, like I was I was having lunch with [13:37] a buddy who's a real estate developer [13:38] and he is using chat all day long for [13:42] different like deal memos and to [13:44] understand like projects that he's [13:46] working on all this stuff and he'll ask [13:47] me he'll ask me all the time can can [13:49] catch GPT do this or that and I'm like [13:51] I'm happy to I'm happy to answer you but [13:53] like you have the thing that will just [13:55] explain exactly how to do the thing that [13:57] you want to do or or maybe not but it [14:00] probably can. [14:00] >> Yeah, I I I did the same thing. I was [14:02] kicking off this Blender thing and I was [14:03] like, should I run this as a local [14:06] codeex thread or in the cloud? Let me [14:08] know which one's better based on my [14:10] system and it gave me a good answer and [14:11] I was able to go for it. [14:12] >> On on images, uh when when images 2 came [14:16] out, I had some moments where I thought, [14:18] okay, images is solved. Like where do [14:20] you where do you think images actually [14:22] go as a category? because it felt uh [14:25] like this has been something that has [14:26] maybe oneshoted me more than anything [14:28] else. specifically with like when it [14:30] when it released, I was I was um [14:33] >> uh spending hours like like on a [14:36] Saturday trying to design furniture, [14:38] right? And just going through like you [14:40] know hundreds and hundreds of prompts. [14:42] But how how far can image models go and [14:46] where are they going and what are the [14:47] ways in which you think they can um they [14:50] can be applied? We were talking earlier [14:51] too about the downstream impact of of [14:53] image models. If you can take, you know, [14:56] a a physical space somewhere and take a [14:58] picture of it and imagine it as all [15:00] these other variations, there's so much [15:02] like real world activity that will be [15:04] driven from that because people can see [15:06] this thing. [15:06] >> Yeah. [15:07] >> Visually and say like I now I want to go [15:09] make that reality which I think is [15:10] really cool. [15:11] >> Well, I think that's exactly the right [15:13] way to think about it is as you hit new [15:14] thresholds of capability, my experience [15:17] has always been that fundamentally new [15:19] applications become unlocked in ways [15:20] that you almost wouldn't have thought [15:22] about ahead of time. And so I think that [15:25] within for example knowledge work, [15:27] professional work, marketing, all those [15:29] areas, you just need to be above a [15:31] quality threshold. If you're below it, [15:32] it's a cool concept, but you can't [15:34] actually use the final material, right? [15:35] That that then means that you you [15:37] haven't really solved the problem. and [15:39] that having precise edit control, being [15:42] fast and really being creative and [15:45] having a diversity of different results [15:46] and also being able to [15:48] >> have this this good interplay back and [15:50] forth with a person. I think that that [15:52] really unlocks whole new use cases and I [15:54] think there's a huge market there and [15:56] even for example the kinds of things you [15:58] may not think of naively but actually [16:00] start to be really important [16:02] applications we're seeing happening is [16:04] slide creation or making awesome [16:06] websites, right? Being able to have that [16:08] image generation capability in the [16:10] middle is something that's very unique [16:11] to OpenAI uh relative to to some of our [16:14] competitors. And I think that you're [16:15] able to then produce much better [16:16] artifacts downstream. And so we really [16:19] view images, we view voice, we view [16:22] coding, all of these capabilities as one [16:26] package that are going to come together [16:27] to create an AI that empowers you. That [16:30] means you can create anything that you [16:31] imagine. And I think it's going to be [16:34] something that's just unlike anything [16:35] out there. Let's go back to health. I [16:38] think most people already are aware that [16:41] you can synthesize some lab data with [16:43] some sleep scores, but your vision that [16:46] you laid out recently for where that [16:49] product goes is much more complex, much [16:51] deeper. So, uh tell me where uh ChatBT [16:55] Health is going in the future. [16:58] >> Well, I would think of it as there are [17:00] three sides to what we do on health. [17:02] There's the consumer side again 300 [17:04] million people every week with health [17:06] queries. [17:07] >> There's the clinician side which is [17:09] bottoms up [17:10] >> and that's really about think of it a [17:13] chatbt that's really tuned for [17:14] clinicians that gives them direct [17:16] citations to medical literature things [17:18] like that. [17:19] >> There's a third pillar which is the [17:21] enterprise side of selling directly to [17:23] hospitals and them enabling it. And you [17:25] can see things like