Cuban Urges Pre-Signature AI Audits to Dismantle Insurer PBM Arbitrage

Why Mark Cuban Thinks AI’s Biggest Businesses Haven’t Been Built Yet — a16z

a16z

Mark Cuban argues that self-insured employers auditing contracts with artificial intelligence prior to signing would collapse legacy health insurer and pharmacy benefit manager business models by eliminating hidden pricing spreads.

AI-assisted summary of Why Mark Cuban Thinks AI’s Biggest Businesses Haven’t Been Built Yet — original source. Check the original for full context.

Source published:

Key ideas

  • Mark Cuban advocates that self-insured employers use frontier LLMs to audit benefits agreements prior to signing, using direct prompts like 'Where are they fucking me over?' to expose hidden pricing spreads and liability shields in carrier contracts. (18:51)
  • Cost Plus Drugs is scaling $20 million modular, automated manufacturing pods capable of rapid retooling for generic injectables and bespoke N-of-1 therapies, with early units ordered by federal agencies like FEMA and the military. (5:08)
  • Cuban proposes a structural overhaul to replace commercial insurance premiums with personal, interest-bearing escrow accounts backed by government-guaranteed bank advances and a catastrophic federal stop-loss safety net. (49:40)
  • Despite rapid advancements in clinical AI and near-zero drug design costs, human physicians will remain essential for hands-on sensory diagnosis, emotional care delivery, and interpreting algorithmic insights for patients. (39:23)

Detailed notes

## Background Published on YouTube by a16z on October 28, 2026, this episode features Mark Cuban in conversation with a16z General Partner Julie Yoo and Erik Torenberg. The discussion centers on Cuban's mission to make healthcare affordable through Cost Plus Drugs, the tactical application of AI to expose predatory benefits contracts, and the future of personalized medicine and transparent pricing.

## TL;DR Mark Cuban details how Cost Plus Drugs disrupts opaque healthcare conglomerates by using cost-plus transparent pricing, direct employer contracting, and automated modular manufacturing pods. He argues that while AI cannot fix a fundamentally abusive contract after it is signed, employers and consumers can aggressively prompt frontier models to audit complex payer agreements and uncover hidden spreads before committing capital. Cuban also outlines his broader vision for healthcare reform, including replacing conventional insurance premiums with interest-bearing escrow accounts, while anticipating an era where marginal drug design costs plunge toward zero and empower doctors rather than replace them.

## Atmosphere & style The conversation carries an energetic, plainspoken, and insurgent tone driven by Cuban’s characteristic directness and entrepreneurial impatience with corporate bureaucracy. Julie Yoo and Erik Torenberg provide a sharp venture capital and healthcare-insider framework, asking probing structural questions that channel Cuban's fiery critique of the major payers into practical mechanics. Listening feels like sitting in on an intense war-room strategy session, blending granular contract forensics with an optimistic, builder-centric vision for technological disruption.

## Bulletin - [18:51](https://www.youtube.com/watch?v=5UWDUD6qaM4&t=1131s) Mark Cuban advocates that self-insured employers use frontier LLMs to audit benefits agreements prior to signing, using direct prompts like 'Where are they fucking me over?' to expose hidden pricing spreads and liability shields in carrier contracts. - [05:08](https://www.youtube.com/watch?v=5UWDUD6qaM4&t=308s) Cost Plus Drugs is scaling $20 million modular, automated manufacturing pods capable of rapid retooling for generic injectables and bespoke N-of-1 therapies, with early units ordered by federal agencies like FEMA and the military. - [49:40](https://www.youtube.com/watch?v=5UWDUD6qaM4&t=2980s) Cuban proposes a structural overhaul to replace commercial insurance premiums with personal, interest-bearing escrow accounts backed by government-guaranteed bank advances and a catastrophic federal stop-loss safety net. - [39:23](https://www.youtube.com/watch?v=5UWDUD6qaM4&t=2363s) Despite rapid advancements in clinical AI and near-zero drug design costs, human physicians will remain essential for hands-on sensory diagnosis, emotional care delivery, and interpreting algorithmic insights for patients.

## Key takeaways - [00:00](https://www.youtube.com/watch?v=5UWDUD6qaM4&t=0s) Legacy health insurers and PBMs extract massive profits by funneling patients through captive subsidiaries and withholding raw EDI claims data from self-insured employers. - [03:13](https://www.youtube.com/watch?v=5UWDUD6qaM4&t=193s) Cost Plus Drugs combines open API pricing with a network of roughly 17,000 independent pharmacies receiving a flat $12 dispensing fee to eliminate refrigeration and shipping costs on cold-chain drugs. - [05:08](https://www.youtube.com/watch?v=5UWDUD6qaM4&t=308s) Automated mobile manufacturing pods priced at $20 million enable localized production of shortage-listed injectables and rapid development of personalized N-of-1 treatments. - [08:09](https://www.youtube.com/watch?v=5UWDUD6qaM4&t=489s) Direct contracting between self-insured employers and healthcare providers bypasses payer middlemen, eliminates prior authorization bureaucracy, and drastically reduces provider administrative overhead. - [09:18](https://www.youtube.com/watch?v=5UWDUD6qaM4&t=558s) Cost Plus Wellness publishes open-source direct contracting templates to help employers establish transparent, friction-free healthcare arrangements. - [14:10](https://www.youtube.com/watch?v=5UWDUD6qaM4&t=850s) AI cannot rescue employers from bad contracts once executed; algorithmic claims battles between payer and provider bots merely create an administrative standoff. - [18:51](https://www.youtube.com/watch?v=5UWDUD6qaM4&t=1131s) Automated public records pipelines using LLMs allow employers and municipalities to rapidly audit dense agreements and break the incumbent pricing model. - [22:49](https://www.youtube.com/watch?v=5UWDUD6qaM4&t=1369s) Regulatory costs like the roughly $365,000 FDA fee per Abbreviated New Drug Application represent a major capital barrier to expanding domestic generic drug manufacturing. - [25:52](https://www.youtube.com/watch?v=5UWDUD6qaM4&t=1552s) AI adoption in legacy healthcare conglomerates is primarily leveraged to widen corporate profit margins rather than lower consumer out-of-pocket expenses. - [30:25](https://www.youtube.com/watch?v=5UWDUD6qaM4&t=1825s) Frontier AI models lack real-time market intuition, requiring external scaffolding like agentfeeds.dev to ingest raw transcripts and commercial data for autonomous business agents. - [31:51](https://www.youtube.com/watch?v=5UWDUD6qaM4&t=1911s) Outside of clinical diagnostics, AI offers massive consumer leverage by helping patients navigate Explanation of Benefits statements and access non-profit hospital Financial Assistance Policies. - [35:54](https://www.youtube.com/watch?v=5UWDUD6qaM4&t=2154s) Advancements in AI drug design will cause the marginal cost of personalized medicine to approach zero, rendering trial-and-error mass-market generic pharmaceuticals obsolete. - [39:23](https://www.youtube.com/watch?v=5UWDUD6qaM4&t=2363s) AI will not replace doctors, but physicians must transition from rote memorization toward becoming 'physician scientists' and AI translators who manage personalized genomic care. - [46:01](https://www.youtube.com/watch?v=5UWDUD6qaM4&t=2761s) Epic dominates electronic health records, making direct point-of-care pricing integration the most effective avenue for pharmaceutical transparency. - [48:02](https://www.youtube.com/watch?v=5UWDUD6qaM4&t=2882s) Cuban outlines key federal healthcare reforms: unredacted public disclosure of all taxpayer-funded contracts, counting cash prescription payments toward deductibles, and opening non-profit hospital ledgers. - [52:30](https://www.youtube.com/watch?v=5UWDUD6qaM4&t=3150s) Frontier AI labs must shift from traditional white papers to data-driven, algorithmically targeted narratives across social feeds to counter public and regulatory backlash. - [56:48](https://www.youtube.com/watch?v=5UWDUD6qaM4&t=3408s) Enterprise markets will bifurcate cleanly into organizations that master AI and those that go out of business, making deep founder experimentation essential.

## Detailed walkthrough ### [00:00](https://www.youtube.com/watch?v=5UWDUD6qaM4&t=0s) Broken Economics and Incumbent Disruption

Healthcare fundamentally lacks competitive market dynamics. Mark Cuban notes that the market is severely inefficient and economically broken, while UnitedHealth operates over 3,000 subsidiaries and executes approximately $150 billion in intercompany transfers each year. These massive carriers raise premiums and deductibles while funneling patients directly into subsidiaries they secretly own. Cuban highlights the core objective of his venture: “The ultimate mission is to disrupt healthcare so that it's affordable again.”

Julie Yoo observes that while wealthy individuals often shy away from the confusing complexities of healthcare, Cuban boldly entered the space. His mere presence with Mark Cuban Cost Plus Drug Company has introduced competitive friction, forcing traditional incumbents to respond in ways that decades of government policy could never achieve.

Cuban notes that because Cost Plus Drugs publishes all of its prices openly through an accessible API, large corporations with "half a brain" pull that data daily to demand matching rates from their Pharmacy Benefit Managers (PBMs). This public pressure has caused legacy PBMs to use Cuban's brand as leverage during pricing disputes, with several major carriers even falsely claiming to corporate clients that Cost Plus Drugs is already part of their existing network:

> “Really, it truly does not surprise me when the big three or even the big six use our name as kind of a way to counter the request, in the discussion of pricing cuz they know that our prices are public, that anybody can take our API, and big companies that have half a brain are pulling that data on a daily basis and they're saying, 'You have to beat this price.'” — Mark Cuban

- UnitedHealth executes roughly $150 billion in internal intercompany transfers every year across more than 3,000 distinct corporate subsidiaries. - Incumbent health plans repeatedly increase patient deductibles and co-pays while directing members toward captive, carrier-owned services. - Major carriers frequently use Cost Plus Drugs' open pricing benchmarks to negotiate, even falsely claiming network affiliation without any formal contract in place.

---

[03:13](https://www.youtube.com/watch?v=5UWDUD6qaM4&t=193s) Expanding from 111 Medications to 4,000 SKUs

Cost Plus Drugs launched on January 19, 2022, with a lineup of just 111 generic medications. Cuban was unsure how the public would respond, but after he began promoting the company, consumer demand surged immediately. Rapid volume growth encouraged drug manufacturers to broaden their partnerships, scaling the online mail-order catalog to approximately 4,000 SKUs.

```mermaid flowchart TD accTitle: Cost Plus Drugs Core Offerings accDescr: The four distinct business segments of Cost Plus Drugs spanning mail-order, retail cards, custom manufacturing, and provider marketplaces.

subgraph DirectToConsumer["Direct-to-Consumer Channels"] A["costplusdrugs.com<br/>(4,000 Generic Mail-Order SKUs)"] B["TeamCubanCard.com<br/>(17,000 Affiliate Independent Pharmacies)"] end

subgraph B2BSupply["Manufacturing & Provider Marketplace"] C["Dallas Robotic Facility & Mobile Pods<br/>(FDA Short-Supply Drugs & N-of-1 Therapies)"] D["Cost Plus Marketplace<br/>(Cost + 10% to 12% to Clinics & Hospitals)"] end

A -.->|"Expands to Local Pickup"| B C -->|"Supplies Injectables"| D ```

To solve the mail-order limitation for patients needing immediate medication, the company launched TeamCubanCard.com—a local discount card accepted at 17,000 affiliate pharmacies. Cuban intentionally structured this model to protect independent community pharmacists by paying them a mandatory $12 dispensing fee per prescription.

While that $12 fee can make extremely cheap commodity drugs (such as a $5 statin) slightly more expensive than retail alternatives, the card unlocks dramatic savings on higher-cost specialty generics, biosimilars, and cold-chain items like insulin, sparing patients from paying high shipping and refrigeration fees.

- Launched online mail-order operations on January 19, 2022, scaling from an initial 111 generics to nearly 4,000 active SKUs. - TeamCubanCard.com partners with roughly 17,000 local independent pharmacies across the United States. - Affiliate retail pharmacies receive a flat $12 fill fee per order to ensure community operators remain financially solvent. - Cold-shipped biosimilars and insulin products yield substantial savings when collected locally via retail pickup compared to mail-order freight.

---

[05:08](https://www.youtube.com/watch?v=5UWDUD6qaM4&t=308s) Robotic Manufacturing, $20M Pods, and N-of-1 Therapies

Cost Plus Drugs began with a cold email from co-founder Dr. Alex Oshmyansky, who pitched Cuban on manufacturing generic injectables facing chronic shortages on the FDA drug shortage list—vital medications including pediatric cancer therapies, Pitocin, and epinephrine. Using robotics and AI, the team shrunk what traditionally required a football-field-sized plant into a compact 5,000-square-foot footprint in Dallas, Texas. The facility can run a six-month supply of an injectable drug and fully retool its production line in just four hours.

Taking that modular concept further, the company packaged the exact same automated setup into mobile shipping containers the size of tractor-trailers, called "pods." Priced at approximately $20 million each, these self-contained units can be shipped anywhere in the world and daisy-chained together to run clean rooms alongside generic tableting lines:

> “And these pods cost about $20 million. Ship it to a research hospital and if they're if they specialize in any types of therapies that you know for those people that are in the N of one category they can make it and iterate very quickly there.” — Mark Cuban

The federal government became their first customer, ordering initial pods for deployment by emergency agencies such as FEMA or the military during ecological or wartime disasters. The pods can also be placed directly at research institutions to develop hyper-personalized N-of-1 treatments, including antisense oligonucleotide (ASO) therapies formulated at the Dallas base.

To distribute these sterile injectables alongside inventory from partner manufacturers, Cuban launched Cost Plus Marketplace. The platform charges healthcare providers and clinics a simple Cost + 10% or Cost + 12% margin. Although the service saves facilities millions of dollars every year, Cuban notes their hardest hurdle is internal hospital bureaucracy: hospital CEOs are quick to sign off, but entrenched procurement staff often resist switching from their long-time vendor habits.

- Replaced football-field-sized production lines with a dense, 5,000-square-foot automated Dallas factory that turns lines every four hours. - Developed mobile tractor-trailer manufacturing pods priced at roughly $20 million each, with the U.S. government placing the initial orders. - Supports rapid-iteration N-of-1 specialized therapies and ASO drugs tailored for single-patient genetic profiles. - Cost Plus Marketplace delivers sterile injectables directly to health systems at Cost + 10% or Cost + 12%, bypassing institutional markups.

---

[08:09](https://www.youtube.com/watch?v=5UWDUD6qaM4&t=489s) Direct Employer Contracts to Eliminate Administrative Waste

Drawing from his own experience as a self-insured employer, Cuban engaged hospital CEOs and CFOs to understand their deep frustrations with vertically integrated health plans. Providers voiced intense anger over constant prior authorization delays, care denials, late reimbursements, retroactive clawbacks, and skyrocketing patient deductibles. Cuban observed that high-deductible plans effectively force health systems to act as subprime debt collectors, demanding out-of-pocket cash from patients before they can render care or tap their insurance benefits.

In response, Cuban began setting up direct contracts with hospitals, cutting out the carrier middlemen. His pitch balances operational simplicity with mutual accountability: he agrees to honor claims cleanly, on time, without prior authorization headaches, while taking direct financial responsibility for patient deductibles and out-of-pocket balances. In exchange, he asks health systems to deliver transparent, fair pricing and cut out administrative red tape. Cuban highlights his fundamental rule for these agreements: “Unless it's something crazy, trust the doctor. So, you're not going to need a pre-auth. There aren't going to be denials.”

- High-deductible insurance plans turn hospitals and clinics into de facto subprime debt collectors who must hunt down consumer balances before receiving reimbursements. - Direct employer-provider contracts cut out carrier middlemen by eliminating prior authorizations, bureaucratic coverage denials, and clawbacks. - Employers assume liability for contracted fees and patient out-of-pocket obligations upfront, provided clinical orders remain grounded and medically sound.

[09:18](https://www.youtube.com/watch?v=5UWDUD6qaM4&t=558s) Direct Contracting and Open-Sourcing Templates on Cost Plus Wellness

Mark Cuban explains the economic model behind direct contracting: in exchange for taking on the patient's credit risk so the provider is not forced to act like a “subprime lender,” he demands two concessions. First, he wants a significantly lower price, justified by the fact that administrative overhead, claims handling, and doctor time drop dramatically, raising the provider's net yield. Second, he insists on transparency.

Cuban requires the right to publish the signed direct agreement on Cost Plus Wellness (costpluswellness.com). The goal is to build an open-source clearinghouse of health contracts so that any employer can deploy them directly, any provider can list their terms, and even organizations that do not publish can use the documents as baseline negotiation templates against incumbents.

Julie Yoo connects this strategy to her recent thesis on the "great replacement cycle" of health plans. Employer-sponsored insurance remains the single largest insurance category in the United States, covering over 155 million people (more than half to roughly 60% of the entire population). Historically, this market was impenetrable for venture-backed startups because the legacy national carriers—the BUCAAs (Blue Cross Blue Shield, UnitedHealthcare, Cigna, Aetna)—held deeply entrenched broker relationships and proprietary provider networks with prohibitive upfront costs. However, startup employers are now reaching a breaking point as carriers impose aggressive, unsustainable price hikes.

- Over 155 million Americans rely on employer-sponsored benefits, representing the largest health insurance class in the country. - Carriers are currently pushing staggering rate hikes, with some startups experiencing premium increases of roughly 60% year-over-year.

[11:00](https://www.youtube.com/watch?v=5UWDUD6qaM4&t=660s) Vertical Integration, Hidden Spread Pricing, and Administrative Services Only (ASOs)

Cuban argues that the underlying cost crisis is far worse than most employers realize due to massive vertical integration across the major conglomerates. UnitedHealth Group alone operates over 3,000 subsidiaries and processes roughly $150 billion in internal, intercompany transfers each year—a financial volume that would rank them 14th in state GDP across the United States. Conglomerates like CVS Health and Cigna operate on comparable scales. These entities hike premiums, deductibles, and out-of-pocket costs while steering patients into wholly owned subsidiaries without clear disclosure.

The exploitation is particularly severe among self-insured employers, who represent roughly 60% of all Americans with company-sponsored coverage. While pharmacy benefit managers (PBMs) receive intense scrutiny for spread pricing, Cuban highlights that the medical claims processed by third-party administrators (TPAs) or carrier-owned Administrative Services Only (ASOs) represent an even larger financial drain.

```mermaid flowchart TD accTitle: Broken Flow of Medical Claims and Pricing in Self-Insured Health Plans accDescr: Diagram showing how ASOs hide pricing data between self-insured employers and hospitals through locked 835 and 837 files. subgraph Carriers["Vertically Integrated BUCAA Conglomerates"] direction TB ASO["Carrier-Owned ASO / TPA"] Subs["3,000+ Subsidiaries<br/>($150B Annual Intercompany Transfers)"] ASO --- Subs end

subgraph DataOpaque["Hidden Transaction Layer"] Files["Opaque 835 & 837 Electronic Claims Files<br/>(Reconciliation Blocked)"] end

Employer["Self-Insured Employer<br/>(PAYS HIDDEN SPREAD)"] Hospital["Hospital / Provider<br/>(RECEIVES DISCOUNTED REIMBURSEMENT)"]

Employer -->|"Pays unverified inflated bill"| ASO ASO -->|"Reimburses lower contracted rate"| Hospital Hospital -.->|"837 Claim Submission"| Files Files -.->|"835 Payment Data"| ASO Files x-.-x|"Data & claims access withheld"| Employer ```

Because medical care accounts for 90% of healthcare spending compared to pharmacy's 10%, the financial impact of unmonitored hospital spread pricing dwarfs drug markups: - Carriers negotiate opaque rates with hospitals, but the final bill the self-insured employer pays rarely matches the rate the hospital actually received. - Hospital machine-readable transparency files ("TiC" or Transparency in Coverage files) are frequently inaccurate or incomplete. - Carrier-owned ASOs deliberately lock down claims-level data, preventing employers from auditing EDI 835 (electronic remittance advice) and EDI 837 (electronic claim) transaction files. - Many self-insured employers are legally and practically blocked from accessing their own aggregate claims data. - Cuban calls the effort to disintermediate and remove these ASOs the true "holy grail" of modern healthcare reform.

[14:10](https://www.youtube.com/watch?v=5UWDUD6qaM4&t=850s) "Contractual Terrorism": Why AI Cannot Fix a Broken Contract

Addressing the surge of AI startups attempting to launch full-stack modern health plans, Cuban cautions that technology cannot outrun flawed market structures. While AI provides powerful tools for operations and clinical workflows, it cannot rescue an employer that has already signed an abusive contract in an opaque market without true price discovery.

Cuban labels the tactics used by large carriers through their ASO agreements as “contractual terrorism.” He reveals that when examining the City of Dallas's PBM agreement, the document ran 1,335 pages long—an administrative wall of text that no legal team can reliably vet without automated intervention. As a result, carriers easily insert terms that insulate themselves from liability and lock in arbitrary fee schedules.

> “There's no group of humans with enough coffee on the planet to be able to catch everything they try to squeeze by.” — Mark Cuban

Cuban argues that early-stage challengers like Sidecar Health do admirable work, but they face an uphill battle when trying to contract around legacy networks because entrenched carriers own sprawling webs of downstream subsidiaries designed to undermine transparent upstarts. This structural capture is why Cuban advocates directly for legislative intervention, specifically backing the "Break Up Big Medicine" initiatives to split insurer-owned clinical, administrative, and pharmacy entities into an open market.

[16:34](https://www.youtube.com/watch?v=5UWDUD6qaM4&t=994s) Claims Wars and the Architectural Disadvantage of Legacy Carriers

Julie Yoo observes that the current generative AI landscape is shining a harsh light on the perverse incentives of fee-for-service medicine, particularly through the escalating "bot wars" where provider bots battle payer bots over prior authorizations, denial management, and code reviews.

Cuban dismisses the algorithmic tug-of-war over claims submission, upcoding, and downcoding as mere peripheral noise:

> “The bot wars in terms of claims and up coding and down coding, that's short-term stuff, right? That that's just like, you know, okay, I need to lose some weight, I'm not going to eat, you know, my rice, I'm not going to eat my Frosted Flakes every day, right? It's nice on the periphery and it's good short-term play, but it doesn't really change everything because AI is a great equalizer.” — Mark Cuban

In Cuban’s view, claims bots will net out as both sides deploy offsetting frontier models from OpenAI, Anthropic, or proprietary enterprise systems. However, he identifies a massive architectural liability for legacy BUCAA payers: their corporate structures were assembled through decades of aggressive roll-ups and acquisitions. Managing more than 3,000 disparate subsidiaries leaves them burdened with deeply fragmented, siloed data systems that make it nearly impossible to transition into truly AI-native organizations.

Ultimately, Cuban stresses that AI's highest leverage point is not disputing a rejected bill after the fact, but auditing contracts upfront. He urges founders and business leaders to run every existing and prospective healthcare agreement through large language models before putting pen to paper.

[18:51](https://www.youtube.com/watch?v=5UWDUD6qaM4&t=1131s) "Where Are They Screwing Me Over?": Cuban's AI Prompt

Mark Cuban explains his exact playbook for dissecting complex healthcare agreements, whether they come from a broker, a consultant, a third-party administrator (TPA), or a pharmacy benefit manager (PBM). Rather than wading through dense legalese manually, Cuban feeds existing contracts into AI models with an aggressively direct instruction: “Where are they fucking me over? What should I do about it?” Within 30 seconds, the model highlights the hidden margin grabs, restrictions, and unfavorable terms line by line.

```mermaid flowchart TD accTitle: Cuban's AI Agent Pipeline accDescr: Automated workflow showing how AI agents find public healthcare records and analyze contracts to expose unfavorable terms.

subgraph Acquisition["Public Record Discovery"] A["AI Agents<br/>(Grok, Gemini, OpenAI)"] -->|"Search open records"| B["State Entities, Cities, Districts, Unions"] B -->|"Identify contracts & RFPs"| C["Draft Open Records Request Email"] C -->|"Cuban personalizes & sends"| D["Google Drive Repository"] end

subgraph Evaluation["Multi-LLM Contract Analysis"] D -->|"New contract ingested"| E["Multiple LLMs Run Analysis"] E -->|"Evaluate terms"| F["Single Prompt:<br/>'Where are they screwing me over?'"] F --> G["Good & Bad News Breakdown"] F --> H["Actionable Negotiation Steps"] F --> I["Simplified Explainer for Clients"] end ```

Cuban admits he is obsessed with autonomous AI agents and pays for various tiers across multiple providers. As an avid NBA fan, he jokes that he subscribed to Grok's plan because the price point reminded him of Luka Dončić's jersey number: "I got the Luka Dončić plan because it's $77.69 or something. I'm like, this is brilliant. Grok, $77, the Luka plan. I got you." He also runs Google Gemini and OpenAI subscriptions side by side. He sets his agents loose across public databases to locate every municipality, public school district, state agency, and union with public records access. The agents track down RFPs and contracts, automatically draft public records request emails, and drop them into his draft folder. Cuban adds a quick personal note, hits send, and deposits the acquired contracts onto a shared Google Drive monitored by all the models. Every time a new document appears, the models parse it and generate three outputs: the good news, the bad news, and an plain-English summary he can hand directly to school administrators or municipal leaders.

Through this system, Cuban reviews agreements brokered by the "Big Three" PBMs (CVS Caremark, Express Scripts, and Optum Rx) and the "BUCA" insurers (Blue Cross Blue Shield, UnitedHealthcare, Cigna, and Aetna) for Administrative Services Only (ASO) products. He routinely finds shocking markups imposed on public school systems, labor unions, and major cities like Denver, Dallas, and Fort Worth.

Cuban argues that self-insured employers—representing roughly 67% of covered employees and over 160 million Americans—wield enormous latent leverage. If they simply insisted on running their vendor contracts through an LLM before signing, the traditional model would crumble: > “The entire system for the big BUCAs and big PBMs and all their subsidiaries would collapse. The cost of healthcare in this country would drop like a rock.”

When corporate leaders and venture investors ask Cuban whether federal legislation is necessary to stop abusive healthcare costs, he pushes back. Employers do not need to wait for Washington; they need to appoint what he terms a dedicated "healthcare CEO or CFO" whose sole mandate is actively auditing, managing, and negotiating benefits agreements. He notes that several public companies followed his advice and uncovered massive overspending: "Oh my god, we had no idea how badly we were ripped off." However, those executives still refuse to call out the insurers publicly on quarterly earnings calls because they remain trapped in vendor relationships with the very same carriers. For any company with 1,500 or more covered lives, Cuban insists that running existing agreements through an AI model is the single fastest way to reclaim millions of dollars in waste.

---

[22:49](https://www.youtube.com/watch?v=5UWDUD6qaM4&t=1369s) The Grand Vision for Cost Plus Drugs: $20M Mobile Pods and Domestic Manufacturing

When asked about the long-term roadmap for Mark Cuban Cost Plus Drug Company, Cuban notes that while his ultimate political preference leans toward universal healthcare, universal coverage cannot function when underlying pricing data remains completely distorted. The true core offering of Cost Plus Drugs is not just cheap medications, but absolute trust. While a competitor could easily open an online storefront and undercut his pricing by advertising a "cost plus 1%" model, Cuban is confident that Cost Plus Drugs’ reputation shields it. The company spends zero dollars on paid advertising or traditional consumer marketing, relying entirely on word-of-mouth recommendations from customers who share their real savings. By strictly maintaining an uncompromised, transparent flat markup of 15%, the brand maintains credibility in an industry notoriously devoid of it.

Cuban's multi-billion-dollar scaling strategy relies on the modular manufacturing pods developed with his partners. These sterile, self-contained units carry substantial profit margins at a unit price of $20 million:

- **Near-term unit projections:** Cost Plus Drugs expects to sell several hundred manufacturing pods annually within two years. - **Five-year target:** The company aims to scale sales to a couple thousand units per year, potentially yielding $20 billion or more in annual pod sales. - **Onshoring economics:** Daisy-chaining modular pods together at their Dallas, Texas facility allows them to produce tableted generic medications at a lower unit cost than their contract manufacturing partners in India, without sacrificing quality.

The primary hurdle preventing immediate, widespread domestic production is regulatory filing friction rather than physical assembly. Submitting an Abbreviated New Drug Application (ANDA) to the FDA costs roughly $365,000 per generic drug, alongside additional regulatory surcharges: > “So you want to do a thousand of them, that's $365 million plus all the cost of the pods.”

Cost Plus Drugs is actively lobbying regulators to streamline this pathway so American drug manufacturing can be safely re-shored. Within two years, the company plans to place an American flag badge next to products on `costplusdrugs.com` indicating that the drug was synthesized and manufactured domestically inside their own pods. Joking about the massive potential valuation of a domestic manufacturing empire, Cuban adds with a grin: "Watch out, Elon."

---

[25:52](https://www.youtube.com/watch?v=5UWDUD6qaM4&t=1552s) Scale Capture and Why Technology Needs a Human Workforce

Addressing whether software alone can fix healthcare, Cuban explains that the market is hobbled by deep regulatory capture and "scale capture." When executive teams at vertically integrated healthcare conglomerates speak to Wall Street on earnings calls, they routinely discuss efficiency and technological upgrades. Yet their commentary reveals where those savings actually flow: > “They talk about technology, but the one thing they never say is this is going to translate into lower costs for employers and patients. They always say this is going to improve our earnings.”

Because legacy giants use technology solely to widen gross margins, buy back shares, and boost returns to their own shareholders, venture-backed startups cannot reform the system from within the standard carrier rails. Cost Plus Drugs refuses to deal with them directly, avoiding contract structures that trap outside innovators inside carrier-defined reimbursement games.

Julie Yoo asks what this technological evolution means for the healthcare talent pool and how younger workers should navigate career development over the coming five years. Cuban rejects the tech narrative that enterprises can simply automate away entry-level roles: 1. **The latency problem and foundational talent:** The moment an AI model is trained and deployed, its weights are fixed while the operational environment keeps evolving. Every model suffers from contextual latency. Organizations require humans-in-the-loop to evaluate context, handle novel edge cases, and witness ongoing operational hurdles firsthand so they can grow into institutional leaders. 2. **AI fluency over replacement:** Cuban emphasizes that automated tools will not eliminate human jobs broadly; instead, workers proficient with AI will displace those who refuse to adapt: > “AI doesn't replace jobs. People who know how to use AI replace the jobs of people who don't know how to use AI.” 3. **Executive education:** The real operational bottleneck rests inside the C-suite. Executive leadership teams urgently require training on foundational mechanics: grasping how autonomous agents function, how to deploy models, and distinguishing open-source models from proprietary ecosystems.

[28:31](https://www.youtube.com/watch?v=5UWDUD6qaM4&t=1711s) Why AI Is "Book Smart, Not Street Smart" and What C-Suites Miss

Mark Cuban emphasizes that corporate leaders must fundamentally understand the constraints and mechanics of AI before they can extract value from it. Closed models suffer from inherent latency; for example, the insightful conversation taking place on the podcast does not exist inside any frontier model until it is officially recorded, transcribed, and published on the open web. If founders or executives develop an idea in real time, current models are inherently behind it. Furthermore, large language models are primarily limited to text and static images, leaving them disconnected from the physical, video-based dynamics of the real world.

Cuban argues that AI lacks native business intuition and requires relentless human direction: “AI is not smart. It's, you know, it's book smart maybe, but it's not street smart. It's not, you know, entrepreneur smart.” Until C-suite leadership grasps this reality and starts actively experimenting, enterprise adoption will falter. To illustrate the gap in corporate awareness, Cuban recounts a meeting with the head of a major consumer packaged goods food company who was obsessing over potential brand acquisitions in response to consumer shifts driven by GLP-1 weight-loss medications:

> “I literally sat with the head of a consumer food company and he was talking to me about acquisitions and this was months ago and he was like, ‘Yeah, because of GLP-1s yada yada yada.’ And I'm like, ‘Okay, well, let's do this. Let's take your number one product, your cookie, right? And I'm going to ask ChatGPT to create a competitor that is more GLP-1 friendly and will be priced lower. And I want a full bill of materials. I want sources, everything manufacturing, what I have to do.’ And in about 3 minutes we got back to him and he was like, ‘Oh shit.’ He had no idea.”

Cuban contends that while anyone can prompt an LLM for direct tactical outputs, knowing how to structurally retool an entire organization around AI remains the primary bottleneck facing legacy enterprises today.

[30:25](https://www.youtube.com/watch?v=5UWDUD6qaM4&t=1825s) The Trillionaire in the Basement and the Agent-Driven Economy

Cuban proclaims that there has never been a better era in history to be an entrepreneur, predicting that autonomous agent architectures will produce the world’s first solo "trillionaire in the basement" through self-orchestrated agent swarms. However, major infrastructural bottlenecks still hamstring personal agents. Agents cannot natively scroll through or analyze social media feeds, scrape transcript data at massive scale, or parse commercial video advertisements. To bridge this information asymmetry in an emerging agent-driven economy, Cuban notes that the ecosystem must invent new ways to feed real-time commerce data directly into these systems.

To test this thesis, Cuban built an experiment called agentfeeds.dev. The platform allows users to drop in raw transcripts or content from feeds they follow, which can then be ingested by their personal AI agents—whether operating inside tools like Muse, dot, or Claude Co-work. By feeding agents structured ad data and niche domain updates, the agents stay continuously informed about product categories, consumer trends, and market dynamics. Despite ongoing questions around safety, alignment, and trust, Cuban believes that removing these distribution friction points will unleash an explosion of agentic commerce.