we have an [17:26] integration within Epic and really [17:28] trying to bring each of these three [17:32] pillars the best possible service [17:34] independently. But you think about as [17:36] those really build momentum that you [17:38] actually are able to get synergies [17:39] across them, right? That there's [17:41] something that actually makes the health [17:42] experience and the ability to really [17:44] transform health care in America and the [17:46] world on the table because there's so [17:48] many think about how much work you as a [17:50] patient have to do. If you're talking to [17:52] different specialists, you have to carry [17:53] your medical record from one to the [17:55] other. You have to explain again here's [17:57] the issue and that ultimately you're on [17:58] the hook. You're the doctor who has to [18:00] make the decision whether you like it or [18:01] not. And actually being able to have [18:02] just good sharing of of that information [18:05] across different providers that becomes [18:06] possible if everyone's on one platform [18:08] or think about clinical trial [18:09] enrollment. That's a huge bottleneck to [18:11] drug development and finding people who [18:13] are eligible and will benefit from being [18:15] involved in a particular trial. And if [18:17] you have that kind of of data, if people [18:19] are willing to sort of, you know, [18:21] entrust you with that information, that [18:23] that's something can actually really [18:24] benefit them and benefit the world at [18:26] the same time. And so what I view us as [18:28] building is really trying to build the [18:30] world's best healthcare platform to [18:32] really be able to bring health care into [18:34] the AI age. And I think that it's [18:36] something that is going to be absolutely [18:38] transformative to many people's quality [18:41] of life, really uplift so many people, [18:42] and we're seeing it already in such [18:44] concrete ways. Some of my favorite [18:46] stories about chatbt are people who say, [18:48] "Hey, information I got from chat helped [18:50] me save my own life. Help me save that [18:52] of a loved one that there was this [18:54] medical issue that someone had and that [18:56] I if you know the doctor told me one [18:58] thing, I was able to to double check [19:00] that and understand what they were [19:01] saying and be able to to push back on it [19:03] and got to a good outcome." And that [19:05] happens every single day. So I think [19:06] that health with these AIs is something [19:09] that it we're still just scratching the [19:10] surface of what's possible and I think [19:12] it's one of the most positive [19:13] applications of AI that that you can you [19:15] can think of. Yeah, I'm very interested [19:17] to see how uh the advancements in memory [19:20] intersect with health because I expect [19:22] that uh chatbt [19:26] with where memory has gone where I'll be [19:27] in a new thread and it will bring up [19:29] just the right information or tie back [19:32] to a thread that maybe happened three [19:34] weeks ago. When you actually apply that [19:36] to like health related queries, it may [19:39] be able to like pick up patterns that [19:42] sometimes would take a human years to [19:43] figure out like a certain ailment or [19:45] something like that where it's like, [19:46] hey, you're asking about all these [19:47] different things and maybe you thought [19:49] they were not connected. Turns out they [19:51] they actually are and you should go down [19:54] this sort of like rabbit hole. [19:56] >> Last question. I'm sorry. Please. [19:57] >> I was I was going to say I think that's [19:59] absolutely right. We're seeing that very [20:00] concretely and we've seen you know just [20:02] in my own personal life my my wife you [20:05] know talked about some of her her [20:06] medical conditions publicly but I it was [20:09] really this five-year journey of talking [20:10] to many specialists each one who was [20:12] kind of touching one part of the [20:13] elephant and would try to address that [20:14] one part and it was only finally her [20:16] allergist who said hey I think all these [20:18] symptoms you're seeing are connected and [20:20] you have this uh genetic condition that [20:22] affects all of your subsystems and [20:24] that's the kind of thing where it's [20:26] really hard to say how many people have [20:30] similar kinds of conditions and just [20:32] never find out. How many people have [20:33] these areas where it's like if you just [20:35] sort of are functionally specialized [20:38] that you're never going to bring [20:39] together the whole diagnosis and I think [20:41] that is one of the powers and potentials [20:43] of an AI that really deeply is able to [20:45] help you across all parts of your life [20:47] and also is a deep domain expert in all [20:50] areas of medicine. [20:51] >> Yeah. Uh I have one last question. Uh [20:54] what how do you tell the story of [20:55] operator? It feels like it was a failure [20:59] or a side