```mermaid flowchart TD accTitle: Agent Information Pipeline accDescr: Flow diagram showing unstructured social media content converted to structured transcripts and ingested by personal AI agents.

subgraph Ingestion["Content Capture"] A["Social Media Feeds & Ads"] -->|"Extract transcripts"| B["agentfeeds.dev Platform"] end

subgraph Processing["Context Delivery"] B -->|"Structured data ingestion"| C["Agent Platforms\n(Muse / Dot / Claude Co-work)"] end

subgraph Execution["Autonomous Action"] C --> D["Autonomous Commercial Decisions"] C --> E["Consumer Price Optimization"] end ```

[31:51](https://www.youtube.com/watch?v=5UWDUD6qaM4&t=1911s) How Patients Can Use AI to Hack Non-Profit Hospital Assistance

Shifting to healthcare, Cuban asserts that outside of clinical diagnostics, AI’s greatest leverage point will be in the hands of patients and ordinary consumers navigating opaque billing mechanics, such as the Explanation of Benefits (EOB). With approximately 40% of Americans unable to afford a surprise $400 emergency medical expense, widespread terror governs family healthcare decisions. Cuban advises individuals to proactively prompt AI models to map out financial safety nets before a medical catastrophe strikes.

Under federal regulations, every non-profit hospital is legally required to operate a Financial Assistance Policy (FAP). While these programs reference the Federal Poverty Level (FPL), qualification thresholds often scale up to 600% of the FPL—encompassing households earning over $100,000 depending on the state and family size. Cuban suggests that instead of paying exorbitant insurance premiums, some consumers could evaluate running their numbers through an AI model, determining their hospital assistance eligibility, and redirecting those premium dollars into high-yield money market accounts.

- Non-profit hospitals must maintain structured financial assistance programs, yet fail at outreach: “When I talk to the heads of hospitals, I'm like, ‘You don't understand. You guys suck at marketing. You are dependent on the BUCA’s [Blues, United, Cigna, Aetna] and their plans and being part of their network to feed you patients.’” - Cuban envisions a startup model that integrates automated agents directly into hospital financial relief portals, allowing middle-class families to query eligibility instantly rather than getting trapped in collections. - Just as office workers resisted personal computers before Lotus 1-2-3 normalized the $500 software spreadsheet, consumer apprehension toward AI will evaporate once individuals see it protect their personal bank accounts from medical debt.

[35:54](https://www.youtube.com/watch?v=5UWDUD6qaM4&t=2154s) Personalized Medicine and the Collapse of Drug Design Costs

Host Erik Torenberg references Aaron Swartz’s famous aphorism that “information wants to be free,” contrasting it with healthcare's fortress of proprietary, siloed datasets, and asks Cuban how frontier AI research labs will reshape the industry. Cuban responds by predicting a total collapse in the marginal cost of molecular drug design:

> “The cost of designing a drug personalized to you after reviewing your DNA and knowing everything that it knows will start approaching zero as the capabilities of models go up.”

While the tech sector remains fixated on GPU compute scaling, optical networking, and massive power generation, Cuban argues that rapid algorithm efficiency is the real catalyst. Within a horizon of 5 to 20 years, generic mass-market medicine will look completely obsolete. Today, individuals enter a retail pharmacy and pick up standardized off-the-shelf over-the-counter medications like Advil, Tylenol, or ibuprofen under the false assumption that identical compounds affect every human body the same way.

Cuban notes that this trial-and-error approach will give way to hyper-personalized compounds tailored to each person's genetic markers and metabolic data. This shift will start in over-the-counter remedies and quickly expand into critical prescription categories—such as blood thinners, where patients are arbitrarily forced to choose between Eliquis, Xarelto, or Warfarin. Cuban reveals that he has directly challenged leaders at two frontier AI labs to deploy their models toward bespoke personal drug synthesis rather than basic text processing.

[038:15] Personalized Medicine and Manufacturing On-Demand Drugs

```mermaid flowchart LR accTitle: The On-Demand Personalized Medicine Pipeline accDescr: A flow diagram showing how genetic inputs move through AI inference and into on-demand mobile drug pods. subgraph Inputs ["Patient Inputs"] DNA["Patient DNA / Profile\n($99 or Low Cost)"] end subgraph Compute ["AI & Modeling"] Infer["Inference & Analysis\n(Rapidly falling marginal cost)"] Nof1["N-of-1 Drug Formulation\n(Tailored to unique biology)"] end subgraph Production ["Care Delivery"] Pods["Mobile Manufacturing Pods\n(Local, real-time drug production)"] Patient["Patient Delivery\n(Included in standard subscription)"] end

DNA --> Infer Infer --> Nof1 Nof1 --> Pods Pods --> Patient ```

Mark Cuban lays out how the economics of personalized medicine will radically shift as marginal costs plunge. While inference and computational power to handle medical requests are currently expensive, those costs are dropping at an extraordinary rate. Cuban predicts that bespoke "N-of-1" medicine—tailored specifically to an individual's unique biology, brain, and bodily variables—will eventually be bundled into an everyday consumer subscription of $20 or $200 a month. Drawing an analogy to genetic testing, he points out that consumers already pay $99 or less to have companies like 23andMe sequence their DNA. If a patient is comfortable storing that genetic data, algorithms can continuously analyze it in the background. Whether or not someone actively wants to know their latent genetic risks in advance, the infrastructure will be in place so that the moment something goes wrong, systems can immediately identify the ideal compound.

When that capability matures, the bottleneck shifts from digital discovery to physical creation. Cuban argues that Cost Plus Drugs is uniquely positioned to dominate the physical layer through its modular manufacturing facilities. He notes that the vision is to have their localized, mobile manufacturing pods ready to formulate and produce these individualized medications on demand: “We want our pods to be right there to be able to manufacture them because we're the only ones capable of doing it.”

Julie Yoo points out that true personalized medicine represents an enormous disruption to existing care delivery models. Today, an immense amount of a doctor's everyday workload consists of basic medication management—troubleshooting why a mass-market drug is causing bad side effects, titrating dosages, or advising patients on lifestyle adjustments just to help them tolerate a pill. If pharmaceuticals become better, individualized products from the start, that administrative and clinical burden could be fundamentally altered.

[039:23] Why AI Cannot Replace the Human Doctor

Cuban firmly rejects the notion that artificial intelligence will make human physicians obsolete, emphasizing that physical medicine cannot operate with digital latency or detached automation. Using a vivid hypothetical, Cuban explains that if he takes a newly formulated personalized drug and suddenly starts violently vomiting in a hospital, he does not want a screen or an automated machine checking in: “You can have it on video, right? Then you can have a robot there say, 'How do you feel, Mark?' Right? And the Terminator might might walk in and say, 'Your time is up.' I don't know. But but I'd rather have a human there with all five senses being able to take a look and ask questions and see the crying mom or the crying son or child or whatever and be able to include that in the context.” He emphasizes that technology adoption in high-stakes clinical settings will always require an experienced professional who understands which clinical variables actually matter.

Instead of eliminating doctors, technological evolution will reshape medical school curricula. Doctors will no longer be trained purely to memorize rote facts; rather, they must learn to utilize advanced clinical search tools like OpenEvidence to interrogate complex models, interpret genomic data, and translate those technical findings into empathetic, actionable advice for patients. This human translation layer becomes even more vital because individuals will essentially require personalized models tailored to their unique biology.

Cuban also highlights an looming crisis that AI entrepreneurs often overlook: intellectual property rights. While the tech industry frequently operates on the premise that "information wants to be free," healthcare creators and patent holders view their intellectual property very differently: - **Circumventing traditional patents:** With modern AI tools, individuals can take an existing medical patent, tweak variables slightly, and claim a competing version. - **Paywalled clinical intelligence:** In response to IP vulnerability, inventors and institutions will increasingly lock proprietary procedures and clinical discoveries behind steep paywalls, charging high inference fees (e.g., $9,999 per access) or mandating proprietary software rather than open-sourcing their findings. - **Data availability bottlenecks:** The critical debate in medical AI is not just about building cheaper frontends that route queries to the lowest-cost model; it centers on how to access the protected, highly specialized IP required to train, post-train, or run Retrieval-Augmented Generation (RAG) on those models when IP holders refuse to share it freely.

[043:28] The Physician as Scientist and the Need for Human Translators

Julie Yoo agrees with Cuban's assessment, countering the prevailing fear of AI-driven physician displacement by arguing that the medical profession will actually need to expand: “I agree that actually I think we're going to need more doctors in the future because as care advice becomes more abundant, more people are going to demand healthcare, actual like real life healthcare services.” Yoo observes that much of current clinical practice has been degraded into bureaucratic, paint-by-numbers routines governed by administrative quality measures where doctors barely use their deep medical intellect. As AI automates routine tasks, physicians can elevate their role to that of "physician scientists." Instead of executing rote tasks, doctors can operate at the frontier of clinical discovery—collecting novel, individualized data from patients and interpreting how unique biologies respond to novel interventions.

Cuban wholeheartedly agrees with this framing, stressing that “novel data equals person.” While regular individuals will benefit from longitudinal monitoring—such as continuous blood pressure tracking via next-generation wearables rather than the absurd standard of an annual cuff check at a clinic visit—the flood of novel physiological data will require expert human mediation. As Cuban gestures toward his own wearable device to show he already tracks his health metrics constantly, he explains that society will need human "AI translators." These professionals will bridge the gap between ordinary people who simply want to live their lives and the algorithmic engines that process their data, ensuring that an individual's unique physical state is correctly understood by AI models and that the models' complex outputs are clearly and safely communicated back to the patient.

[046:01] Incumbent EHRs and Epic's Market Position

Yoo turns the conversation toward electronic health record (EHR) vendors, noting that Cuban rarely comments on this deeply entrenched layer of healthcare incumbents. When asked how EHR systems might evolve or be disrupted in the era of artificial intelligence, Cuban admits he respects the unyielding dominance of the incumbent market leader: “Honestly, I don't know. You know, the EHR is dominated by Epic and it's their world, you know, and so I've just kind of deferred to them and tried to stick where I can have an impact because, you know, we partner with them.”

Cuban explains that Cost Plus Drugs focuses on strategic integration with Epic to display real-time pharmaceutical pricing directly at the point of prescribing, empowering physicians and patients to view affordable drug options together in the clinic room. Referring to recent industry announcements involving Epic and retail giants like Amazon, Cuban praises the general movement toward surfacing upfront medication costs directly inside clinical workflows. However, he voices frustration with the sluggish deployment pace typical of healthcare IT rollouts, venting his annoyance that a high-impact point-of-care pricing announcement was scheduled with a massive implementation delay, failing to go live until May of the following year.

[47:02](https://www.youtube.com/watch?v=5UWDUD6qaM4&t=2822s) Healthcare Spending, GDP, and Productivity

The conversation opens with an exchange on whether healthcare will inevitably remain an overwhelming burden on the United States economy. The host asks whether, in ten years, healthcare will still consume a fifth or a sixth of US gross domestic product, questioning if there is a kind of terminal state where demand continually outstrips supply, capping the sector at roughly 20% of the entire economy regardless of general GDP growth. Mark Cuban agrees that the spending level will likely stay that high, but he argues the core nature of that spend will undergo a fundamental shift.

Rather than pouring funds into what Cuban characterizes as mere "sick care"—the traditional, reactive treatment of acute illness—the investment will shift toward keeping individuals genuinely healthy. This preventative posture yields substantial economic dividends: people become markedly more productive, lose fewer workdays to illness, and experience enhanced cognitive clarity and learning capacity. While the raw share of GDP devoted to healthcare may remain static, Cuban maintains that the societal output and human value extracted from that spend will drastically increase, more than compensating for the top-line cost in ways today's healthcare infrastructure fails to deliver.

[48:02](https://www.youtube.com/watch?v=5UWDUD6qaM4&t=2882s) Cuban's Four-Point Plan to Disrupt the Healthcare Status Quo

Prompted by a hypothetical scenario where he advises the next president of the United States on how to solve the country's healthcare crisis, Cuban lays out the exact policies he regularly recommends when testifying before state legislatures. His strategy is built around breaking the informational asymmetry that inflates prices and protects entrenched corporate middlemen:

```mermaid flowchart TD accTitle: Cuban Healthcare Reform Framework accDescr: A flow illustrating Cuban's four policy pillars to reform healthcare transparency and overhaul the insurance model.

subgraph Transparency["Information Transparency"] A["1. Unredacted Public Contracts<br/>(Mandatory for all entities taking taxpayer funds)"] B["2. Cash-Pay Deductible Credit<br/>(Cheaper out-of-pocket finds apply to deductibles)"] C["3. Open Non-Profit Ledgers<br/>(Detailed general ledgers & procurement receipts published)"] end

subgraph Restructuring["Systemic Restructuring"] D["4. Replace Insurance with Escrowed Accounts<br/>(Deposits pegged to ACA Silver benchmarks)"] E["Bank-Loan Liquidity & Government Guarantees<br/>(Payroll deductions pay back medical borrowing)"] F["Federal Stop-Loss Threshold<br/>(Catastrophic backstop kicked in above e.g. $40k)"] end

Transparency -->|"Restores Market Discovery"| Restructuring D --> E E --> F ```

- **Make all public-dollar contracts fully transparent:** Every single vendor, provider, or administrator receiving taxpayer money must publish their contracts in full without redactions. Cuban emphasizes that the moment contract terms are dragged into daylight, true price discovery occurs, creating an efficient market that forces prices down: “One, make all contracts with anybody who takes taxpayer money public. No redactions. because the minute that happens, you start to have an efficient market and the costs go down.” - **Credit out-of-network savings toward deductibles:** Patients who shop around and locate lower-cost prescription drugs or medical procedures on the open market should be legally permitted to apply those cash outlays directly toward their insurance deductible, a reform already adopted to some degree across eight states. - **Mandate detailed general ledgers for non-profit hospitals:** Any non-profit health system claiming tax exemptions must publish its entire granular general ledger, down to every single line-item accounting entry, supplier invoice, and procurement requirement. Because these entities operate under public subsidies, Cuban insists taxpayers have an absolute right to inspect every transaction. - **Eliminate insurance carrier arbitrage:** Cuban points out that 72% of large health insurer revenue originates from taxpayer funding, yet these corporations assume virtually no genuine underwriting risk: “They don't take risk anymore. They offload it. Everything's an arbitrage for them.”

[49:40](https://www.youtube.com/watch?v=5UWDUD6qaM4&t=2980s) Escrow Accounts and Government-Backed Stop-Loss Overhaul

Cuban delivers an indictment of the commercial health insurance model, emphasizing the unending financial drain it imposes on American families: “Think about that. whether it's Medicare, unless you're on Medicaid, right? You are paying till the day you expire and when you need it, you have to fight for it in the current system and probably foreseeable systems.” To replace this dynamic, he outlines an alternative consumer-directed healthcare financing structure.

Under his framework, families would stop sending premiums to insurers and instead divert those exact amounts into dedicated personal escrow accounts held at financial institutions, pegged to the cost of an ACA Silver benchmark plan (for example, roughly $2,100 a month for a family of five in Texas, scaled to income). The individual retains complete legal ownership of these deposited funds and any interest that accrues. If an unexpected medical episode occurs that exceeds the accumulated balance, a coordinated structure takes over:

1. **Partnered Bank Loans:** The bank automatically advances the necessary capital to settle provider invoices. 2. **Government Loan Guarantees & Payroll Deductions:** The state or federal government guarantees the medical loan, ensuring providers are paid immediately without fear of uncompensated care, while repayment is recovered gradually via routine payroll deductions. 3. **Federal Stop-Loss Backstop:** A portion of consumer deposits funds an overarching stop-loss pool that absorbs catastrophic costs surpassing a predefined ceiling (such as $40,000). 4. **Retirement Rollover:** If a consumer maintains good health and accumulates unspent balances over their career, the entire balance plus compound interest belongs to them when they transition to Medicare at age 65.

Cuban argues it is absurd that the federal government routinely underwrites home purchases, SBA business loans, and student debt, yet leaves individuals entirely exposed to financial ruin during unforeseen medical emergencies. By combining dedicated personal savings accounts with bank loans and government-backed stop-loss programs, he asserts: “Now, all of a sudden, bye-bye insurance companies. Now all of a sudden you're not fighting back because it's your money to spend as you choose.”

[52:30](https://www.youtube.com/watch?v=5UWDUD6qaM4&t=3150s) Advice to AI Labs: Beating Social Media Algorithms at Their Own Game

When the hosts shift the discussion to the AI sector, asking how frontier companies like OpenAI and Anthropic should address their widespread public relations challenges and consumer backlash over issues like data center expansion, Cuban does not mince words: “I've had these conversations right with them and I told them they're idiots, you know, because what controls how every pretty much everybody in this country thinks right now? Social media algorithms.”

Cuban illustrates this digital atomization by describing a recent conversation about local voting patterns with a 23-year-old colleague. The coworker reported that peers of the same age living in Texas had no idea who high-profile state leaders like Ken Paxton or James Talarico were. The anecdote reveals a reality where the public no longer consumes shared information across common newspapers, magazines, or evening broadcasts. Instead, platforms like TikTok isolate users in hyper-tailored information silos driven entirely by algorithmic engagement. Cuban notes that inspecting his 17-year-old son’s social media feed exposes a hyper-personalized loop of basketball, luxury cars, girls, and an occasional political post, proving that each user lives in an entirely distinct media universe.

Cuban argues that publishing dry academic white papers and running conventional television advertisements during sporting events is completely obsolete for shifting public sentiment. If frontier AI companies genuinely possess superior machine intelligence, they should use that technology to reverse-engineer social media feeds, segment populations precisely, and run dynamic digital messaging campaigns directly inside user feeds: “Do it like the Russians do it. It doesn't matter, right? Because that's what's at stake for you.” He views the public opposition surrounding massive data centers not as a distinct technological debate, but simply as a proxy for the public's fundamental misunderstanding of artificial intelligence—a vacuum of knowledge left unfilled because model developers fail to communicate within modern algorithmically curated channels.

[56:48](https://www.youtube.com/watch?v=5UWDUD6qaM4&t=3408s) The Blank Canvas of AI and Cuban's Advice to Founders

Julie Yoo asks Mark Cuban about whitespace opportunities in the market. Noting that AI has suddenly made previously intractable problems addressable, she asks if there is a specific industry or market segment where he looks around and wonders why nobody is building there yet.