quest, but it feels incredibly [21:02] important now given the advances in [21:04] computer use. Is there a clear lineage [21:06] there? What was operator? Does that [21:10] still exist somewhere within chat GPT? H [21:13] how does how did how did computer use [21:15] get solved? [21:17] >> Yeah. Well, look, I would look at all [21:18] these things as timing and all about [21:20] iterative deployment. Yeah. Right. that [21:22] that there's a moment where you need to [21:26] where the capabilities aren't quite [21:27] there but actually learning from real [21:30] world deployment is very helpful right [21:32] and the I think operator was just kind [21:33] of below threshold in terms of the model [21:35] capabilities it was a cloud-based system [21:38] that operated with computer use but it [21:39] was slow it wasn't fully accurate it was [21:42] like pretty painful to to use some [21:44] people got value but it really wasn't [21:45] above threshold and if you look at [21:47] what's happened that the team like one [21:49] thing openai does very well is we make [21:50] long-term investments on things that [21:52] really matter and we do the grind and [21:54] that the team this year I think really [21:56] started to build momentum that we put in [21:59] a lot of effort to go and sort of burn [22:00] down a long list of issues were able to [22:02] really focus on solving computer use and [22:05] I think that they delivered in a [22:06] significant way and there's more to do [22:09] never done all those things but it's a [22:11] true milestone I think people are really [22:12] appreciating what's possible because [22:14] we've been in a world with these agents [22:16] using computers through connectors right [22:19] through these very painstakingly coded [22:22] systems that are so different from how [22:23] humans use computers. Whereas humans can [22:26] already use everything on a computer, [22:28] right? Everything's designed for people. [22:30] So if you have an AI that can operate [22:31] that way and even from the very [22:33] beginning of OpenAI, we had a dream that [22:34] one day we could create such an AI, it [22:37] becomes able to help you across [22:39] everything that you would be able to do [22:41] with a computer yourself. And so I think [22:42] we're there with Astra. I think that [22:44] there's just so much more that people [22:47] are going to uncover in terms of [22:48] applications where this can go. But it's [22:50] an example of long-term focus, doing the [22:53] work, and not giving up even when the [22:55] going gets tough. [22:55] >> Yeah. And it feels like Astra, [22:58] my view is it really felt like all these [23:00] different bets coming together, you [23:01] know, at the right at the right time, [23:02] right? The the advancements in in the [23:04] model itself, the the computer use, [23:06] voice, all these things. Um, and it uh [23:09] it's all it's all making sense. So, [23:12] >> yeah. [23:12] >> Um, [23:13] >> together, it's focus. It's uh it's [23:15] something that I think this company does [23:17] extremely well when we really put a [23:19] challenge in front of us and think about [23:20] how to accomplish it safely well and uh [23:23] to to really deliver the value we're [23:24] doing thing. [23:25] >> Yeah. put different differently, it felt [23:27] like when you look at last year, it felt [23:29] like OpenAI was uh operating like a big [23:33] company and it and it was a big company [23:35] but but the way in which like product [23:37] experimentation was happening was you [23:39] know when you think of like a [23:40] hyperscaler they'll launch a new product [23:42] thinking okay if there's a 20% hit rate [23:45] or even a 10% or 5% chance that's okay [23:48] and then this year it feels like [23:49] actually the entire company switched [23:52] back into actual startup mode which is [23:54] like you know focus focus focus all [23:57] these things need to come together the [23:58] whole team needs to be rowing in the [24:00] same direction and then the difference [24:02] in momentum and growth and all these [24:04] things uh coming from that and and uh [24:07] actually taking the company from like [24:08] operating and shipping more like a big [24:10] company to shipping again and focusing [24:12] like a startup has been uh feels like an [24:15] impossible task and it's been uh [24:17] incredible to watch. So [24:19] >> yeah, [24:19] >> thank you. No, it's been a real real [24:21] effort from many many people at OpenAI [24:23] to really bring together and something [24:25] that that I really value that I think we [24:27] really value as a company and I think [24:28] that we're just so laser focused on our [24:30] mission and really thinking about every [24:32] piece of what we do should add up to [24:33] helping us accomplish it. [24:35] >> Well, thank you so much for taking the [24:36] time to come chat with us. [24:37] >> Great to see you. [24:38] >> We'll talk to you soon, Greg. [24:39] >> Thank you. [24:39] >> Talk the rest of your day. Goodbye.