Cuban's answer is immediate and sweeping: "all of them." Whenever he talks to young people, he shares a core thesis about how the corporate and entrepreneurial landscape is splitting in two. Cuban puts it bluntly: “Those who are great at AI and those who have gone out of business.” He extends that same binary division to individuals: “Those who use AI to learn anything and those who use AI so they don't have to learn anything.” In his view, the individuals who harness artificial intelligence as an aggressive engine to expand their knowledge—rather than using it as a shortcut to bypass critical thinking—will be the ones who discover which industries and business models are failing to leverage modern tools.

```mermaid flowchart TD accTitle: Mark Cuban's AI Dichotomy for Companies and Individuals accDescr: Diagram illustrating Cuban's two types of companies and two types of users regarding AI adoption.

subgraph Companies["Company Outcomes"] C1["Great at AI"] C2["Out of Business"] end

subgraph Individuals["User Mindsets"] I1["Uses AI to Learn Anything<br/>(Discovers Whitespace & Disruption)"] I2["Uses AI to Avoid Learning<br/>(Replaced & Irrelevant)"] end

I1 -->|"Drives"| C1 I2 -->|"Leads to"| C2 ```

Cuban stresses that this mindset applies across generations, whether speaking to teenagers or to 50-, 60-, and 70-year-old entrepreneurs. The biggest barrier facing founders right now is simple discomfort with conversational AI. People are still hesitant to talk directly to models via voice or chat. He draws a historical parallel to the arrival of early digital spreadsheets: workers initially refused to trust the software and insisted on double-checking digital figures with their 10-key adding machines. While users still need to audit outputs to catch hallucinations and errors, the real unlock comes from orchestrating different frontier models against each other. When analyzing opaque contracts, Cuban routinely feeds the output of Grok into ChatGPT, prompting the second model with: "Hey, one of your peers came out and said this about this contract, what do you think?" Spending a few hours cross-examining models reveals angles and vulnerabilities that human reviewers would take days to spot.

- **The scale of the technological transition:** Having lived through personal computing, the rise of the commercial internet, and mobile, Cuban considers this the single most profound platform shift: “This is the greatest transitional technology we have ever seen and I'm on I've been around for all of them, right? And this blows them all away.” - **Regional advantages and global potential:** Silicon Valley and Bay Area youth have an early cultural edge because they watch their parents, mentors, and peers experiment fearlessly. However, once founders across the rest of the United States and the world develop that same confidence, an entirely new wave of unimagined businesses will emerge. Cuban compares that upcoming breakthrough moment to the earliest days of social networks like Friendster, where the paradigm was so unfamiliar that people struggled to classify it. - **Aggressive, unconventional experimentation:** Cuban urges builders not to hold back from testing scenarios that look ridiculous on the surface: “Don't be shy about using AI in things that feel really uncomfortable and weird because that uncomfortableness is probably the path to something that is groundbreaking and gamechanging.” He describes running experiments where he holds two phones side-by-side, prompting two AI models by voice and letting them converse directly with one another while he sits back and listens to their debate.

Julie and Erik thank Cuban for joining the show, and Cuban wraps up the discussion, noting how much fun he had breaking down healthcare, market incentives, and the future of technology.

## Notable quotes > [25:52](https://www.youtube.com/watch?v=5UWDUD6qaM4&t=1552s) AI doesn't replace jobs. People who know how to use AI replace the jobs of people who don't know how to use AI. — Mark Cuban

> [43:28](https://www.youtube.com/watch?v=5UWDUD6qaM4&t=2608s) I think we're going to need more doctors in the future because as care advice becomes more abundant, more people are going to demand healthcare, actual like real life healthcare services. — Julie Yoo

> [35:54](https://www.youtube.com/watch?v=5UWDUD6qaM4&t=2154s) The cost of designing a drug personalized to you after reviewing your DNA and knowing everything that it knows will start approaching zero as the capabilities of models go up. — Mark Cuban

> [28:31](https://www.youtube.com/watch?v=5UWDUD6qaM4&t=1711s) AI is not smart. It's, you know, it's book smart maybe, but it's not street smart. It's not, you know, entrepreneur smart. — Mark Cuban

> [56:48](https://www.youtube.com/watch?v=5UWDUD6qaM4&t=3408s) Don't be shy about using AI in things that feel really uncomfortable and weird because that uncomfortableness is probably the path to something that is groundbreaking and gamechanging. — Mark Cuban

## Mentioned Mark Cuban, Julie Yoo, Erik Torenberg, Dr. Alex Oshmyansky, Luka Dončić, Elon Musk, Aaron Swartz, Ken Paxton, James Talarico, UnitedHealth Group, Mark Cuban Cost Plus Drug Company, Cost Plus Drugs, TeamCubanCard.com, Cost Plus Marketplace, Cost Plus Wellness, Blue Cross Blue Shield, Cigna, Aetna, CVS Health, CVS Caremark, Express Scripts, Optum Rx, Sidecar Health, Epic, OpenAI, Anthropic, Grok, Google Gemini, ChatGPT, TikTok, Friendster, Lotus 1-2-3, OpenEvidence, 23andMe, agentfeeds.dev, Muse, dot, Claude Co-work, FDA, FEMA, Affordable Care Act (ACA), Medicare, Medicaid, Small Business Administration (SBA), Eliquis, Xarelto, Warfarin, Advil, Tylenol

## Video description Mark Cuban thinks AI could transform healthcare, but it won’t fix opaque prices and broken incentives on its own. His starting point for employers: run every benefits contract through AI and ask where you’re getting ripped off.

Mark joins a16z General Partner Julie Yoo and Erik Torenberg to discuss what he’s learned building Cost Plus Drugs, why trust is its core product, and how greater transparency could put pressure on healthcare costs.

They also explore where AI can help, what personalized medicine could look like, how the role of doctors may change, and why Mark believes founders should use AI to learn, not as an excuse to stop thinking.

Timestamps: 0:00 Intro 0:50 Cost Plus Drugs: 111 Meds to 4,000 SKUs 6:25 $20M Mobile Factories That Make Any Drug 9:00 Direct Contracts That Bypass the Middlemen 11:30 How UnitedHealth Really Makes Money 15:25 Why AI Can't Save You After You Sign 19:45 "Where Are They Screwing Me Over?": Cuban's AI Prompt 25:50 Why Tech Alone Won't Fix Healthcare 31:40 The Biggest AI Win Is for Patients 35:30 The End of One-Size-Fits-All Drugs 39:23 Why Doctors Won't Be Replaced 47:36 If Mark Advised the President 53:06 His Advice to the AI Industry

Resources: Follow Mark Cuban on X: https://x.com/mcuban Follow Julie Yoo: https://x.com/julesyoo Mark Cuban Cost Plus Drug Company: https://costplusdrugs.com/ Cost Plus Wellness: https://costpluswellness.com/

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Find a16z on X: https://twitter.com/a16z

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Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see http://a16z.com/disclosures.

[Source](https://www.youtube.com/watch?v=5UWDUD6qaM4)

中文简报

库班呼吁签署前借助AI审计以破除医保PBM套利 马克·库班指出,自保雇主在签约前使用人工智能审计合同,将通过消除隐性价差,瓦解传统健康险公司和药品福利管理公司的商业模式。 马克·库班详细阐述了Cost Plus Drugs如何通过成本加成的透明定价、与雇主直接签约以及自动化模块化制造舱,来打破不透明的医疗巨头格局。他认为,虽然AI在签约后无法挽救一份根本上存在霸王条款的合同,但雇主和消费者可以在投入资金之前,积极向最前沿的模型输入提示词来审计复杂的付款方协议,并揭露隐藏的价差。库班还概述了他对医疗改革更广泛的构想,包括用带息托管账户取代传统保险费,同时他预见边际药物设计成本将大幅趋近于零,从而赋能医生而非取代他们。 马克·库班主张自保雇主在签署福利协议之前使用前沿大型语言模型进行审计,利用直白的提示词(如“他们到底在哪里坑了我?”)来揭露承运商合同中隐藏的定价差价和免责条款。 (18:51) Cost Plus Drugs正在扩大价值2000万美元的自动化模块化制造舱规模,这些制造舱能够针对仿制注射剂和定制的N对1疗法快速完成换线改装,首批设备已被联邦紧急事务管理局(FEMA)和军方等联邦机构订购。 (5:08) 库班提议进行结构性改革,用由政府担保的银行垫款和联邦灾难性止损安全网支持的个人带息托管账户,来取代商业保险保费。 (49:40) 尽管临床AI正在迅速发展且药物设计成本趋近于零,但人类医生在亲身感官诊断、提供情感关怀以及为患者解读算法见解方面依然不可或缺。 (39:23)

Source quotes

[25:52] Mark Cuban: AI doesn't replace jobs. People who know how to use AI replace the jobs of people who don't know how to use AI. [43:28] Julie Yoo: I think we're going to need more doctors in the future because as care advice becomes more abundant, more people are going to demand healthcare, actual like real life healthcare services. [35:54] Mark Cuban: The cost of designing a drug personalized to you after reviewing your DNA and knowing everything that it knows will start approaching zero as the capabilities of models go up. [28:31] Mark Cuban: AI is not smart. It's, you know, it's book smart maybe, but it's not street smart. It's not, you know, entrepreneur smart. [56:48] Mark Cuban: Don't be shy about using AI in things that feel really uncomfortable and weird because that uncomfortableness is probably the path to something that is groundbreaking and gamechanging.

Original transcript

[0:00] We are not in an efficient healthcare [0:02] market. The economics are broken. [0:04] >> One of the many ills of healthcare is [0:05] that it completely lacks competitive [0:07] dynamics. Just merely by the presence of [0:10] plus drugs, you've actually forced [0:11] change in the incumbents. [0:13] >> United Health 3,000 plus subsidiaries, [0:16] $150 billion in intercomp transfers [0:19] annually. There's often times when they [0:21] will increase premiums, increase [0:23] deductibles, and at the same time force [0:25] you into a relationship with a company [0:28] they already own and you don't know they [0:29] own them. The ultimate mission is to [0:32] disrupt healthcare so that it's [0:34] affordable again. [0:34] >> Is there like some area where you're [0:36] like, why is no one building here? [0:38] >> There's no better time to be an [0:40] entrepreneur than right now. The biggest [0:42] challenge and where AI, I think, is [0:44] going to have the biggest impact is [0:49] Well, Mark, welcome to the podcast. [0:51] Thanks so much for joining. [0:52] >> Thanks for having me on, guys. [0:54] >> Julie, what has struck you about Mark's [0:56] contributions in in the space? What what [0:58] have you always found fascinating about [1:00] about what Mark's been up to with Cos [1:02] Drugs or and just in general, and why [1:04] you invited him on to the show? I mean [1:06] Mark uh first of all just had the [1:08] courage to enter into the morass that is [1:11] healthcare in a way that made such a [1:12] splash and that many many people who you [1:15] know also are in the privileged position [1:17] that Mark is in to just have such a huge [1:19] audience have um been intimidated you [1:21] know to do over over many many decades [1:23] and so um I've loved watching uh the [1:26] market react to what Mark has done in [1:28] healthcare. I think you know the one [1:30] thing I know Mark you and I have talked [1:32] about this in the past but um healthcare [1:33] is like one of the industries like one [1:35] of the many ills of healthcare is that [1:36] it completely lacks competitive dynamics [1:38] and competitive forces free market [1:40] dynamics all that kind of stuff and [1:42] what's been fascinating to watch is just [1:44] merely by the presence of cost plus [1:47] drugs as one one example and we'll talk [1:48] about others that you've done to but um [1:50] just merely by that by by the presence [1:52] of that of that entity and what you what [1:54] you represent and what you're doing [1:55] you've actually forced uh change in the [1:58] incumbents that otherwise like even with [2:00] policy, even with like all sorts of [2:03] other forces like never never changed [2:04] over the course of many many decades. So [2:06] that's that's one of Yeah, cuz I don't [2:09] get to see that stuff cuz I don't talk [2:10] to those guys. [2:12] >> And then I think to your point like even [2:13] absent a contract, I think people are [2:15] recognizing from the demand side of the [2:17] market that they need to show that there [2:19] is some pathway for people to get your [2:21] product, right? And so perhaps even in [2:23] the absence of a direct contract, um you [2:25] know, I do I do hear people talking [2:28] about you know, your solution as part of [2:30] their network. [2:31] >> Really, it truly does not surprise me [2:32] when the big three or even the big six [2:34] use our name as kind of a way to um [2:37] counter the request, you know, you know, [2:40] in the discussion of pricing cuz they [2:42] know that our prices are public, that [2:44] anybody can take our API, and big [2:47] companies that have half a brain are [2:48] pulling that data on a daily basis and [2:51] they're saying, "You have to beat this [2:52] price." And so I I can see that. But, [2:55] you know, I've had at least one company [2:57] and probably more um that have said, [3:01] "Oh, yeah, it's, you know, pick one of [3:03] the big three has told us that you're [3:05] part of their network and we get your [3:07] prices where you're cheaper, and we [3:09] don't have an agreement at all with any [3:11] of the big three." [3:13] >> Mark, let's zoom out and take stock [3:15] about where where you're at with the [3:16] business. You you you launched in 2022 [3:20] uh with a few dozen drugs. In April this [3:22] year, you said you were up to roughly [3:23] 4,000. Uh you're getting into [3:25] manufacturing, hospital contracts, [3:27] potentially AI based care. Why don't you [3:29] take stock a little bit of where the [3:30] business? [3:31] >> I'll give you the rundown. So, we [3:32] launched costblooddrugs.com June 19th, I [3:35] mean January 19th of 2022. 111 [3:37] medications, purely generic, and you [3:40] know, we didn't know what to expect at [3:42] all. I went out and started talking [3:43] about it and it immediately blew up, [3:45] right? And then you know our volumes [3:47] there led the manufacturers to expand [3:50] their portfolio with us and we were able [3:52] to add additional manufacturers. So now [3:55] as you said we have you know 4,000 SKs [3:57] give or take and our business every week [3:59] is up and to the right. So our biggest [4:00] challenge is just keeping up with it. So [4:02] that's segment number one. Then the [4:04] obvious response to mail order is well I [4:07] need to pick things up today. And so we [4:09] created what's called the [4:10] teamcubancard.com. [4:12] I did not name it. And it's basically a [4:15] discount card that allows you to go to [4:17] any of the 17,000armacies that have [4:19] affiliated with us and pick up any of [4:22] our not any of but most of our drugs [4:23] locally because we pay I'm a big [4:26] believer in supporting independent [4:27] pharmacy. So, we pay our affiliate [4:30] umarmacies [4:32] $12 um fill fee, which means that's [4:35] going to make us more expensive for the [4:37] lowest cost drugs because if you have a [4:39] $5 statin plus $12, you're going to get [4:41] it cheaper somewhere else. But at the [4:43] same side, if you really want to support [4:45] your independentarmacies, you can pick [4:47] up the cheap drugs. But on the more [4:49] expensive drugs, the specialty generics, [4:51] the bioimilars were actually much [4:53] cheaper. And for things like bioimilars [4:55] and insulin and things that have cold [4:57] shipping, it's actually cheaper to buy [4:59] it and pick it up locally through our [5:01] team Cuban carb. So that's the second um [5:03] stool in in what we offer. Third is cost [5:06] plus marketplace. Well, before I get to [5:08] cost plus marketplace, let me go back to [5:10] our Dallas manufacturing. So a big part [5:13] of um Alex, my co-founder, Dr. Oxmanski, [5:18] his original cold email to me was he [5:20] wanted to manufacture drugs that were [5:22] generic drugs that are on the FDA short [5:24] supply list because there are pediatric [5:26] cancer drugs. There are things that are [5:28] widely used in hospitals. penov um [5:31] ptocin, epinephrine, this long list of [5:33] drugs and we were able to use AI and to [5:37] use um robotics to shrink what would [5:39] have been a football field or more into [5:42] 5,000 square ft. And um not only that, [5:46] but we were able to turn drugs every [5:49] four hours. So we can make a six-mon [5:51] supply, turn the line, and then go to [5:54] the next drug and continue doing and we [5:56] sell those products to hospitals and [5:57] clinics. an extension of that because [6:00] we've been doing that for you, we [6:02] started working on that five years ago. [6:04] Um, we've been able to take those same [6:06] robotics and AI and shrink it into a [6:10] manufacturing plant, if you will, the [6:12] size of a tractor trailer. And we call [6:14] those pods. And those pods can be used [6:17] for anything and shipped anywhere. The [6:19] government was our first customer. Um, [6:21] we've shipped the first one here [6:22] recently where we just got an order for [6:24] a second and they told us there's more [6:26] behind that because if there's an [6:28] ecological disaster, we can send it to [6:30] FEMA if the if FEMA's around. If there [6:32] is um weather disaster, military [6:35] disaster, god forbid, we can ship them [6:37] there and configure them to make any [6:39] specific type of drug. So we can [6:41] configure a pod for um sterile [6:43] injectables for you know multiple pods [6:46] can be daisy chained together so we can [6:48] scale and or you can have one as being a [6:50] sterile room and another doing the the [6:53] the tablet work for generics and I'm not [6:56] the expert on this. Alex can go into [6:57] this in precise detail, but the thing [7:00] I'm most proud of, and actually Stat [7:02] News just wrote a story on this [7:03] yesterday, the day before, is that we [7:05] can take these pods and configure them [7:08] to do um N of one therapies so that we [7:11] can ship the pod to a research hospital. [7:14] And these these pods cost about $20 [7:15] million. ship it to a research hospital [7:18] and if they're if they specialize in any [7:20] types of therapies that you know for [7:22] those people that are in the N of one [7:24] category they can make it and iterate [7:26] very quickly there and then now we're [7:29] doing these ASO drugs and don't ask me [7:30] what ASO stands for because I can't [7:32] pronounce it um out of our um first [7:35] manufacturing facility in Dallas. So [7:37] that's part two. From that [7:39] manufacturing, we created cost [7:41] plusmarketplace.com. [7:43] Um, sorry, cost plus marketplace. And [7:45] cost plus marketplace takes those [7:47] sterile injectables we make and that we [7:49] also others that we source from other [7:51] providers or other manufacturers and we [7:53] sell them at a cost plus 10 or cost plus [7:55] 12 to clinics, hospitals, providers, [7:57] whoever want to buy them at the cheapest [7:59] price. And we literally can save [8:01] hospitals millions of dollars a year. Um [8:04] but our biggest challenge there is we [8:06] convince the CEOs but we can't always [8:07] convince the purchasing people to do it. [8:09] Um and then finally um because of my own [8:13] experiences as a self-insured employer [8:15] and going around and talking to hospital [8:17] CEOs and CFOs and learning their [8:19] relationship with the big carriers, the [8:22] big vertically integrated carriers and [8:23] all the things they like and dislike [8:25] mostly dislike. I went to them and said, [8:27] "Look, I know you hate um the delays, [8:30] the denies, the preos, the, you know, [8:33] the late pays, the clawbacks, the fact [8:35] that, you know, the your plans are or [8:38] the carrier plans keep on increasing [8:40] deductibles, turning the uh providers [8:42] into subprime lenders because they have [8:44] to collect the deductibles before they [8:46] can offer the care or before they can [8:48] get access to the insurance money. [8:50] Knowing all these things, I'd like to [8:52] work out a direct contract, but I want [8:54] two things. I'm going to tell you what [8:55] I'm going to give you in exchange for [8:56] those two things. One, I'm going to [8:58] trust the doctor. Unless it's something [9:00] crazy, trust the doctor. So, you're not [9:02] going to need a pre-auth. There aren't [9:04] going to be denials. Now, we had [9:05] somebody who had Munchhousen's disease [9:07] that required a denial. But, you know, [9:09] other than that, if it's something [9:10] crazy, I'm going to pay the price that [9:12] we contract for on time. I'm going to [9:15] take responsibility for the patient out [9:16] of pocket. Either I'll pay it or I'll [9:18] I'll take the credit risk for the [9:20] patient itself. So you don't you're not [9:22] a subprime lender, you know, and in [9:24] exchange for all that, I want two [9:27] things. I want a better price because [9:28] your associated administration and [9:30] overhead and doctor time is much less. [9:33] Your yield's going to be higher. And I [9:35] want the ability to take the contract we [9:37] signed, this direct contract between us, [9:38] and publish it on cost [9:40] pluswwellness.com. [9:41] So it can act as an open source for all [9:44] of these contracts so that any employer [9:47] can use them and any provider can post [9:49] their contract and even if you don't [9:51] want to post or use, you can use them as [9:53] templates in your own negotiations. [9:55] >> Well, I love the last piece, Mark, [9:56] because I think that was the genesis of [9:57] our thread back and forth when I [9:59] published a piece a few weeks ago on [10:01] what I'm calling like the great [10:02] replacement cycle of of health plans and [10:04] for I mean for so long so you know [10:06] employer sponsored health benefits is [10:08] the largest class of insurance in our [10:10] country. um if you think about it that [10:11] way. So, you know, roughly about I think [10:13] 155 million Americans are covered by an [10:15] employer sponsored benefit or more. [10:17] >> Yeah, more. But in any case, it's more [10:20] than half the country, 60% of the [10:21] country. And um historically, it's been [10:24] completely, you know, monopolized by the [10:26] buas like these national carriers. And [10:29] um and it's been an unadressable market [10:31] from a startup perspective, right? Like [10:33] it's the the relationships were super [10:35] entrenched. You needed these national [10:37] networks to, you know, be able to play [10:38] in the game. And so the like starting [10:40] cost to sort of enter the arena was was [10:42] too high for startups to get into and [10:44] and the relationships were just too [10:45] entrenched. Now uh the premium uh [10:48] increases are just freaking ridiculous, [10:50] right? Like this year we're seeing even [10:52] amongst our startups um some Buas are [10:55] forcing like 60% year-over-year [10:57] increases in premiums. And it's just [11:00] >> it's even worse than you think, Julie. [11:02] You know, not not to step in, but [11:05] >> because they're vertically integrated. [11:06] So, United Health 3,000 plus [11:09] subsidiaries, [11:10] $150 billion in intercomp transfers [11:14] annually. That would make them number 14 [11:16] in GDP in the United States among [11:18] states. [11:19] >> And so, that tells you how big they are. [11:21] And CVS Sigma are not far behind. And so [11:25] there's often times when they will [11:27] increase premiums, increase deductibles, [11:29] increase um out-of-pocket costs, and at [11:32] the same time redirect you or actually [11:34] force you into a relationship with a [11:37] company they already own and you don't [11:39] know they own them. And you talk about, [11:41] you know, employer based insurance, [11:42] particularly those who self-insure. 60% [11:45] of people who get their health care from [11:47] companies get it from self-insured [11:48] employers. And those employers need [11:51] someone to process all the medical [11:53] claims. put aside pharmacy, the medical [11:55] claims, those things are called [11:56] thirdparty administrators. And if [11:58] they're owned by the big buas, they're [12:00] called ASOS, administrative services [12:02] only. And those administrators, you [12:04] know, we hear all the time about the [12:06] problems with PBMs and how they spread [12:08] price. Well, on the medical side, it's a [12:10] million times worse because [12:13] >> it's also chunk of market. [12:15] >> What's that? [12:15] >> It's also the bigger chunk of the market [12:17] relative to [12:18] >> of course. Yeah, it the medical side is [12:19] much bigger. you know, 10% in growing [12:21] versus the other 90%. And what they do [12:24] is the plans and the hospitals have [12:28] their own contracts. And the hospitals, [12:30] unless they're market dominant, have the [12:33] hate the buas and those contracts, but [12:35] more importantly, whatever that [12:37] relationship is, the self-insured [12:39] employer has no idea what the terms of [12:42] that relationship is. Right? Even though [12:45] it's possible you can go on the hospital [12:47] and look up the tick file, you know, the [12:49] transparency files for that relationship [12:51] and that plan, they're not always [12:53] correct. They're not always right. But [12:55] what ends up happening is the price that [12:58] your the employer pays, the self-insured [13:00] employer pays rarely matches the amount [13:03] that was charged or the amount that was [13:06] paid to the hospital. So there's a [13:08] spread pricing there. And to make [13:09] matters worse, those ASOs that are owned [13:12] by the BUAS make it impossible to [13:15] reconcile the numbers so that you can [13:17] see if you're paying more or less. And [13:20] they do things, you know, there's these [13:21] things called 835 and 837 files, which [13:24] is the data that's sent to the hospital [13:26] and the amount of money that's paid in [13:28] response to those claims. And the [13:30] employers have no access to it. And in [13:32] many cases, they don't even have access [13:33] to their own claims. It is just so [13:36] rigged to your point Julie trying to you [13:39] know remove them and disintermediate [13:42] them is the key the holy grail to what's [13:46] happening in healthcare right now. [13:48] >> Yeah. And we're I mean we're super [13:49] excited to see just an influx of um [13:51] startups that are now able to go after [13:53] this market. A big reason why in [13:55] addition to all these market forces and [13:56] again like the economics just getting to [13:58] a breaking point is the fact that AI can [14:00] play a significant role in enabling a [14:03] full stack like health plan offering to [14:05] be built in a way that reduces all the [14:08] craft that you're describing in a very [14:09] short period of time. [14:10] >> But this all comes down to who takes the [14:11] risk. [14:13] >> While AI I'm a huge AI fan. Live it, [14:15] love it. I think it's important on the [14:17] clinical side. I think it's important on [14:19] the operational side. I think it's most [14:21] important short term on the contractual [14:23] side. But the reality is in a broken [14:26] financial system, even when you [14:27] introduce AI into the economics and the [14:30] operations and the processes, when it's [14:33] already broken, you can't fix it because [14:36] you you brought up the point right at [14:37] the beginning, Julian, you're 100% [14:39] right. We are not in an efficient health [14:42] care market. The economics are broken. [14:45] And you see that [14:48] because if you don't have price [14:50] discovery, that's one thing that [14:52] protects you, that keeps you from having [14:54] an efficient market. But what's even [14:56] worse, and here's where the market, the [14:58] economics really start to fall apart. [15:00] And what makes it tough for AI in the [15:02] short term operationally and and less so [15:05] clinically, [15:06] the contracts are so big and so long, [15:10] the buas through their ASOS get to be [15:12] contractual terrorists. [15:15] And what I mean by contractual [15:16] terrorism, the city of Dallas on their [15:18] PBM contract, I haven't been able to see [15:21] their ASO contract yet, 1335 pages. Mhm. [15:26] >> There's no group of humans with enough [15:28] coffee on the planet to be able to catch [15:30] everything they try to squeeze by. [15:32] >> And so, as a result, no matter what AI, [15:35] once you sign a contract, now hopefully [15:37] you use AI to prevent yourself from [15:39] signing a bad contract. And I think [15:40] that's the lowhanging fruit for [15:42] everybody, but once you sign that [15:44] contract with terms you don't fully [15:45] understand and conditions you don't [15:48] fully you can't even protect yourself [15:49] against, they win. There's no AI in the [15:53] planet that can protect you. And when [15:55] you try to compete with them on plans, [15:58] right, that sounds good and I'm all for [16:00] it, right? What sidecar is doing and so [16:02] many others are doing is really smart, [16:04] but they're having problems because, [16:07] you know, yes, the wraparound networks [16:09] are needed and yes, putting together a [16:10] network is hard. But those buas have so [16:14] many subsidiaries, [16:16] they [ __ ] with you somewhere and you [16:17] don't even realize it. And that's the [16:20] ultimate challenge. And that's why I'm [16:22] so big on the break up big medicine bill [16:24] and going after these companies because [16:26] I want I want this to be an open market [16:29] for every entrepreneur, you know, to use [16:32] AI in every way possible. [16:34] >> And so you you were you you went exactly [16:36] where I was going to go, Mark, which is [16:37] one of the areas where AI is playing a [16:39] role for better for worse is that it is [16:41] is just shining a light on how broken [16:43] the underlying system that humans [16:44] designed is right. So the whole like [16:45] prior bot war situation that's happening [16:48] right now between payers and providers [16:49] is one of you know people blame the AI [16:52] but it's actually no it's like AI is [16:53] just implementing the existing fee for [16:55] service billing system to the full [16:57] extent and showing us how broken that [16:58] system is. So I'm curious to like what [17:00] your take is on what's the end state of [17:02] that like clearly your direct [17:03] contracting uh methodology it sounds [17:05] like is able to reduce a lot of the [17:08] information asymmetry and contract [17:10] clarity and and things of that sort. Is [17:12] that what it's going to take or [17:13] >> so the bot wars in terms of claims and [17:16] up coding and down coding that's [17:18] short-term stuff right that that's just [17:20] like you know okay I need to lose some [17:23] weight I'm not going to eat you know my [17:26] rice I'm not going to eat my frosted [17:28] flakes every day right it's nice on the [17:32] periphery and it's good short-term play [17:35] but it doesn't really change everything [17:36] because AI is a great equalizer [17:40] your AI my AI [17:42] you're open, you know, open AI, [17:43] myanthropic, whatever it is, we're going [17:46] to battle each other out and you might [17:48] win a couple innings, I'll win a couple [17:49] innings, but they're they're going to [17:50] net out at some level. So, I don't see [17:53] dramatic change in the long term. Maybe [17:56] if you're first in, you can pick up some [17:58] things and you see some um lawsuits and [18:00] you see some challenges um when one side [18:03] has it and the other side doesn't, but [18:06] the revenue cycle management on the [18:08] hospital side is is pretty darn good. [18:10] And the Buas have an have a big problem [18:14] in my opinion because they grew through [18:17] acquisitions. We mentioned these 3,000 [18:19] subsidiaries. That's a lot of siloed [18:21] data. And even though you can try to [18:23] find ways to get access to claims and [18:26] specific things that allow you to upcode [18:27] and they're doing that, it's going to be [18:29] hard for them to be become AI native [18:32] companies on the BUA side. And I think [18:34] over the long term they're going to be [18:36] challenged. But all of this starts, and [18:39] I can't say this enough, all of this [18:41] starts before you before those employers [18:44] sign their contracts. If every one of [18:46] your portfolio companies said, "You know [18:49] what? I'm going to run my existing [18:51] benefits contract. If I have a broker, [18:53] if I have a consultant, if I have um a [18:55] TPA, if I have a PBM contract, I'm [18:59] running my existing contract through AI [19:01] and I'm asking and I'm using a prompt [19:03] that asks a single question. Where are [19:05] they [ __ ] me over? what should I do [19:07] about it? And within 30 seconds, you're [19:09] going to see bam, bam, bam, bam, bam, [19:11] bam, bam, bam, bam. And the things I've [19:12] seen running through contracts because [19:14] let me just tell you how much I love AI [19:16] agents. So, I use them all. I use [19:18] Grockbot. I use Eric and I are NBA fans. [19:21] And so, I got the Luca um Donix plant [19:24] because it's $77.69 [19:26] or something. I'm like, this is [19:28] brilliant. Crockpot, $77, the Luca plan. [19:30] I got you. And then I have the Gemini [19:33] plan. And then I have OpenAI's plan, [19:35] etc. etc. And I use the agents and [19:37] instinct too and dot and I use the [19:40] agents and I say you go out and find me [19:43] every state entity organization [19:46] enterprise that um has an open records [19:49] opportunity and I want you to find me [19:52] every single contract RFP whatever it is [19:55] you can find um from those entities and [19:58] I want you to write the letter to [20:00] request it. Put it in an email. Put it [20:02] in my draft. Let me personalize it some. [20:04] tell me when it's there and I'll hit [20:06] send. And it's amazing, right? Stuff [20:09] that's always been at the bottom of the [20:10] list that I always wanted to get to but [20:12] never could. Now it's just like this [20:14] stuff is coming. And so I put it up on [20:16] Google Drive and each of the the [20:18] different um LLMs has access to it. And [20:22] I just tell them all every time there's [20:23] a new um something new loads on the [20:26] drive, you go through and you tell me, [20:28] you give me the good news, you give me [20:30] the bad news, you give me what should be [20:32] done, and then you give me the simple [20:33] version so I can send to the company or, [20:35] you know, school or whatever it is. And [20:37] bam, bam, bam, bam, bam. And that's [20:39] where I get to see all these contracts [20:42] that the big three on the PBM side and [20:44] the BUAS on the ASO side are signing. [20:47] And so I get to see specifically how all [20:50] these enterprises are getting ripped off [20:52] these school districts. Oh my god, [20:55] cities from Denver to Dallas to Fort [20:58] Worth unions. I mean, and if you think [21:02] about it, again, going back to your [21:04] perfect point, Julie, is if that 67%, if [21:08] the employers representing 67%, the 160 [21:13] million plus Americans actually did one [21:16] thing, one thing, ran their contracts [21:20] through AI before they signed them and [21:23] negotiated from that, the entire system [21:27] for the big buas and big PBMs and all [21:30] their subsidiaries would collapse. The [21:32] cost of health care in this country [21:34] would drop like a rock. And so when I go [21:36] and I talk to employers, when I go talk [21:39] to investors and talk about their [21:41] portfolio companies and they're like, [21:43] "Do we need legislation? Do we need this [21:45] that?" I'm like, "No, you need to be [21:48] smart and do your job and bring in [21:51] somebody that I call a healthcare CEO or [21:53] CFO whose only job is to manage the [21:56] contracts and everything associated with [21:58] it." And you will find that your health [22:01] care costs will go down. And then once [22:04] we get you there, then we can talk about [22:06] carving out for direct contracts and [22:07] doing all these other things [22:10] immediately. Like there's a couple um [22:13] public companies that I told to do this [22:15] and came back to me and were like, "Oh [22:17] my god, we had no idea how badly we were [22:19] ripped uh ripped off and I'm begging [22:21] them to mention it on their quarterly [22:22] earnings conference calls and they won't [22:24] do it because they still have to do [22:26] business with those buas even though if [22:27] they left them for whatever reason." [22:29] Yeah. And so if we just do that one [22:31] thing, run the contract soup. Literally, [22:34] if you have more than 1,500 employees, [22:37] the quickest way for or members I should [22:39] say, the quickest way for that startup, [22:41] that tech company, maybe depending on [22:44] how bad you're ripped off, into the [22:45] millions or more, is to just do what I [22:47] just said, run your contracts through [22:48] AI. [22:49] >> Yeah. Mo Mark, maybe maybe zooming out, [22:51] c can you share more about sort of the [22:53] the grand vision for for the business a [22:55] few years out and maybe how you think [22:57] about sequencing to to get there? [23:00] >> So, a couple things. One, I mean, the [23:02] ultimate mission is to disrupt health [23:05] care so that it's affordable again. And [23:08] I'm a fan of universal health care, but [23:09] you can't get to universal health care [23:11] until you have correct data and people [23:14] can make decisions based off of real [23:16] data. So, that's bigger system. whatever [23:20] direction it ends up going, I just want [23:21] to disrupt healthcare so that when [23:23] people think about the economics, it [23:25] becomes okay, I know exactly what's [23:27] going on, how we get there, more [23:30] education than anything else. Like I [23:31] mentioned before in terms of the [23:33] business of cost plus drugs. Look, [23:35] somebody could come along for the retail [23:37] site and say, "We're going to do cost [23:38] plus 1%." Okay, trust is still our [23:42] primary product. That's what I try. We [23:44] don't spend any money on marketing or [23:45] advertising. And when we first got [23:47] started, all the people who came from [23:48] farming said, "Oh, you're going to get [23:49] killed." I'm like, "No, you know, people [23:51] are going to tell others how much money [23:52] they saved." And then they're going to [23:54] trust us. And that's the one thing [23:55] missing in all of healthcare economics, [23:57] trust. And so once we gain their trust [24:00] by doing exactly what we said by being [24:02] fully transparent, only having a set [24:04] markup of 15% will garner people trust. [24:07] So that'll protect us elite to some [24:08] level. But the Grand Dio's vision, those [24:10] pods I told you about that sell for $20 [24:13] million, [24:15] there's good margin in those. And we [24:17] think we can sell within two years, a [24:20] couple hundred a year, within five [24:23] years, a couple thousand a year. So you [24:25] give me, you know, a thousand um pods to [24:28] sell at $20 million each, we're going to [24:31] be doing really, really, really good. [24:34] And it'll completely change healthcare [24:36] because we can daisy chain those things. [24:38] Like literally, we could manufacture [24:41] tableted generic drugs in Dallas, Texas [24:44] using these and make them for less than [24:47] we pay India, the manufacturers we [24:50] partner with in India. Now, we don't go [24:51] for the cheapest price. We go for the [24:53] best manufacturer. So, we pay a little [24:55] bit more. But still, we can make it for [24:57] less. The only thing holding us back is [25:00] that for each generic we have to fill [25:02] out we have to um apply for something [25:04] called another new drug application. And [25:07] each one of those things cost $365,000 [25:10] plus other fees. So you want to do a [25:12] thousand of them that's $365 million [25:14] plus all the cost of the pods. We're [25:16] trying to say look if we truly want to [25:19] um bring manufacturing and onshore for [25:21] medications we're here for it and we can [25:23] do it. you're already working with us in [25:25] other areas and so we think we'll get [25:28] there as a big part of what we'll do and [25:30] we've already planned so that on cost [25:32] plusddrugs.com we'll put a little bit of [25:34] little American flag when something is [25:37] manufactured by us here in the US but [25:39] that's probably two years away just [25:41] because of all the work we have to do [25:42] with the FDA but that's the big picture [25:45] if we're if we're selling $20 billion [25:47] worth of pods a year [25:50] watch out Elon [25:52] >> and and so is your view that as If you [25:53] look out the next few years, no matter [25:55] how good the technology gets, it's not [25:58] going to sort of disrupt uh sort of [26:00] healthcare on its own and that there [26:01] needs to be other more structural [26:03] changes that need to happen. [26:04] >> Yeah. Yeah. There's regulatory capture [26:06] and there's scale capture. Right now on [26:08] the economic side, it's all scale [26:10] capture. And when you listen to the [26:12] cordians conference calls or read the [26:14] transcripts for all those big vertically [26:16] integrated companies, they talk about [26:18] technology, but the one thing they never [26:20] say is this is going to translate into [26:22] lower costs for employers and patients. [26:26] They always say this is going to improve [26:28] our earnings. You know, we're going to [26:30] return more to shareholders. We're going [26:32] to buy back stock. [26:35] But until I'm able to educate all these [26:37] employers, right, they're going to keep [26:39] on making it nearly impossible. Which is [26:42] why, you know, when Julie talked about [26:43] earlier about CVS, why I mentioned we [26:46] don't deal with any of them directly [26:49] because we have to work outside of them [26:51] because otherwise you fall into their [26:52] trap and they gave me with their [26:54] contracts. [26:56] Mark, what do you um in all this, you [26:58] know, you're talking a lot about uh [27:00] structural things, but there is a [27:01] reality of what you described earlier [27:03] like AI will change the nature of [27:04] people's jobs in this industry quite a [27:06] bit. What do you think is I I've heard [27:07] you talk a lot about, you know, how do [27:09] we sort of futureproof our, you know, [27:11] young pools of talent and you know, what [27:13] is um being like sort of career ready [27:15] look like in this day and age? What do [27:17] you think that looks like for [27:18] healthcare? Like what does the the [27:20] workforce of healthcare look like in the [27:21] next 5 years? [27:22] >> I mean, it looks the same as any other [27:24] industry. you have to still hire [27:26] entry-level people [27:28] >> because no matter what the the model is [27:31] the minute it's released that's it right [27:34] it's it's behind it's behind and so [27:36] there's latency associated with every [27:38] model and so you need people who can who [27:41] are aware of everything that's going on [27:42] that create context and deal with the [27:44] models be the human in the loop [27:46] understand the consequences etc and you [27:48] need those people to grow with the [27:49] organization over time so that all as [27:52] all these things changed they've seen [27:54] the history of the implementation and [27:56] they can bring value to the [27:57] organization. So that's part one. You [27:59] can't just get rid of all entry- level [28:01] positions. Part two, you have to enable [28:04] those people and everybody else white [28:06] collar oriented how to use AI because AI [28:09] doesn't replace jobs. People who know [28:12] how to use AI replace the jobs of people [28:14] who don't know how to use AI. So that's [28:16] part two. And then part three is the [28:18] bigger picture stuff. The first step to [28:21] that is trying to educate the seauite on [28:23] how AI even works. Teaching them how [28:26] agents work. Teaching them how to use a [28:27] model. Teaching them, you know, the [28:30] difference between open- source and [28:31] closed models and the things you [28:33] different things you have to do. Helping [28:35] them understand the latency of a model [28:37] that this brilliant conversation the [28:38] three of us is having are having is in [28:41] no model anywhere and won't be until [28:43] it's published. So, if we say something [28:45] that we can all go out and use, the [28:47] models are all behind and AI is all [28:49] behind. So that's a given and of course [28:51] you know LLMs are text and some pictures [28:54] and don't deal with you know all the you [28:56] know real world things that are going on [28:58] in video. So you have to be able to [29:00] understand as a CEO and in the seauite [29:02] how all those things impact your [29:04] company. Once you get a good grasp on [29:06] that then you just start fooling around [29:09] right because there you can just find [29:11] new ways for things to happen that [29:13] benefit your customers or create new [29:15] opportunities. And that's the brilliance [29:17] of AI, right? AI is not smart. It's, you [29:21] know, it's book smart maybe, but it's [29:23] not street smart. It's not, you know, [29:25] entrepreneur smart. You've got to have [29:27] somebody there who guides it and helps [29:29] it. But until you have a seauite that [29:31] understands how it works, it's going to [29:34] be very difficult for that organization. [29:36] I mean, I literally sat with the head of [29:38] a a consumer food company and he was [29:41] talking to me about acquisitions and [29:43] this was months ago and he was like, [29:46] "Yeah, because of GLP1's yada yada [29:48] yada." And I'm like, "Okay, well, let's [29:50] do this. Let's take your number one [29:51] product, your cookie, right? And I'm [29:54] going to ask Chat GPT to create a [29:57] competitor that is more GLP-1 friendly [30:00] and will be priced lower. And I want a [30:02] full bill of materials. I want sources, [30:04] everything manufacturing. what I have to [30:06] do and in about 3 minutes we got back to [30:08] him and he was like oh [ __ ] he had no [30:11] idea [30:12] >> now if you have no idea that's a [30:14] question you can ask an LLM [30:16] you don't have no idea on how to enable [30:19] your company to use AI and that to me is [30:22] the greatest greater struggle for most [30:24] organizations now for entrepreneurs [30:26] asking that question and trying to [30:28] implement no matter what it is there's [30:31] no better time to be an entrepreneur [30:33] than right now you know There will be [30:35] the trillionaire in the basement. There [30:37] will be, you know, somebody who puts out [30:39] their own um agent swarm but does it on [30:42] a um entrepreneurial basis. You know, [30:46] now there's still challenges [30:47] particularly for agents. So agents don't [30:50] see social media posts. They can't [30:53] review them, right? And it's hard to get [30:55] transcripts for any material amount of [30:57] them. They can't, you know, watch ads or [31:00] see ads. And so if we're moving to an [31:03] agent-driven economy for individuals, [31:06] there's going to have to be a lot of [31:08] changes that occur in how we communicate [31:11] commerce to those agents. Like [31:12] literally, I was fooling around with one [31:14] of the guys in my company and we created [31:16] this thing and you can go check it out. [31:17] It's not truly active. It's called [31:19] agentfeeds.dev. [31:21] And the whole idea is you take the [31:22] transcript of your post and you just put [31:25] it into um agentfeeds.dev dev and then [31:27] you copy and paste it for anybody can [31:29] copy and paste, you know, anybody you [31:31] follow into their agents. Hey, follow [31:33] all the feeds for this and it takes all [31:35] the ads and gives you all the [31:36] information you need so your agent is [31:38] more up to date on those categories or [31:40] whatever. You're going to see, you know, [31:42] you're going to see an explosion of [31:44] those types of things, but we still have [31:46] to get through trust and you all the [31:48] things we all know about AI and the [31:49] issues we all know about AI. But in [31:51] terms of opportunities going back to [31:53] health care, the biggest challenge and [31:56] where AI I think is going to be have the [32:00] biggest impact other than clinical is by [32:04] patients by consumers, right? And being [32:07] able to look at the things that you are [32:09] given on the economic side that you know [32:12] uh the benefits bill, right? The EOB, [32:14] right? The explanation of benefits, [32:16] right? And here's where I think um [32:18] consumers will get the greatest benefit. [32:21] So right now there's terror in I don't [32:25] know half the country, right? 40% of [32:27] people in the country can't afford a [32:29] $400 emergency bill. And so what I [32:32] always tell people is before anything [32:34] happens, go into your favorite AI model [32:37] and say get me a list of all the [32:39] nonprofit hospitals. go to go to them [32:42] and ask them what their financial [32:44] support services are because all um all [32:48] nonprofit hospitals have to have [32:50] financial assistance programs and some [32:52] of them are really good and for some [32:54] people you're better off and I don't [32:56] want to make the decisions for people [32:58] but you can ask the questions of the AI [33:00] to say whatever my um insurance plan [33:03] premium was going to be I'm going to put [33:05] it in a money market fund and let it [33:07] collect interest because I've already [33:09] discussed my situ situation with the [33:11] local nonprofit hospital and I know [33:13] everything there is to know about their [33:15] financial assistance plan. Now those [33:17] financial assistance plans are created [33:20] and the pricing is a reference price to [33:22] the federal pover poverty levels in most [33:24] cases but it can go up to 600% of [33:27] federal pro poverty level which can be [33:30] over $100,000 for some families in some [33:32] states. So patients slashconsumers [33:36] slashfamilies [33:37] understanding what their options are and [33:40] how to procure those options from [33:42] particularly nonprofit hospitals is [33:44] going to be enormous. If I was going to [33:46] start a company um in this space, I [33:50] would go to every nonprofit hospital and [33:53] set up a plan that post agents that I [33:57] enable people to use. Hey, you know, if [33:59] you're concerned about how you're going [34:00] to be able to pay for your bills or your [34:01] family bills and you, you know, you [34:03] don't have much money in the bank, [34:04] whatever you're making under X number of [34:06] dollars, copy and paste this into your [34:09] Muse or into your DOT or into, you know, [34:12] your um Claude Co-work, whatever it is, [34:15] and it'll know to come here to us and [34:18] ask questions. And so when I taught the [34:20] heads of hospitals, I'm like, you don't [34:22] understand. You guys suck at marketing. [34:25] You are dependent on the buas and their [34:28] plans and being part of their network to [34:30] feed you patients. That's ridiculous, [34:33] right? You if you make it easy for [34:36] people to use your financial assistance [34:38] programs, maybe go to a local bank, [34:41] maybe show people how to learn use um [34:43] stop-loss for for smaller medium-sized [34:45] companies. So many options for them to [34:48] use it to make things better for [34:50] patients because that's really where the [34:52] big disconnect is. You can offer better [34:54] plans. You can use technology to reduce [34:57] the price and become more efficient in [34:59] how you create a network or negotiating [35:01] direct contracts. But until the end user [35:04] truly [35:06] embraces it and knows how to use it, [35:08] there's going to be challenges. But all [35:10] of us at some level, just like we [35:12] learned to use spreadsheets back in the [35:14] day when we thought it was too [35:15] complicated. I'm old enough to remember [35:16] when people thought spreadsheets were [35:18] hard, you know, and you had to explain [35:20] to them and they had to pay $500 for [35:22] Lotus 123. But the same thing is [35:25] happening now as we go through this [35:27] transition and people, yeah, there's a [35:29] lot of people who are anti-AII, but [35:31] there are a lot of people who are [35:32] anti-cal, anti- everything. That's just [35:35] a matter of time. Um, but once you get [35:37] the way you get them to overcome AI is [35:41] their fear of AI is to show them how [35:43] these are the things that can really [35:45] benefit you and protect you and reduce [35:48] the inherent fear that you have in the [35:50] event that something goes really really [35:53] wrong. [35:54] >> Yeah. There's this um famous Aaron [35:56] Schwarz quote from many years ago. You [35:58] know, information wants to be free. Um [36:00] Yeah. And uh and I know in healthcare in [36:03] a previous conversation you've been a [36:04] bit skeptical that that will happen [36:06] because as you mentioned there's a lot [36:07] of siloed data and there's a lot of you [36:08] know strategic reasons why why that data [36:10] is is is you know that that is their [36:12] their advantage to some degree and and [36:13] so I say that to ask you what do you [36:15] think the ultimate impact of the [36:17] frontier labs you know open AI and [36:18] thropic have have very big ambitions in [36:20] the space either them or others will be [36:22] in in re reshaping uh healthcare or sort [36:25] of you know [36:25] >> I'll tell you exactly I'll tell you [36:27] exactly um and I'm selling my own book [36:29] here a little [36:31] The cost of designing a drug [36:33] personalized to you after reviewing your [36:36] DNA and knowing everything that it knows [36:38] will start approaching zero as the [36:41] capabilities of models go up. Right? We [36:44] talk about GPUs and how they'll get [36:46] faster, the networks behind them, the [36:48] power required, but it's the algorithms [36:50] that are going to change everything and [36:51] make them more efficient. Right? And we [36:53] don't even know what the speed of [36:54] improvement are going to be on [36:55] algorithms. at some point in time, [36:57] whether it's 5 years, 10 years, 20 [36:59] years, they're going to take something [37:01] from Eric, Julie, and Mark, and they're [37:03] going to say, starting with over the [37:04] counter, because if you think about it, [37:06] right, you walk into a drugstore, you [37:08] get this, you know, um, excuse me, [37:12] whatever, Advil, Tylenol, right, [37:14] ibuprofen, and we all think it's going [37:16] to impact us the exact same way. And we [37:20] have to experiment to see how it impacts [37:22] our body. the body makes no sense [37:24] whatsoever. [37:26] And so as the processing power and the [37:28] analytics power of these models from the [37:30] frontier models gets better, they will [37:33] be able to really truly personalize over [37:36] the pro over-the-c counter drugs without [37:38] a lot of the mishagos you have to go [37:39] through to try to figure these things [37:41] out, right? And now all of a sudden if [37:43] here's my personal um ibuprofen, here's [37:46] my personal dose or mixture of whatever [37:48] these over-the-c counter drugs, bam, you [37:50] start to change it. Then you get into, [37:53] you know, making other drugs that are [37:55] personalized for you because again, the [37:57] fact that we all take Eloquis and decide [37:59] between Eloquis or Zerelto or Warfare [38:02] makes no sense whatsoever in the big [38:03] scheme of things. And so being able to [38:06] take those things and personalize that [38:08] medicine. And what I have told two of [38:10] the Frontier monks, I said, "If you [38:12] really want to be smart, you take your [38:15] $20 or your $200 um subscription and you [38:19] include that service once it's available [38:23] because your marginal cost for doing [38:25] this at that point in time, look, the [38:28] inference and everything that has to [38:29] happen just to respond to a request [38:31] today expensive like this, right? Coming [38:34] down very quickly. But the same thing is [38:36] going to happen for this type of [38:38] personalized medicine. Initially it's [38:40] going to be enormous. But as we [38:42] understand the human body more and [38:44] understand all the variables in our body [38:46] more and our brains more etc and [38:48] understand the the medications and [38:50] figure out how to do the end of one for [38:52] everybody. It will be part of a normal [38:56] subscription because there's no reason [38:57] it should be. How expensive is 23 and [38:59] me? You pay $99 or less now to get your [39:02] DNA looked at. And so maybe I pay $99 [39:06] upfront. I give them my DNA if I'm [39:08] willing to do that. You know, obviously [39:10] for privy privacy concerns, they store [39:12] it. They continue to bam bam bam bam bam [39:14] bam. You know, maybe you want to know [39:16] what could be wrong. Maybe you don't [39:17] want to know what could be wrong based [39:19] off of your DNA. But if something does [39:21] go wrong, [39:23] >> they have access to all these drugs, all [39:26] these opportunities, and the ability to [39:28] create them in real time. and selling my [39:30] book. We want our pods to be right there [39:32] to be able to manufacture them because [39:34] we're the only ones capable of doing it. [39:36] And I don't see that changing for a long [39:37] time. [39:38] >> I think one of the things also, Mark, [39:39] that people um probably don't appreciate [39:41] as much as they should in that context [39:43] is that as that happens is what you just [39:46] described happens and as drugs become [39:47] just better products for like every [39:49] individual in the country or in the [39:50] world. Um that is actually one of the [39:52] most disruptive forces for care [39:54] delivery, right? like how much of [39:56] healthare is actually the job of the [39:58] doctor helping patients figure out why a [40:01] drug doesn't work for them and [40:02] calibrating and doing met titration and [40:04] changing behavior to make your your life [40:06] work for the drug as opposed to the [40:08] other way around. And so um that's [40:10] something that I think you know [40:11] >> but remember because of that latency I [40:12] mentioned earlier you're still going to [40:13] need doctors if Mark walks into the [40:16] hospital and I just tried this new [40:18] personalized um medicine and I just [40:20] start puking my guts out. [40:21] >> Yeah, you still need tele. [40:23] >> You can have it on video, right? Then [40:24] you can have a robot there say, "How do [40:26] you feel, Mark?" Right? And the [40:27] Terminator might might walk in and say, [40:29] "Your time is up." I don't know. But but [40:32] I'd rather have a human there with all [40:34] five senses being able to take a look [40:36] and ask questions and see the crying mom [40:39] or the crying son or child or whatever [40:41] and be able to include that in the [40:43] context. And so I don't think ever that [40:46] will replace doctors and we shouldn't [40:47] even try because and and you know, you [40:50] guys know how adoption of technology is [40:52] particularly for this. You still have to [40:54] know the questions to ask. [40:57] >> You still have to know what the [40:58] variables are that matter versus the [41:00] ones that don't. You still have to [41:02] realize that even as processing costs [41:05] drop towards zero hopefully at some [41:06] point in time that you know there's [41:09] still a cost associated with it even if [41:11] that cost is only time. And so you know [41:14] you need somebody there who's been [41:16] educated in all those pieces. I think to [41:18] your point, Julie, where things might [41:20] change dramatically when it comes to the [41:22] the role of the doctor is how they'll be [41:24] trained in medical school. They won't be [41:27] taught the exact same things. They'll [41:29] have to learn how to use open evidence [41:30] or whatever else is available out there [41:32] to and how to extract information even [41:36] if it's just that DNA information and [41:38] understanding what's in there and what [41:39] the model thinks about it and being able [41:41] to translate that to the person because [41:44] you know [41:46] effectively in order for this to work [41:48] perfectly everybody has to have their [41:50] own model and that's going to be [41:53] difficult for everybody even though [41:54] there's going to be millions or not if [41:56] not hundreds of millions or billions of [41:58] models [41:59] created and supported over the next [42:00] years. And plus on top of that, IP [42:03] becomes a totally different problem that [42:07] gets introduced into this equation and [42:09] process because you know up until [42:12] recently it's been publish or perish. [42:14] And if you're a doctor and you create [42:15] something, you want everybody to happen, [42:17] maybe you can even license it and make [42:18] some money off of it. But now, you know, [42:20] if you try to patent something, every [42:22] 12-year-old is saying, "Hey, look at [42:24] this patent, change it just a little bit [42:25] and make my own patent." Right? or if [42:28] it's, you know, a new procedure in [42:30] healthcare, you know, you might say, [42:31] "No, you have to come to my model and [42:33] you have to pay me $9,999 [42:36] every access, right? Or to use [42:38] inference, you know, you're going to use [42:40] this software that I require because [42:43] nobody's going to give away that IP for [42:45] free." And that creates a lot more [42:47] problems. I think part of the [42:49] underpinning that a lot of AI [42:50] entrepreneurs have is that going back to [42:52] Erica, information wants to be free. the [42:55] information wh may want to be free but [42:57] the person who owns the IP feels [42:59] differently and so that's going to [43:01] change how we interact with models and [43:04] you know we can argue about you know [43:07] frontends that choose which model is [43:09] least expensive to answer the question [43:12] but we haven't had the discussion on [43:14] where we find the IP that's needed to [43:17] either train that model post- trainin [43:18] that model you know rag that model [43:21] whatever it may be if that person isn't [43:23] making it available but It's absolutely [43:25] required. Does that make sense to you [43:27] guys or do you guys think I'm an idiot? [43:28] >> You know, I think it's really [43:29] interesting because it also brings up [43:30] the point of like what is the role of [43:31] the doctor in the future? It so number [43:33] one, I agree that actually I think we're [43:34] going to need more doctors in the future [43:36] because as care uh advice becomes more [43:38] abundant, more people are going to [43:40] demand healthcare, actual like real life [43:42] healthcare services. And so we're going [43:43] to find we actually need more doctors. [43:45] And um there's something to be said [43:46] about what you what you're describing as [43:48] like the role of the doctor today is [43:50] very rote, right? It's kind of like the [43:52] these are the tasks you got to do these [43:53] quality measures. It's like you you like [43:55] barely need to use your brain honestly [43:57] for a lot of the things that doctors are [43:58] asked to do in the traditional [43:59] healthcare setting. And what you're [44:01] describing is like what if like the [44:02] paradigm moves towards physicians are [44:04] actually like more physician scientists, [44:06] right? Like it's actually their job is [44:07] to take like the bleeding edge of [44:09] information that we may not know at [44:11] population scale yet, but on an [44:13] individual basis they're at the tip of [44:14] the spear of collecting novel data, [44:16] generating novel insights about how [44:17] people are reacting. [44:18] >> Novel data by definition stimulating job [44:21] description to me. [44:22] >> Yes. [44:23] >> Yes. Because by definition, you're [44:25] exactly right. Right. Novel data equals [44:28] person. [44:29] >> Mhm. [44:30] >> Exactly. And with like data, [44:33] >> we're going to have longitudinal [44:34] monitoring. You know, like the blood [44:36] pressure is the one that like we always [44:37] talk about is where, you know, it's kind [44:39] of the same principle as what you're [44:40] saying. The fact that we take our blood [44:42] pressure like once a year is kind of [44:43] ridiculous because it changes. [44:45] >> Not me. [44:45] >> I got this [ __ ] right here. [44:47] >> You're Yeah, you're cutting edge. And [44:48] you know, but soon we're going to have [44:49] wearables that are just measuring it in [44:51] real time like every single day. And [44:52] like you'll have a much more precise [44:53] understanding of how you're responding [44:55] to different therapeutic interventions [44:56] and even like diet and exercise and all [44:58] that kind of stuff. And you know that's [45:00] going to you bring up a good point Julie [45:02] in terms of novel um information and [45:06] that's everybody in terms of finding [45:09] jobs, right? You're going to need AI [45:12] translators for people who may not keep [45:14] up with these things. you know, regular [45:16] people that are in wherever in this [45:18] country or in the world who just, you [45:21] know, want to live their abundance life, [45:23] whatever that may be. And you're going [45:25] to need people who are going to be the [45:28] translators for what's novel about this [45:30] circumstance or this individual and how [45:32] do you, you know, make it valid to AI [45:35] and the output of the AI valid to the [45:37] novel to the individual. That's going to [45:39] be a job and it's going to be very [45:42] difficult to extract everything um from [45:45] an individual that the AI is going to [45:47] need and you're gonna have need to have [45:48] a person I think there to do it. Maybe [45:51] somebody envisions a humanoid robot that [45:54] is going to ask you those questions and [45:56] somebody's going to be comfortable. I [45:58] don't I don't think I don't think that's [45:59] going to happen. [46:00] >> Yeah. [46:01] >> By the way, Mark, I don't think I've [46:02] ever heard you talk about another set of [46:04] entrenched incumbents, which is the EHR [46:06] companies. [46:07] >> Uhhuh. What what's your what's your [46:08] theory of the case there on how that [46:11] that market changes or evolves or [46:13] doesn't um in the age of AI and what [46:15] that looks like in the next few years? [46:17] >> Honestly, I don't know. You know, the [46:19] EHR is dominated by Epic and it's their [46:22] world, you know, and so I've just kind [46:24] of deferred to them and tried to stick [46:27] where I can have an impact because, you [46:28] know, we partner with them. We think [46:30] offering um pricing particularly [46:33] pharmaceutical pricing at the the point [46:36] of um script where the doctor is there [46:38] offering them different options is a [46:41] >> part of that new announcement that they [46:42] just made about the [46:43] >> Yeah, exactly. Exactly. with Epic and [46:45] Amazon etc. Um so I think that's a big [46:48] plus and I think that's needed but in [46:50] terms of their actual business and where [46:51] it's disruptible I'm not really the one [46:53] qualified for that. [46:54] >> Okay. My problem with, by the way, with [46:56] that announcement was that they I love [46:57] that they announced it and then they [46:59] said it's not going to be available till [47:00] May of next year and I was like, why [47:02] take so long? [47:02] >> I had nothing to do with that. [47:04] >> Okay, [47:05] >> that's typical in this industry, right? [47:07] >> Yeah. Do do you guys think that in 10 [47:09] years uh you know healthcare is still [47:12] going to be a fifth or a sixth of [47:14] whatever it is now of GDP and that [47:15] there's kind of this just sort of [47:17] terminal as it sort of terminal state [47:19] where there's just you know way more [47:20] demand than um than sort of you know we [47:23] can supply and just as it gets easier as [47:25] it gets more efficient we're still and [47:26] as GDP grows you know even 5% a year [47:28] hopefully it's at some point our demand [47:30] is still going to just cap at you know [47:32] 1/5if of the economy. [47:33] >> I do. [47:34] >> Yeah. [47:36] But the value that we get out of that [47:38] spend should be [47:39] >> well the value you get out of the people [47:40] will increase. [47:42] >> Yeah. [47:42] >> Because they'll be healthier. Yeah. [47:43] >> So there's a difference when it's health [47:45] when it's sick care, right, as a lot of [47:48] people refer to um versus when it's [47:50] keeping people healthy and they're more [47:52] productive and there's less downtime and [47:54] you know they're they're smarter because [47:56] it's easier to learn etc. Um so I think [47:59] we'll get greater productivity that'll [48:00] more than account for it which we don't [48:02] get now. Z zooming out a bit, you know, [48:04] Mark, we both we have a mutual friend [48:06] who's a very prominent pollster. I won't [48:08] out him here, but he um he he he he [48:11] believes that or he's done some work to [48:12] indicate that um if you ever ran for [48:15] office, he thinks you could win. Now, of [48:17] course, you you you've said you never [48:18] you you'll never run. Um, so but so [48:20] we're just speaking hypothetically now, [48:21] but I if if you were president or if you [48:23] were advising the the the next [48:25] president, I'm I'm I'm curious how how [48:27] you would uh mo, you know, think what is [48:29] the leverage to most address sort of our [48:31] our healthcare challenges and then I [48:32] want to hear your your broader uh sort [48:34] of, you know, policy positions you'd be [48:35] most. [48:36] >> It's really easy. It's the same thing I [48:37] tell states, you know, that I've [48:39] testified for. One, make all contracts [48:42] with anybody who takes taxpayer money [48:44] public. No redactions. because the [48:47] minute that happens, you start to have [48:49] an efficient market and the costs go [48:51] down. Two, make it so that anybody who [48:54] can find a better price for less than [48:56] their current out- of- pocket with their [48:58] plan, make it apply to their deductible. [49:00] Allow it to apply to their deductible. [49:02] Eight states do that at some level [49:04] already. Um, three, for nonprofit [49:07] hospitals, require them to publish their [49:09] entire general ledger down to each [49:11] detailed entry and all their procurement [49:14] um, receipts and and requirements, [49:18] right? So that everybody gets to see it. [49:20] It's our money. We're the taxpayers, [49:22] right? Four, instead of um [49:27] current insurance plans the way we have [49:29] them, 72% of those big carriers um [49:32] revenue comes from taxpayers. They don't [49:35] take risk anymore. They off it. [49:37] Everything's an arbitrage for them. So, [49:39] knowing that, we also have to consider [49:41] that the one debt we never pay off till [49:44] the day we die is our insurance [49:47] premiums. [49:48] Think about that. whether it's Medicare, [49:51] unless you're on Medicaid, right? You [49:53] are paying till the day you expire and [49:57] when you need it, you have to fight for [49:59] it in the current system and probably [50:01] foreseeable systems. to me if we were [50:04] able to create a program where you just [50:06] deposited what would be let's just say [50:09] how much you'd pay for a premium under [50:11] the an ACA silver plan in your state and [50:14] we just went and did a deal with the [50:15] bank and we said okay in Texas for a [50:17] family of five it's $2,100 at your [50:20] income right so you just keep on [50:22] depositing $2,100 and it cruise and you [50:24] own it but it has to be deposited if you [50:27] want to participate in this program and [50:29] then if you have a um medical incident [50:33] or pharmaceutical incident, right? You [50:35] can take that money. If it's not enough, [50:37] we've worked out a deal with the bank [50:40] where two things happen. One, the bank [50:42] will loan you money up until a a point [50:46] where stop-loss kicks in, which means [50:48] we're going to take part of that money [50:50] you deposit and use it for stop-loss [50:52] coverage. and two, the federal [50:54] government or the state is going to [50:56] guarantee that loan to you so that the [50:58] provider is not out and we're still [51:01] going to, you know, deduct it from your [51:02] payroll so that you pay it back. And if [51:05] you know, you're lucky and you never [51:06] have an incident and you get to save all [51:08] that money when you turn 65 and go on [51:10] Medicare, you just get all that money [51:12] and all the acred interest. Because if [51:14] you think about it, [51:16] the federal government will, you know, [51:19] >> like our internet [51:20] >> cover or um guarantee your student [51:24] loans. They'll guarantee SBA loans. [51:28] They'll guarantee home loans or give you [51:30] a down payment, right? [51:32] >> Third world country. [51:33] >> We'll guarantee all these things, even [51:35] agricultural things. But the most [51:37] important thing, you know, covering our [51:39] health care, good luck. you know, you're [51:41] in a bad accident, good luck to you, and [51:43] we'll maybe push it off to the [51:45] hospitals. They have to take you in. So, [51:47] I would create a plan that says you have [51:50] to, you know, you have to um deposit [51:53] this money. The bank will have a [51:55] guarantee just like a mortgage, [51:57] whatever. We'll loan you this money and [51:58] then we'll have federal stop-loss [52:00] programs above some amount, 40,000, [52:04] whatever it may be. Now, all of a [52:06] sudden, bye-bye insurance companies. Now [52:09] all of a sudden you're not fighting back [52:10] because it's your money to spend as you [52:12] choose. Now we'll have to set thresholds [52:14] on where and how you could spend it. So [52:16] you don't just go give it to your cousin [52:18] Billy who said he's going to fix your [52:20] fix your broken toe, right? But within [52:22] those constraints, I think now all of a [52:24] sudden we have a better system. So [52:27] that's what I would do if I was advising [52:29] um in terms of healthcare. [52:30] >> What what about u you know one of your [52:32] gifts is is storytelling and and [52:34] marketing more generally. What about the [52:36] AI industry in terms of you obviously AI [52:38] is you know uniquely unpopular in in in [52:41] in the US if you were advising you know [52:43] open AI if you're advising anthropic on [52:44] how to sort of ch change those numbers [52:47] and then there's the whole sort of data [52:48] center uh sort of saga I'm curious what [52:51] your advice would be to the broader AI [52:52] industry. I've had these conversations [52:54] right with them and I told them they're [52:56] idiots, you know, because what controls [52:59] how every pretty much everybody in this [53:01] country thinks right now? Social media [53:03] algorithms. [53:07] Literally, I was having a conversation [53:08] with a 20 23-year-old friend that I work [53:12] with and we're talking politics. We're [53:13] discussing who we voted for yesterday [53:15] and how and why. And I said, "What about [53:17] your friends, the other 23 24 year [53:19] olds?" and they said that their friends [53:23] didn't even know living in Texas didn't [53:25] even know who Ken Paxton or James Terico [53:27] were [53:29] >> or are right which is insane in my mind [53:32] right insane in this person's mind but [53:34] it reinforces the fact that you get more [53:37] of what you seek via algorithms and if [53:41] you really have the best AI you should [53:44] be able to not only reverse engineer [53:46] those algorithms but put together a [53:48] marketing marketing program because you [53:50] sure tell everybody you can do marketing [53:51] programs through you know your your bots [53:54] your bot or dot or whatever and really [53:57] start marketing there because this [53:59] applies to politics it applies to AI it [54:02] applies to everything in this country [54:05] the divisiveness we all have our unique [54:08] AI feed in the social media platforms we [54:11] use and those platforms don't give a [54:14] [ __ ] what it feeds you within some [54:16] minimal constraints and So everybody [54:19] looks at the world differently. The days [54:22] particularly for younger people of [54:24] thinking, you know, just buy more ads [54:27] and ruin our football games and our [54:29] basketball games and everything's fine. [54:31] You know, maybe older people vote more [54:33] and that's maybe why, but it's useless [54:35] when you're trying to change hearts and [54:37] minds about AI specifically. Even though [54:40] the irony of it all is that the it's the [54:42] AI behind the the algorithms that's [54:45] ruining everything. But as long as [54:47] section 230 is there, we are where we [54:50] are at. And as long as you know, unless [54:52] we take a Australia type approach or [54:54] some states type approach of 16 and [54:56] under, then my what I told them [54:58] specifically, you need to use your AI to [55:03] segment everything and figure out the [55:05] best way to put together marketing, [55:07] promotion, and however else you want to [55:10] do it. Do it like the Russians do it. It [55:12] doesn't matter, right? Because that's [55:14] what's at stake for you. But people, you [55:16] know, data center hate is just a proxy [55:19] for not being able to understand AI. [55:21] >> Yeah. [55:22] >> And not all know all the pieces there. [55:23] And I don't blame people at all. Right. [55:25] And just like employers have been really [55:27] dumb with their healthc care benefits, a [55:29] lot of communities have been really dumb [55:31] with the the deals they've negotiated [55:33] for data centers, you know, and they've [55:35] fallen for the contractual terrorism in [55:37] a lot of a lot of cases. But, you know, [55:40] to me, educating them about social media [55:45] and educa and educating our legislators [55:48] and whoever's president about social [55:50] media because I don't think they truly [55:51] understand the impact that we don't all [55:55] read the same newspaper, the same [55:56] magazines, look at the same websites, [55:58] watch the same news shows. We all have [56:01] our own unique TikTok feed. Your feed is [56:04] not like mine. Like the best way to find [56:07] out about your kids is to just look at [56:09] their social media feed. Like my [56:11] 17-year-old son, it's basketball, [56:13] basketball, basketball. Now I'm starting [56:15] to see a little bit of politics pop up, [56:17] but then hot girl, hot girl, hot girl, [56:18] basketball, basketball, car car. And I'm [56:21] like, okay, [56:22] >> typical 17-year-old guy, right? Um but [56:26] until the the big um frontier models [56:31] understand completely that they have to [56:34] figure out how to become part of [56:35] everybody's feed. [56:38] They're going to be putting out all [56:39] these position papers that are useless. [56:41] >> Yeah. No, I mean Mark, we agree with you [56:43] that what you said earlier about this is [56:44] like the best time to be alive and and [56:46] an entrepreneur. Um and you know, so [56:48] many things that again were intractable [56:50] uh historically are now all of a sudden [56:51] addressable. Is is there an area of the [56:53] market and you meet a lot of [56:54] entrepreneurs and see you know sort of [56:55] people building in all sorts of areas of [56:56] the world. Um are is there like some [56:59] area where you're like why is no one [57:01] building here like that you think is [57:02] still a whites space opportunity for [57:04] entrepreneurs? [57:05] >> Um all of them you know seriously you [57:10] know when I go talk to kids um and I [57:14] always tell them there's going to be two [57:15] types of companies. Those who are great [57:17] at AI and those who have gone out of [57:19] business. And if you take the time to [57:21] learn and then there's two types of [57:23] people and how they use AI. Those who [57:25] use AI to learn anything and those who [57:28] use AI so they don't have to learn [57:30] anything. And if you're one of those [57:32] people who uses AI so that you can learn [57:34] anything and you realize what type of [57:37] companies and problems aren't being [57:38] solved by AI, don't be shy to just talk [57:42] to your AI, you know, and I say this not [57:44] just to kids to 50 year old, 60, 70 year [57:46] old entrepreneurs. The biggest challenge [57:49] right now with people, entrepreneurs [57:52] using AI is the comfort level of talking [57:55] to your AI, whether it's by voice or [57:58] typing, whatever it is, because it's [58:00] there's still a lot of hesitancy. You [58:03] know, just like back in the day, those [58:04] first spreadsheets, people still had [58:05] their 10 key adding machine and they [58:07] would check it to make sure the [58:08] spreadsheets were right. You still you [58:10] do have to check the output but you have [58:12] the opportunity to take the output of [58:14] gro and put it into chat GPT and the [58:17] output of like when I go through all [58:18] these contracts I was telling you about [58:20] I start with one and said hey one of [58:22] your peers came out and said this about [58:24] this contract what do you think and [58:25] spend a couple hours that's all young [58:28] entrepreneurs so when you ask me is [58:30] there one thing I truly believe it's [58:33] everything everything will change this [58:35] is the greatest transitional technology [58:38] we have ever seen and I'm on I've been [58:40] around for all of them, right? And this [58:42] blows them all away. The hardest part is [58:47] just going for it. And that's where [58:48] Silicon Valley and, you know, kids from [58:51] the the Bay Area, I think, have a little [58:53] bit of an advantage because they see [58:54] their parents and friends and the [58:55] culture there as little go. [58:58] But I think the rest of the country and [59:01] the rest of the world once they get that [59:03] confidence level, you're going to start [59:05] to see businesses we never imagined pop [59:07] up because we're not seeing that yet. [59:09] You know, we're not seeing companies [59:11] where it's like, oh, what is that? You [59:13] know, why are they doing that? You know, [59:15] what is the opportunity there? And then [59:17] they realized it before we did, right? [59:20] It's kind of like Fster, you know, first [59:22] like, whoa, what was that? And so I [59:25] think the biggest [59:28] thing to focus on if you're, you know, [59:31] looking for something is ask anything. [59:34] You I mean, I do it all the time. It's [59:37] just like, "What do you think about [59:37] this? What do you think about this? What [59:38] do you think about this?" You know, I've [59:40] held phones up next to each other and [59:41] take the output and had them have a [59:43] conversation with each other so I could [59:45] listen in. Don't be shy about using AI [59:48] in things that feel really uncomfortable [59:50] and weird because that uncomfortableness [59:53] is probably the path to something that [59:55] is groundbreaking and gamechanging. [59:57] >> That's a great note to to wrap on. Mark, [59:59] thank you so much for coming on the [60:00] podcast. [60:00] >> It was fun. Thanks, guys. Thanks, Julie. [60:02] Thanks, Eric.